Results 41 to 50 of about 1,572 (155)
Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Plant Biotechnology Journal, Volume 24, Issue 1, Page 328-345, January 2026.Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat +6 more
wiley +1 more source
Molecules, 2022 Pergularia tomentosa L., a milkweed tropical plant belonging to the family Asclepiadaceae, is a rich source of unusual cardiac glycosides, characterised by transfused A/B rings and a sugar moiety linked by a double link, generating a dioxanoid structure.
Stefania Martucciello +8 more
doaj +1 more source
The Scientific World Journal, Volume 2026, Issue 1, 2026.Mallotus paniculatus (Lam.), a member of the Euphorbiaceae Juss family, is a little tree or shrub that has long been used in folk medicine to cure ailments like fever, wound healing, and postpartum recuperation. In this study, Swiss albino mice were used to evaluate the analgesic, antipyretic, and antidiarrheal properties of the acetone extract of M ...
Md. Jahirul Islam Mamun +9 more
wiley +1 more source
Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells
Cell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros +3 more
wiley +1 more source
Heliyon, 2022 Cardenolides, a group of cardiac glycosides are potent inhibitors of Na+/K+ ATPase pump in mammals, animals including insects. Some insects can circumvent the toxicity of cardenolides by mechanisms like target site resistance and metabolic resistance ...
Krishnamanikumar Premachandran +1 more
doaj +1 more source
Host plants and experimental warming impact fitness and infection outcomes in a migratory butterfly
Ecological Entomology, Volume 50, Issue 6, Page 1159-1171, December 2025.Host plant species interacted with temperature treatment to shape monarch survival and infection probabilities. Temperature modified the expected role of tropical milkweed, which did not confer OE resistance to monarchs under elevated temperatures.
Isabella G. Ragonese +5 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2006 Non-small cell lung cancers (NSCLCs) are the leading cause of cancer deaths in most developed countries. Targeting heat shock protein 70 (Hsp70) expression and function, together with the induction of lysosomal membrane permeabilization (LMP), could ...
Tatjana Mijatovic +8 more
doaj +1 more source
Evolutionary Changes of GT1 Provide Insights Into the Adaptation of Butterflies to Plant Feeding
Ecology and Evolution, Volume 15, Issue 11, November 2025.We investigated the evolution of glycosyltransferase 1 (GT1) genes in 69 butterfly species to explore their association with host plant adaptation. Our results reveal frequent tandem duplications and adaptive selection in GT1s, especially in UGT33 and UGT40 subfamilies, alongside expression patterns suggesting functional diversification.
Jinyu Wu +7 more
wiley +1 more source
Honest signalling in predator–prey interactions: Testing the resource allocation hypothesis
Functional Ecology, Volume 39, Issue 10, Page 2833-2848, October 2025.Read the free Plain Language Summary for this article on the Journal blog. Abstract Warning signals are honest if they reliably deliver information about prey unprofitability to predators. One potential mechanism that may create and maintain a positive relationship between the strength of signals and defence is the resource allocation between these ...
Emily Burdfield‐Steel +5 more
wiley +1 more source
Applications in Plant Sciences, Volume 13, Issue 5, September-October 2025.Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Elizabeth Sage Hunter +5 more
wiley +1 more source