Differential accumulation of cardenolides from Asclepias curassavica by large milkweed bugs does not correspond to availability in seeds or biological activity on the bug Na+/K+-ATPase [PDF]
Frontiers in Ecology and Evolution, 2023 Milkweed–herbivore systems are characterized by cardenolide chemical defenses and specialized herbivore adaptations such as physiological target site insensitivity.
Paola Rubiano-Buitrago +6 more
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New CNS depressant cardenolide glycoside from the roots of Nerium oleander
Results in Chemistry, 2020 A new central nervous system (CNS) depressant cardenolide glycoside named nerioleanderoside (1) was isolated from active n-butanol fraction of the aqueous- ethanolic (5:95 v/v) extract of the fresh dried roots of Nerium oleander.
Ghanshyam Tiwari +3 more
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Aphid Resistance Segregates Independently of Cardenolide and Glucosinolate Content in an Erysimum cheiranthoides (Wormseed Wallflower) F2 Population [PDF]
PlantsPlants in the genus Erysimum produce both glucosinolates and cardenolides as a defense mechanism against herbivory. Two natural isolates of Erysimum cheiranthoides (wormseed wallflower) differed in their glucosinolate content, cardenolide content, and ...
Mahdieh Mirzaei +5 more
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Frontiers in Plant Science, 2018 A major prediction of coevolutionary theory is that plants may target particular herbivores with secondary compounds that are selectively defensive.
Georg Petschenka +5 more
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New Structures, Spectrometric Quantification, and Inhibitory Properties of Cardenolides from Asclepias curassavica Seeds [PDF]
Molecules, 2022 Cardiac glycosides are a large class of secondary metabolites found in plants. In the genus Asclepias, cardenolides in milkweed plants have an established role in plant–herbivore and predator–prey interactions, based on their ability to inhibit the ...
Paola Rubiano-Buitrago +3 more
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Chemoenzymatic synthesis of the cardenolide rhodexin A and its aglycone sarmentogenin [PDF]
Beilstein Journal of Organic ChemistryHerein, we report a concise chemoenzymatic synthesis of the cardenolide rhodexin A in 9 steps and the first protecting-group-free synthesis of its aglycone sarmentogenin in 7 steps from 17-deoxycortisone. The synthesis features a scalable enzymatic C14–H
Fuzhen Song +4 more
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Thevetia thevetioides Cardenolide and Related Cardiac Glycoside Profile in Mature and Immature Seeds by High-Resolution Thin-Layer Chromatography (HPTLC) and Quadrupole Time of Flight–Tandem Mass Spectrometry (Q-TOF MS/MS) Reveals Insights of the Cardenolide Biosynthetic Pathway [PDF]
MoleculesThevetia thevetioides is a species within the Apocynaceae family known for containing cardenolide-glycosides, commonly referred to as cardiac glycosides, which are characteristic of this genus.
Juan Vázquez-Martínez +2 more
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Strophanthus sarmentosus Extracts and the Strophanthus Cardenolide Ouabain Inhibit Snake Venom Proteases from Echis ocellatus [PDF]
MoleculesStrophanthus sarmentosus is recognised for various ethnomedicinal applications, including treatment after snakebites. However, only limited scientific evidence exists on its antivenomous capabilities.
Julius Abiola +4 more
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Fecal Deployment: An Alternative Way of Defensive Host Plant Cardenolide Use by Lilioceris merdigera Larvae. [PDF]
J Chem Ecol, 2023 Baum M, Dobler S.
europepmc +3 more sources
Substrate Specificity of ABCB Transporters Predicted by Docking Simulations Can Be Confirmed by Experimental Tests [PDF]
MoleculesATP-binding cassette (ABC) transporters, particularly those of subfamily B, are involved in cell detoxification, multidrug resistance, drug treatment pharmacodynamics, and also ecological adaptation.
Mario Röpcke +5 more
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