Results 11 to 20 of about 385,377 (294)
Pathways of Colorectal Carcinogenesis.
Gastroenterology, 2020 Colorectal cancer is a heterogeneous disease that develops via stepwise accumulation of well-characterized genetic and epigenetic alterations. We review the genetic changes associated with the development of pre-cancerous colorectal adenomas and their ...
L. Nguyen, A. Goel, D. Chung
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Circular RNA circSATB2 promotes progression of non-small cell lung cancer cells
Molecular Cancer, 2020 Background Lung cancer has high morbidity and mortality worldwide with non-small cell lung cancer (NSCLC) accounting for 85% of the cases. Therapies for lung cancer have relatively poor outcomes and further improvements are required.
Nan Zhang +10 more
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Cancer Discovery, 2020 Regulatory T cells (Tregs) are abundant ion human and mouse pancreatic cancer. To understand the contribution to the immunosuppressive microenvironment, we depleted Tregs in a mouse model of pancreatic cancer. Contrary to our expectations, Treg depletion
Yaqing Zhang +22 more
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The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis
Molecular Cancer, 2020 Liver cancer is a common cancer worldwide. Although the etiological factors of liver carcinogenesis are well defined, the underlying molecular mechanisms remain largely elusive.
Mengnuo Chen, Chun‐Ming Wong
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Molecular Cancer, 2019 Circular RNAs are widely expressed in eukaryotic cells and associated with cancer. However, limited studies to date have focused on the potential role of circRNAs in progression of lung cancer.
Lijian Chen +10 more
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Concentration and isolation of DNA from biological fluids by agarose gel isotachophoresis
BioTechniques, 2005 Isotachophoresis is an electrophoretic method of separation of charged substances. The method is characterized by a discontinuous buffer system, constant velocity of separated molecules, and the distribution of separated components in the form of narrow ...
Valentina N. Kondratova +3 more
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Nature Communications, 2023 The SWI/SNF ATP-dependent chromatin remodeler is a master regulator of the epigenome, controlling pluripotency and differentiation. Towards the C-terminus of the catalytic subunit of SWI/SNF is a motif called the AT-hook that is evolutionary conserved ...
Dhurjhoti Saha +13 more
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EGFR Activation and Ultraviolet Light-Induced Skin Carcinogenesis
BMC Bioinformatics, 2006 BackgroundSelection of relevant genes for sample classification is a common task in most gene expression studies, where researchers try to identify the smallest possible set of genes that can still achieve good predictive performance (for instance, for ...
R. Díaz-Uriarte, S. Á. D. Andrés
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EJC Supplements, 2015 Glucocorticoids (GCs) are the most important component of therapy for a number of diseases including combined chemotherapy of hematological malignancies. However, their application is strongly restricted by the development of serious side effects as well
L. Tilova +8 more
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Metals and Molecular Carcinogenesis.
Carcinogenesis, 2020 Many metals are essential for living organisms, but at higher doses they may be toxic and carcinogenic. Metal exposure occurs mainly in occupational settings and environmental contaminations in drinking water, air pollution and foods, which can result in
Yusha Zhu, Max Costa
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