Results 21 to 30 of about 285,650 (298)

T25

EJC Supplements, 2015
Glucocorticoids (GCs) are widely used in treatment of many cancer types due to its ability to induce apoptosis in malignant cells in blood cancer therapy, and to prevent nausea, emesis and chemotherapy-associated hepatotoxicity in case of solid tumors ...
E. Lesovaya, L. Tilova, O. Zadorozhnaya, A. Savinkova, K. Kirsanov, A. Ogloblina, G. Belitsky, G. Baida, I. Budunova, M. Yakubovskaya   +9 more
doaj   +1 more source

Cadmium carcinogenesis [PDF]

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2003
Cadmium is a heavy metal of considerable environmental and occupational concern. Cadmium compounds are classified as human carcinogens by several regulatory agencies. The most convincing data that cadmium is carcinogenic in humans comes from studies indicating occupational cadmium exposure is associated with lung cancer.
openaire   +3 more sources

Barretts's carcinogenesis [PDF]

Pathology International, 2019
Barrett's esophagus is considered a precancerous lesion of esophageal adenocarcinoma (EAC). Long‐segment Barrett's esophagus, which is generally associated with intestinal metaplasia, has a higher rate of carcinogenesis than short‐segment Barrett's esophagus, which is mainly composed of cardiac‐type mucosa.
Ryoji Kushima, Shunpei Kanai, Ken-ichi Mukaisho, Takahisa Nakayama, Takanori Hattori, Hiroyuki Sugihara   +5 more
openaire   +3 more sources

Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

Genome Medicine, 2021
An amendment to this paper has been published and can be accessed via the original article.
Tonći Šuštić, Sake van Wageningen, Evert Bosdriesz, Robert J. D. Reid, John Dittmar, Cor Lieftink, Roderick L. Beijersbergen, Lodewyk F. A. Wessels, Rodney Rothstein, René Bernards   +9 more
doaj   +1 more source

Molecular landscapes of glioblastoma cell lines revealed a group of patients that do not benefit from WWOX tumor suppressor expression

Frontiers in Neuroscience, 2023
IntroductionGlioblastoma (GBM) is notorious for its clinical and molecular heterogeneity, contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor suppressor genes important in nervous tissue or related pathologies, which was ...
Żaneta Kałuzińska-Kołat, Damian Kołat, Katarzyna Kośla, Elżbieta Płuciennik, Andrzej K. Bednarek   +4 more
doaj   +1 more source

Apoptosis and carcinogenesis [PDF]

British Medical Bulletin, 1997
Many tumours are characterised by increased levels of apoptosis. This observation establishes significance for this process in tumour development, but it does little to elucidate the nature of this role, nor does it yield information relevant to the early stages of carcinogenesis.
Alan R Clarke, Scott K Lyons
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

RUBIC identifies driver genes by detecting recurrent DNA copy number breaks

Nature Communications, 2016
Analysis of cancer genome sequencing data has been used to predict genes associated with the pathogenesis of cancer. Here, the authors propose a new algorithm entitled RUBIC that predicts breaks in DNA as opposed to previously published methods that ...
Ewald van Dyk, Marlous Hoogstraat, Jelle ten Hoeve, Marcel J. T. Reinders, Lodewyk F. A. Wessels   +4 more
doaj   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

NRAS destines tumor cells to the lungs

EMBO Molecular Medicine, 2017
The lungs are frequently affected by cancer metastasis. Although NRAS mutations have been associated with metastatic potential, their exact role in lung homing is incompletely understood.
Anastasios D Giannou, Antonia Marazioti, Nikolaos I Kanellakis, Ioanna Giopanou, Ioannis Lilis, Dimitra E Zazara, Giannoula Ntaliarda, Danai Kati, Vasileios Armenis, Georgia A Giotopoulou, Anthi C Krontira, Marina Lianou, Theodora Agalioti, Malamati Vreka, Maria Papageorgopoulou, Sotirios Fouzas, Dimitrios Kardamakis, Ioannis Psallidas, Magda Spella, Georgios T Stathopoulos   +19 more
doaj   +1 more source