Results 11 to 20 of about 3,494 (200)
Strophanthus sarmentosus Extracts and the Strophanthus Cardenolide Ouabain Inhibit Snake Venom Proteases from Echis ocellatus [PDF]
MoleculesStrophanthus sarmentosus is recognised for various ethnomedicinal applications, including treatment after snakebites. However, only limited scientific evidence exists on its antivenomous capabilities.
Julius Abiola +4 more
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Total Synthesis of Cardenolides Acospectoside A and Acovenoside B [PDF]
MoleculesAcospectoside A (1) and acovenoside B (2), two cytotoxic cardenolides extracted from the venomous South African bush Acokanthera oppositifolia, are distinguished by their unique structural motifs of the l-acovenose moiety at C-3 and a 1β-O-acetylated ...
Benzhang Liu, Peng Xu, Biao Yu
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Frontiers in Pharmacology, 2021 Cardenolide glycosides are natural compounds known to inhibit the ion pumping function of the Na+/K+-ATPase in cellular systems. Interestingly, various cancer cell types are highly susceptible to cardenolide glycosides. Herein, we explore the cardenolide
Susanne Hafner +2 more
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Frontiers in Ecology and Evolution, 2023 Milkweed–herbivore systems are characterized by cardenolide chemical defenses and specialized herbivore adaptations such as physiological target site insensitivity.
Paola Rubiano-Buitrago +6 more
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Gut-specific cardenolide-resistant sodium pump primed an omnivore to feed on toxic oleander
iScience, 2022 Summary: Apocynaceae plants produce toxic cardenolides to defend against their herbivores. Cardenolides could inhibit the α subunit of Na+⁄K+-ATPase (ATPα), which plays critical roles in biological processes such as muscle contraction, neural function ...
Tianyu Wang, Lina Shi, Ying Zhen
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Characterization and Chromatographic Fingerprint Analysis of Traditional Wallflower Oil [PDF]
Research Journal of Pharmacognosy, 2021 Background and objective: Wallflower oil is made from the flowers of Erysimum cheiri (L.) Crantz which is a herb rich in cardenolide compounds. Wallflower oil was traditionally indicated for analgesic, anti-inflammatory, hair tonic, and wound healing ...
Ghazaleh Mosleh +2 more
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Ecology and Evolution, 2021 Sequestration, that is, the accumulation of plant toxins into body tissues for defense, was predicted to incur physiological costs and may require resistance traits different from those of non‐sequestering insects.
Prayan Pokharel +2 more
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G3: Genes, Genomes, Genetics, 2018 Calotropis gigantea produces specialized secondary metabolites known as cardenolides, which have anticancer and antimalarial properties. Although transcriptomic studies have been conducted in other cardenolide-producing species, no nuclear genome ...
Genevieve M. Hoopes +6 more
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Effects of soil nutrients on the sequestration of plant defence chemicals by the specialist insect herbivore, Danaus plexippus [PDF]
, 2015 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110863/1/een12168 ...
Agrawal +51 more
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Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle. [PDF]
PLoS ONE, 2014 In the past decade, there has been a profound increase in the number of studies revealing that cardenolide glycosides display inhibitory activity on the growth of human cancer cells.
Wohn-Jenn Leu +7 more
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