Results 71 to 80 of about 5,868 (229)
Phytochelatins are synthesized by two vacuolar serine carboxypeptidases in Saccharomyces cerevisiae
Phytochelatins (PCs) are cysteine-rich peptides that chelate heavy metal ions, thereby mediating heavy metal tolerance in plants, fission yeast, and Caenorhabditis elegans.
Wünschmann, Jana +5 more
core +1 more source
Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen.
A novel basic carboxypeptidase clearly different from carboxypeptidase N has been isolated from human plasma. It circulates as an enzymatically inactive precursor enzyme bound to plasminogen. During fibrinolysis, it can be converted to its active form, carboxypeptidase U, through the action of plasmin. The active enzyme has an apparent molecular weight
Wang, W., Hendriks, D., Scharpe, S.
openaire +3 more sources
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki +10 more
wiley +1 more source
Hydrolyzed tannin 1,2,6-tri-O-galloyl-β-D-glucopyranose (1,2,6-TGGP) possesses significant medicinal properties. However, little is known about its underlying molecular mechanisms.
Yueqi Wang +7 more
doaj +1 more source
Garadacimab for the long‐term prophylaxis of hereditary angioedema
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün +5 more
wiley +1 more source
Genome-Wide Identification and Characterization of Carboxypeptidase Genes in Silkworm (Bombyx mori)
The silkworm (Bombyx mori) is an economically-important insect that can secrete silk. Carboxypeptidases have been found in various metazoan species and play important roles in physiological and biochemical reactions. Here, we analyzed the silkworm genome
Jifu Li +6 more
core +1 more source
IntroductionBotryosphaeria dothidea (B. dothidea) is a catastrophic fungal pathogen that threatens fruit production worldwide. Secreted peptidases like serine carboxypeptidases (SCPs) are well known to be involved in fungal virulence, but their role in B.
Muhammad Umer +7 more
doaj +1 more source
Dual IRE1 targets: Determinants of the cell fate?
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat +3 more
wiley +1 more source
Regulation of basic carboxypeptidases: Implications for extracellular hydrolysis of peptide ...
Gerd Birgitta. McGwire (7979264)
core
Phylogenetic analysis was conducted in MEGA6.0 using the Neighbor-joining method. Positions containing alignment gaps and missing data were eliminated only with pairwise deletion.
Seong-il Eyun (549328) +7 more
core +1 more source

