Results 151 to 160 of about 1,999 (189)
Effect of Different High-Temperature Heating Methods on the Glycation Reaction and Advanced Glycation Reaction Products of <i>β</i>-Lactoglobulin. [PDF]
Zhang X +8 more
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Renal N ε-Carboxymethyllysine Deposition After Kidney Transplantation
Accumulation of advanced glycation end products, that is, N(epsilon)-carboxymethyllysine (CML), induces oxidative stress and inflammation, and is present in chronic renal failure. Proximal tubular cells (PTCs) take up advanced glycation end products-bound proteins by apical megalin-receptors and degrade them.
Marcus, Baumann +7 more
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Modification of collagen in vitro with respect to formation of Nɛ-carboxymethyllysine
International Journal of Biological Macromolecules, 2009Developing new biopolymer-based materials with bio-identical properties is a significant challenge in modern science. One interesting route to this goal involves the biomineralization of collagen, a pre-structured and widely available protein, into a material with interesting properties. A prerequisite for biomineralization is the ability of cations (e.
Hermann Ehrlich +2 more
exaly +3 more sources
Effect of Diabetes and Aging on Carboxymethyllysine Levels in Human Urine
Carboxymethyllysine (CML) has been identified as a modified amino acid that accumulates with age in human lens proteins and collagen. CML may be formed by oxidation of fructoselysine (FL), the Amadori adduct formed on nonenzymatic glycosylation of lysine residues in protein, or by reaction of ascorbate with protein under autoxidizing conditions.
Knecht, K J +6 more
openaire +3 more sources
Temporal Increases in Urinary Carboxymethyllysine Correlate with Albuminuria Development in Diabetes
<i>Background/Aims:</i> Advanced glycation end products (AGEs) mediate progressive tissue damage in diabetic nephropathy; however, their utility as a noninvasive reliable biomarker of progressive diabetic nephropathy remains to be determined.
Coughlan, Melinda T. +1 more
openaire +6 more sources
Hydrocolloid effects on Nε-carboxymethyllysine and acrylamide of deep-fried fish nuggets
Food Bioscience, 2021Abstract The safety of breaded and deep-fried foods has received more attention recently. The purpose of this study was to investigate the effects of hydrocolloids on the contents of Ne-carboxymethyllysine (CML) and acrylamide (AA) in breaded fish nuggets, and the relationship between the AA, CML and physicochemical properties.
Caihua Jia, Jianhua Rong, Ru Liu
exaly +2 more sources
Journal of Chromatography A, 2007
An accurate method for the quantification of carboxymethyllysine (CML) in food samples is evaluated. CML, a stable advanced Maillard compound, is considered as an useful marker of protein damage in severely heated foods. The proposed GC-MS method stipulates double derivatisation of amino acids and quantification by selected ion monitoring.
Amélie, Charissou +2 more
exaly +3 more sources
An accurate method for the quantification of carboxymethyllysine (CML) in food samples is evaluated. CML, a stable advanced Maillard compound, is considered as an useful marker of protein damage in severely heated foods. The proposed GC-MS method stipulates double derivatisation of amino acids and quantification by selected ion monitoring.
Amélie, Charissou +2 more
exaly +3 more sources
Serum Carboxymethyllysine Predicts Mortality in Hemodialysis Patients
American Journal of Kidney Diseases, 2006Hemodialysis patients show markedly elevated serum levels of advanced glycation end products (AGEs). AGEs have been implicated in the pathogenesis of vascular damage and are regarded as a class of uremic toxins. However, to date, serum AGE level could not be identified as an independent predictor of mortality.
Zoltán, Wagner +9 more
openaire +2 more sources
N ε-Carboxymethyllysine in diabetic and non-diabetic polyneuropathies
Acta Neuropathologica, 2002Increased oxidative stress and advanced glycosylation are important factors in the development of diabetic neuropathy. In non-diabetic neuropathies their influence has not been investigated in detail so far. We studied the localisation of N(epsilon)-carboxymethyllysine (CML) - a biomarker for oxidative stress - by immunohistochemistry in sural nerve ...
K M, Haslbeck +5 more
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