Results 21 to 30 of about 385,377 (294)

LINC01137/miR-186-5p/WWOX: a novel axis identified from WWOX-related RNA interactome in bladder cancer

Frontiers in Genetics, 2023
Introduction: The discovery of non-coding RNA (ncRNA) dates back to the pre-genomics era, but the progress in this field is still dynamic and leverages current post-genomics solutions.
Damian Kołat, Żaneta Kałuzińska-Kołat, Katarzyna Kośla, Magdalena Orzechowska, Elżbieta Płuciennik, Andrzej K. Bednarek   +5 more
doaj   +1 more source

Diet and carcinogenesis [PDF]

Carcinogenesis, 1993
In summary there is a wealth of information on dietary and nutritional effects on carcinogenesis in laboratory rodents. Experimental studies based on epidemiological evidence, earlier experimental studies and known or predicted cellular, biochemical and molecular effects of nutrients have produced clear evidence that carcinogenesis in laboratory ...
John D. Groopman, Adrianne E. Rogers, Steven H. Zeisel   +2 more
openaire   +2 more sources

Review of hepatocellular carcinoma: Epidemiology, etiology, and carcinogenesis

Journal of Carcinogenesis, 2017
Since the 1970s, the epidemic of hepatocellular carcinoma (HCC) has spread beyond the Eastern Asian predominance and has been increasing in Northern hemisphere, especially in the United States (US) and Western Europe.
Yezaz A Ghouri, Idrees Mian, J. Rowe
semanticscholar   +1 more source

A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer

Scientific Reports, 2021
Resistance to drugs targeting the androgen receptor (AR) signaling axis remains an important challenge in the treatment of prostate cancer patients. Activation of alternative growth pathways is one mechanism used by cancer cells to proliferate despite ...
Sander A. L. Palit, Jeroen van Dorp, Daniel Vis, Cor Lieftink, Simon Linder, Roderick Beijersbergen, Andries M. Bergman, Wilbert Zwart, Michiel S. van der Heijden   +8 more
doaj   +1 more source

Vasculogenic mimicry in carcinogenesis and clinical applications

Journal of Hematology & Oncology, 2020
Distinct from classical tumor angiogenesis, vasculogenic mimicry (VM) provides a blood supply for tumor cells independent of endothelial cells. VM has two distinct types, namely tubular type and patterned matrix type.
Qingxi Luo, Jun Wang, Wenyuan Zhao, Zhenzi Peng, Xianyu Liu, Bin Li, Heng Zhang, B. Shan, Chunfang Zhang, Chaojun Duan   +9 more
semanticscholar   +1 more source

M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway

World Journal of Surgical Oncology, 2018
Background M2-polarized macrophages are tumor-associated-macrophages (TAMs), which are important contents of tumor-infiltrating immune cells. Toll-like receptor 4 (TLR4) is a molecular biomarker of tumor aggressiveness and poor prognosis.
Rong-Rong Yao, Jing-Huan Li, Rui Zhang, Rong-Xin Chen, Yan-Hong Wang   +4 more
doaj   +1 more source

Circular RNA 406961 interacts with ILF2 to regulate PM2.5-induced inflammatory responses in human bronchial epithelial cells via activation of STAT3/JNK pathways

Environment International, 2020
Fine particulate matter (PM2.5) has been verified to augmented the incidence of pneumonia, asthma, pulmonary fibrosis, and other pulmonary diseases. Airway inflammation is the pathological basis of the respiratory system, and understanding the molecular ...
Yangyang Jia, Xin Li, Aruo Nan, Nan Zhang, Lijian Chen, Hanyu Zhou, Han Zhang, Miaoyun Qiu, Jialu Zhu, Yihui Ling, Yiguo Jiang   +10 more
doaj   +1 more source

X or Y Cancer: An Extensive Analysis of Sex Differences in Lung Adenocarcinoma

Current Oncology, 2023
Background: Cellular metabolism is a tightly controlled process during which cell growth and survival are maintained. Lung cancer is a disease with clear sex differences, where female patients have better survival rates than males.
Raneem Yaseen Hammouz, Magdalena Orzechowska, Dorota Anusewicz, Andrzej K. Bednarek   +3 more
doaj   +1 more source

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

Carcinogenesis, 2016
Summary By reversing emphasis from precursor uptake to product accumulation and release, we posit that lactate production (‘lactagenesis’) supports carcinogenesis and it is the explanation and purpose of the Warburg effect.
Iñigo San-Millán, G. Brooks
semanticscholar   +1 more source

Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity

Biological Research, 2019
Background Recent evidences indicated that some local anaesthetic agents played a role in inhibiting the proliferation of cancer cells; Whether ropivacaine is able to promote apoptosis of hepatocellular carcinoma (HCC) cells is still unclear.
Wenting Wang, Mingyue Zhu, Zhixin Xu, Wei Li, Xu Dong, Yi Chen, Bo Lin, Mengsen Li   +7 more
doaj   +1 more source