Results 71 to 80 of about 6,236 (183)

A European consensus recommendation on the management of delayed methotrexate elimination: supportive measures, leucovorin rescue and glucarpidase treatment

Journal of Cancer Research and Clinical Oncology
High-dose methotrexate (HDMTX) is used in the treatment of a range of adult and childhood cancers. Although HDMTX can provide effective anti-tumor activity with an acceptable safety profile for most patients, delayed methotrexate elimination (DME ...
Stefan S. Bielack, Carole Soussain, Christopher P. Fox, Caroline Houillier, Thais Murciano, Wendy Osborne, Pier Luigi Zinzani, Carmelo Rizzari, Stefan Schwartz   +8 more
doaj   +1 more source

Role of carboxypeptidases to the free amino acid composition, methylpyrazine formation and sensory characteristic of under- fermented cocoa beans [PDF]

, 2010
The role of carboxypeptidases B (from porcine) and Y (from baker's yeast), applied to under-fermented cocoa beans, on the formation of cocoa-specific aroma precursors, the aroma and sensory quality after roasting was investigated.
Lioe, Hanifah Nuryani, Selamat, Jinap, Yusep, I., Bakar, Jamilah, Saari, Nazamid   +4 more
core   +2 more sources

A Preliminary Study of the Activation of Endogenous Pancreatic Exocrine Enzymes during Automated Porcine Islet Isolation

Cell Transplantation, 1999
The activation of endogenous pancreatic enzymes during automated pancreas digestion may be detrimental to islet isolation. In this report we assessed the activation of trypsin, chymotrypsin, elastase, carboxypeptidases A and B, phospholipase A 2 , and ...
S. A. White MD, FRCS, H. Djaballah, D. P. Hughes, D. L. Roberts, H. H. Contractor, S. Pathak, N. J. M. London   +6 more
doaj   +1 more source

Tissue carboxypeptidases activity of the women w ith womb body oncopathology

, 2004
Досліджена активність карбоксипептидаз А і В доброякісних та злоякісних новоутворень тіла матки. Встановлено, що у доброякісних новоутвореннях активність карбоксипептидаз змінюється в залежності від проліферуючого потенціалу пухлинних клітин міометрія та
Блохін, Ю. В., Вовчук, Iрина Леонiдiвна, Раздражнюк, Г. С., Чернадчук, Снежана Сергеевна, Vovchuk, Iryna L., Блохин, Ю. В., Razdrazhnuk, G. S., Чернадчук, Сніжана Сергіївна, Вовчук, Ирина Леонидовна, Chernadchuk, Snizhana S., Blohin, U. V.   +10 more
core   +1 more source

Immunohistochemical Localization of Carboxypeptidases D, E, and Z in Pituitary Adenomas and Normal Human Pituitary

, 2002
Carboxypeptidases may play important role(s) in prohormone processing in normal and neoplastic adenohypophyseal cells of the pituitary. We have recently demonstrated carboxypeptidase E (CPE) and carboxypeptidase Z (CPZ) in the majority of ...
Lewis S. Blevins, George S. Allen, Xuemo Fan, Sandy J. Olson, Mahlon D. Johnson   +4 more
core   +1 more source

Angiotensin processing is partially carried out by carboxypeptidases in the rat mesenteric arterial bed perfusate

, 2008
Here we investigated the possible association between the carboxypeptidase A (CPA)-like activity of the rat mesenteric arterial bed (MAB) perfusate and the ability of this fluid of forming angiotensin (Ang) 1-9 and Ang 1-7 upon incubation with Ang I and ...
OLIVEIRA, Eduardo B., PEREIRA, Hugo J. V., SALGADO, Maria Cristina O., SOUZA, Laura L.   +3 more
core   +1 more source

Discovery and characterizatopn of small molecular weight metallocarboxypeptidase inhibitors [PDF]

, 2010
Descripció del recurs: el 02 de novembre de 2010Las hidrolasas son enzimas que catalizan la ruptura del enlace amida o peptódico, y por lo tanto son denominadas también proteasas o peptidasas. Las proteasas constituyen cerca del 2 % del genoma humano, lo
Fernández Fleischhauer, Daniel, Avilés, Francesc Xavier, Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular   +2 more
core   +1 more source

Zebrafish Cytosolic Carboxypeptidases 1 and 5 Are Essential for Embryonic Development [PDF]

, 2013
The cytosolic carboxypeptidases (CCPs) are a subfamily of metalloenzymes within the larger M14 family of carboxypeptidases that have been implicated in the post-translational modification of tubulin.
Fricker, Lloyd D., Sapio, Matthew R., Lyons, Peter J.   +2 more
core  

Phylogenetic analysis of carboxypeptidases from C. sordidus and other insect species (accession numbers are given).

, 2016
Phylogenetic analysis was conducted in MEGA6.0 using the Neighbor-joining method. Positions containing alignment gaps and missing data were eliminated only with pairwise deletion.
Seong-il Eyun (549328), Manuel Aristizabal (3181638), Alberto Soto (3181644), Haichuan Wang (362568), Arnubio Valencia (3181635), Blair Siegfried (652110), Jorge W. Arboleda (3181641), Daniel D. Noriega (3181647)   +7 more
core   +1 more source

THE SPECIFICITY OF CARBOXYPEPTIDASE

Journal of Biological Chemistry, 1946
M A, STAHMANN, J S, FRUTON, M, BERGMANN
openaire   +2 more sources