Results 201 to 210 of about 213,511 (352)
Opportunistic Screening for Pancreatic Cancer using Computed Tomography Imaging and Radiology Reports [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer, with most cases diagnosed at stage IV and a five-year overall survival rate below 5%. Early detection and prognosis modeling are crucial for improving patient outcomes and guiding early intervention strategies.
arxiv
Targeting Mesothelin in Pancreatic Ductal Adeno- Carcinoma PDAC [PDF]
Gilles Pagès, Christopher Montemagno
openaire +2 more sources
Small‐Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation
The development of the KRAS G12C inhibitor sotorasib was a major advance towards drugging KRAS. However, the G12C mutation is only found in about 10% of tumors with a KRAS mutation. KRAS tyrosine amino acids could provide alternative sites for covalent drug development.
Alexander Landgraf+5 more
wiley +1 more source
Pankreaskarzinom (duktales Adenokarzinom)
Lorenzo Käser+2 more
openaire +3 more sources
Delivery of Natural Small Molecules Through Nanocarriers for Cancer Treatment
Natural small molecules through nanocarriers for cancer treatment ABSTRACT Cancer is a formidable adversary, accounting for the second highest number of fatalities worldwide. A multitude of studies have indicated that naturally sourced small‐molecule compounds, owing to their low toxicity and multi‐target capabilities, significantly aid in the fight ...
Fangting Ye+7 more
wiley +1 more source
Pancreatic Metastasis from Invasive Ductal Carcinoma of the Breast [PDF]
Yunsuk Choi+6 more
openaire +1 more source
Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors
Cytokeratin 13 (CK13) is a type I acidic low molecular weight cytokeratin, which is mainly expressed in urothelium and in the squamous epithelium of various sites of origin. Loss of CK13 has been implicated in the development and progression of squamous epithelial neoplasms. To comprehensively determine CK13 expression in normal and neoplastic tissues,
Maximilian Lennartz+25 more
wiley +1 more source
Exosomes, autophagy, and cancer: A complex triad
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés+2 more
wiley +1 more source