Results 71 to 80 of about 28,766 (211)

APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy. [PDF]

, 2019
Tumor-associated neo-antigens are mutated peptides that allow the immune system to recognize the affected cell as foreign. Cells carrying excessive mutation load often develop mechanisms of tolerance.
Boichard, Amélie, Frampton, Garrett M, Goodman, Aaron, Kurzrock, Razelle, Lippman, Scott, Pham, Timothy V, Tamayo, Pablo, Tsigelny, Igor F, Yeerna, Huwate   +8 more
core  

Skin Cancer Predisposition Genes, Full‐Body Skin Examinations, Familial Disclosure, and Genetic Testing Among High‐Risk Individuals

International Journal of Dermatology, EarlyView.
ABSTRACT Background There is a lack of knowledge in full‐body skin examinations (FBSEs) in the context of pathogenic or likely pathogenic variants (PV/LPV) in skin cancer predisposition genes (CPGs). This study assessed the association between carrier status of PV/LPV in skin CPGs and FBSEs and described the patterns of family letter receipt, familial ...
Jincong Q. Freeman, Yu Matsui, Fangyuan Zhao, Olufunmilayo I. Olopade, Dezheng Huo   +4 more
wiley   +1 more source

Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. [PDF]

, 2005
BACKGROUND: Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.
Bosch, J, Burroughs, AK, Escorsell, A, Gao, H, Garcia-Pagan, JC, Garcia-Tsao, G, Grace, ND, Groszmann, RJ, Makuch, R, Matloff, DS, Patch, D, Planas, R, Portal Hypertension Collaborative Group   +12 more
core   +1 more source

Sirolimus for Secondary Prevention of Cutaneous Squamous Cell Carcinoma in Kidney Transplant Recipients: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

International Journal of Dermatology, EarlyView.
Meta‐analysis of randomized controlled trials shows that switching from calcineurin inhibitors (CNI) to sirolimus in kidney transplant recipients (KTRs) with prior cutaneous squamous cell carcinoma (cSCC) reduces secondary cSCC incidence but increases adverse‐event–related treatment discontinuation.
Yannick Foerster, Julia Palaras, Kristine Mayer, Tilo Biedermann, Oana‐Diana Persa   +4 more
wiley   +1 more source

Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]

, 2012
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS, Jagtap, SV, Khirsagar, AY, Nikumbh, DB, S, Khan   +4 more
core  

Survey of KI, WU, MW and STL polyomavirus in cancerous and non-cancerous lung tissues [PDF]

, 2018
K
Bidiga, László, Csoma, Eszter, Gergely, Lajos, Katona, Melinda, Méhes, Gábor   +4 more
core   +1 more source

US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett’s Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends

JMIR Dermatology
Through Jimmy Buffett’s unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as ...
Macy Haight, Hayden R Jacobs, Sarah K Boltey, Kelly A Murray, Micah Hartwell   +4 more
doaj   +1 more source

Merkel cell distribution in the human eyelid

European Journal of Histochemistry, 2013
Although Merkel cell carcinoma of the eye lid is reported frequently in the literature, only limited information exists about the distribution of Merkel cells in this tissue.
C.A. May, I. Osterland
doaj   +1 more source

Immunoglobulins to mitigate paraneoplastic Lambert Eaton Myasthenic Syndrome under checkpoint inhibition in Merkel cell carcinoma

Neurological Research and Practice, 2020
Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the immune system for tumor antigens.
Maike F. Dohrn, Ulrike Schöne, Charlotte Küppers, Deborah Christen, Jörg B. Schulz, Burkhard Gess, Simone Tauber   +6 more
doaj   +1 more source

Preclinical evaluation of NF-kappa B-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination [PDF]

, 2017
Background: Merkel cell carcinoma (MCC) is a rare but very aggressive skin tumor that develops after integration of a truncated form of the large T-antigen (truncLT) of the Merkel cell polyomavirus (MCV) into the host’s genome.
Doerrie, Jan, Erdmann, Michael, Gerer, Kerstin F., Hadrup, Sine Reker, Hoyer, Stefanie, Lyngaa, Rikke Birgitte, Martin, Lena-Marie, Schaft, Niels, Schuler, Gerold, Schuler-Thurner, Beatrice, Voll, Reinhard E.   +10 more
core   +2 more sources