Results 21 to 30 of about 2,274 (220)

Relative Selectivity of Plant Cardenolides for Na+/K+-ATPases From the Monarch Butterfly and Non-resistant Insects

Frontiers in Plant Science, 2018
A major prediction of coevolutionary theory is that plants may target particular herbivores with secondary compounds that are selectively defensive.
Georg Petschenka, Colleen S. Fei, Juan J. Araya, Susanne Schröder, Barbara N. Timmermann, Anurag A. Agrawal   +5 more
doaj   +1 more source

High-resolution tandem mass spectrometry dataset reveals fragmentation patterns of cardiac glycosides in leaves of the foxglove plants

Data in Brief, 2020
Cardiac glycosides, steroid derivatives extracted from the foxglove plants, have been used for the treatment of heart failure since the 18th century. A method based on liquid chromatography coupled with high-resolution tandem mass spectrometry (LC/MS2 ...
Baradwaj Gopal Ravi, Mary Grace E. Guardian, Rebecca Dickman, Zhen Q. Wang   +3 more
doaj   +1 more source

Arbuscular mycorrhizal fungi alter above- and below-ground chemical defense expression differentially among Asclepias species

Frontiers in Plant Science, 2013
Belowground symbionts of plants can have substantial influence on plant growth and nutrition. Recent work demonstrates that mycorrhizal fungi can affect plant resistance to herbivory and the performance of above and belowground herbivores. Although these
Rachel L Vannette, Rachel L Vannette, Mark D. Hunter, Sergio eRasmann   +3 more
doaj   +1 more source

Tests of the coupled expression of latex and cardenolide plant defense in common milkweed (Asclepias syriaca) [PDF]

, 2014
The coexpression of plant resistance traits suggests the hypothesis that they may have complementary functions in defense against herbivory. To address the extent to which defensive traits are necessarily coupled in plants grown under various conditions,
Patrick, Eamonn T., Hastings, Amy P., Agrawal, Anurag A.   +2 more
core   +1 more source

New Cardenolides from Biotransformation of Gitoxigenin by the Endophytic Fungus Alternaria eureka 1E1BL1: Characterization and Cytotoxic Activities

Molecules, 2021
Microbial biotransformation is an important tool in drug discovery and for metabolism studies. To expand our bioactive natural product library via modification and to identify possible mammalian metabolites, a cytotoxic cardenolide (gitoxigenin) was ...
Erdal Bedir, Çiğdem Karakoyun, Gamze Doğan, Gülten Kuru, Melis Küçüksolak, Hasan Yusufoğlu   +5 more
doaj   +1 more source

A Novel Cardenolide Glycoside Isolated from Xysmalobium undulatum Reduces Levels of the Alzheimer’s Disease-Associated β-Amyloid Peptides Aβ42 In Vitro

Pharmaceuticals, 2021
Elevated levels of the amylo β-proteins (Aβ), particularly Aβ42, are associated with a high risk of Alzheimer’s disease (AD). The Aβ proteins are produced from cellular processing of the amyloid precursor proteins (APPs).
Anuradha Thakur, Phanankosi Moyo, Carl Johan van der Westhuizen, Hyun Ok Yang, Vinesh Maharaj   +4 more
doaj   +1 more source

Less Is More: a Mutation in the Chemical Defense Pathway of Erysimum cheiranthoides (Brassicaceae) Reduces Total Cardenolide Abundance but Increases Resistance to Insect Herbivores

, 2020
Erysimum cheiranthoides L (Brassicaceae; wormseed wallflower) accumulates not only glucosinolates, which are characteristic of the Brassicaceae, but also abundant and diverse cardenolides.
Hastings, Amy P., Mirzaei, Mahdieh, Alani, Martin L., Younkin, Gordon C., Jander, Georg, Züst, Tobias, Agrawal, Anurag A.   +6 more
core   +1 more source

Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu, Yo Matsumoto, Koichi Hagiwara, Masayuki Inoue   +3 more
wiley   +2 more sources

Molluscicidal Activity of Methomyl and Cardenolide Extracts from <em>Calotropis procera</em> and <em>Adenium</em> <em>arabicum</em> Against the Land Snail <em>Monacha cantiana</em>

Molecules, 2012
In this work, we have evaluated the molluscicidal activity of two cardenolide extracts from <em>Adenium arabicum</em> Balf f. [the benzene (B) and methanol (M) extracts], one cardenolide extract from <em>Calotropis procera</em> ...
Alaa Bayoumi, Yasser Abobakr, Hamdy Hussein, Ali Al-Sarar   +3 more
doaj   +1 more source

Host plant specificity of the monarch butterfly Danaus plexippus: A systematic review and meta-analysis.

PLoS ONE, 2022
The preference-performance hypothesis explains host specificity in phytophagous insects, positing that host plants chosen by adults confer the greatest larval fitness. However, adults sometimes oviposit on plants supporting low larval success because the
Lewis Greenstein, Christen Steele, Caz M Taylor   +2 more
doaj   +2 more sources