Results 81 to 90 of about 6,236 (183)

Methods and pharmaceutical compositions for treating tubulin carboxypeptidases associated diseases.

, 2019
Using chemical proteomics with a potent unique irreversible inhibitor, inventors found that major brain tubulin carboxypeptidase (TCP)is a complex of vasohibin-1 (VASH1) with the Small Vasohibin-Binding Protein (SVBP). VASH1 and its homologue vasohibin-2
Andrieux, Annie, Bosc, Christophe, Peris, Leticia, Delagrange, Philippe, Moutin, M.-J., Aillaud, Chrystelle   +5 more
core   +1 more source

Human glutamate carboxypeptidases II and III

, 2016
The herein presented Ph.D. dissertation describes kinetic and structural characterization of human glutamate carboxypeptidases II and III (GCPII and GCPIII) using a complete panel of their natural substrates.
Navrátil, Michal
core  

Chemical basis of fluorogenic substrate probe design: revisiting the past to discover the new in biochemistry. [PDF]

RSC Chem Biol
Komatsu T, Urano Y.
europepmc   +1 more source

Carboxypeptidase M deficiency aggravates complement-induced lung injury. [PDF]

iScience
Qadri F, Zhang C, Schütz A, Popova E, Czaplinska BA, Zemechmann K, Greckl R, Alenina N, Pesquero JB, Rodrigues AF, Bader M.   +10 more
europepmc   +1 more source

Detoxification of Ochratoxin a by <i>Weizmannia coagulans</i> CGMCC 9951: Characterization, Mechanism, and Application in <i>Cornus officinalis</i> Pulp. [PDF]

Toxins (Basel)
Shao C, Li Y, Wu Y, Zhao L, Tian P, Gu S.   +5 more
europepmc   +1 more source

Serine carboxypeptidases of Triatoma brasiliensis (Hemiptera, Reduviidae): Sequence characterization, expression pattern and activity localization

, 2014
Using specific oligonucleotides, 50- and 30-RACE and sequencing, two cDNAs encoding serine carboxypeptidases (tbscp-1 and tbscp-2) from the midgut of the blood sucking heteropteran Triatoma brasiliensis were identified.
Waniek, Peter J, Momoli, Marisa M, Araújo, Catarina A. C, Azambuja, Patricia, Genta, Fernando A, Jansen, Ana Maria   +5 more
core  

Prognostic, diagnostic and therapeutic value of the cancer tubulin code. [PDF]

Cancer Metastasis Rev
Vilela C, Gomes-Andrade D, Silva S, Maiato H.   +3 more
europepmc   +1 more source

Chemoproteomic Elucidation of β-Lactam Drug Targets in <i>Mycobacterium abscessus</i>. [PDF]

ACS Infect Dis
Devlin KL, Hutchinson E, Leach DT, Gorham LJ, Nelson WC, Lamichhane G, Lin VS, Beatty KE.   +7 more
europepmc   +1 more source

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids

The posttranslational modification of carboxy-terminal tails of tubulin plays an important role in the regulation of the microtubule cytoskeleton. Enzymes responsible for deglutamylating tubulin have been discovered within a novel family of mammalian ...
Seixas, Cecilia, Moutin, Marie-Jo, Tanco, Sebastián Martín, Andrieux, Annie, Avilés, Francesc X., Bosc, Christophe, Lorenzo Rivera, Julia, Bièche, Ivan, Rocha, Cecilia, Tort Regàs, Olívia, Janke, Carsten   +10 more
core  

Multilevel Regulation of Peptidoglycan Dynamics in Bacteria: From Molecular Mechanisms to Applied Perspectives. [PDF]

Biomolecules
Dong C, Lu J, Xie L, Wu H, Qiao J.
europepmc   +1 more source