Results 51 to 60 of about 6,236 (183)

Genetic interaction mapping reveals functional relationships between peptidoglycan endopeptidases and carboxypeptidases.

PLoS Genetics
Peptidoglycan (PG) is the main component of the bacterial cell wall; it maintains cell shape while protecting the cell from internal osmotic pressure and external environmental challenges.
Manuela Alvarado Obando, Diego Rey-Varela, Felipe Cava, Tobias Dörr   +3 more
doaj   +1 more source

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids [PDF]

, 2014
International audienceThe posttranslational modification of carboxy-terminal tails of tubulin plays an important role in the regulation of the microtubule cytoskeleton.
Seixas, Cecilia, Tort, Olivia, Lorenzo Rivera, Julia, Bièche, Ivan, Avilés, Francesc Xavier, Janke, Carsten, Tort Regàs, Olívia, Moutin, Marie-Jo, Tanco, Sebastián Martín, Andrieux, Annie, Bosc, Christophe, Tanco, Sebastián, Rocha, Cecilia, Lorenzo, Julia, Moutin, Marie Jo   +14 more
core   +1 more source

Current Advances in Ochratoxin A-Degrading Enzymes [PDF]

Shipin Kexue
Ochratoxin A (OTA) poses a serious threat to human and animal health as well as the ecological environment due to its high toxicity, stable physicochemical properties, and widespread occurrence in food and feed.
NIU Zehui, LIANG Zhihong
doaj   +1 more source

Peptide inhibitors of Streptomyces DD-carboxypeptidases [PDF]

, 1973
peer reviewed1. Peptides that inhibit the dd-carboxypeptidases from Streptomyces strains albus G and R61 were synthesized. They are close analogues of the substrates of these enzymes.
Ghuysen, Jean-Marie, Leyh-Bouille, Mélina, Nieto, Manuel, Frère, Jean-Marie, Perkins, Harnold R.   +4 more
core   +1 more source

Cloning and characterization of the first serine carboxypeptidase from a plant parasitic nematode, Radopholus similis

Scientific Reports, 2017
Radopholus similis is an important parasitic nematode of plants. Serine carboxypeptidases (SCPs) are peptidases that hydrolyse peptides and proteins and play critical roles in the development, invasion, and pathogenesis of certain parasitic nematodes and
Xin Huang, Chun-Ling Xu, Wan-Zhu Chen, Chun Chen, Hui Xie   +4 more
doaj   +1 more source

In vivo effects of bradykinin B2 receptor agonists with varying susceptibility to peptidases.

Frontiers in Pharmacology, 2016
We reported evidence of bradykinin (BK) regeneration from C-terminal extended BK sequences that behave as peptidase-activated B2 receptor (B2R) agonists.
Mélissa eJean, Lajos eGera, Xavier eCharest-Morin, François eMarceau, Hélène eBachelard   +4 more
doaj   +1 more source

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.

PLoS Pathogens, 2020
Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics.
Federica Giordani, Daniel Paape, Isabel M Vincent, Andrew W Pountain, Fernando Fernández-Cortés, Eva Rico, Ning Zhang, Liam J Morrison, Yvonne Freund, Michael J Witty, Rosemary Peter, Darren Y Edwards, Jonathan M Wilkes, Justin J J van der Hooft, Clément Regnault, Kevin D Read, David Horn, Mark C Field, Michael P Barrett   +18 more
doaj   +1 more source

Digestive Enzymes of the Crustaceans Munida and Their Application in Cheese Manufacturing: A Review

Marine Drugs, 2011
Crustaceans Munida (fam. Galatheideae, ord. Decapodi) were fished in the Southern Adriatic Sea and their proteolytic activities were characterized and tested for potential application in cheese manufacturing.
Rocco Rossano, Marilena Larocca, Paolo Riccio   +2 more
doaj   +1 more source

Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen.

Journal of Biological Chemistry, 1994
A novel basic carboxypeptidase clearly different from carboxypeptidase N has been isolated from human plasma. It circulates as an enzymatically inactive precursor enzyme bound to plasminogen. During fibrinolysis, it can be converted to its active form, carboxypeptidase U, through the action of plasmin. The active enzyme has an apparent molecular weight
Wang, W., Hendriks, D., Scharpe, S.
openaire   +3 more sources

Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica).

PLoS ONE, 2019
Efficient communication between cells requires the ability to process precursor proteins into their mature and biologically active forms, prior to secretion into the extracellular space. Eukaryotic cells achieve this via a suite of enzymes that involve a
Michael J Hammond, Tianfang Wang, Scott F Cummins   +2 more
doaj   +1 more source