Results 41 to 50 of about 2,370 (198)

The function and evolutionary significance of a triplicated Na,K-ATPase gene in a toxin-specialized insect

BMC Evolutionary Biology, 2017
Background The Na,K-ATPase is a vital animal cell-membrane protein that maintains the cell’s resting potential, among other functions. Cardenolides, a group of potent plant toxins, bind to and inhibit this pump.
Jennifer N. Lohr, Fee Meinzer, Safaa Dalla, Renja Romey-Glüsing, Susanne Dobler   +4 more
doaj   +1 more source

Bioactive Compounds from the Plants of the Elaeodendron Genus and Their Biological Activities—A Review

Applied Sciences, 2022
Elaeodendron is a genus of tiny trees, shrubs, vines, and herbs consisting of about 23 species. It is used in traditional medicine and has a wide range of pharmacological activities.
Nambooze Jennifer, Abhay Prakash Mishra, Manisha Nigam, Hari Prasad Devkota, Keshav Raj Paudel, Motlalepula Gilbert Matsabisa   +5 more
doaj   +1 more source

Molluscicidal Activity of Methomyl and Cardenolide Extracts from <em>Calotropis procera</em> and <em>Adenium</em> <em>arabicum</em> Against the Land Snail <em>Monacha cantiana</em>

Molecules, 2012
In this work, we have evaluated the molluscicidal activity of two cardenolide extracts from <em>Adenium arabicum</em> Balf f. [the benzene (B) and methanol (M) extracts], one cardenolide extract from <em>Calotropis procera</em> ...
Alaa Bayoumi, Yasser Abobakr, Hamdy Hussein, Ali Al-Sarar   +3 more
doaj   +1 more source

Cardenolides, toxicity, and the costs of sequestration in the coevolutionary interaction between monarchs and milkweeds

, 2021
International audienceFor highly specialized insect herbivores, plant chemical defenses are often co-opted as cues for oviposition and sequestration.
Duplais, Christophe, Böröczky, Katalin, White, Ron, A, Jiang, Ren-Wang, Haribal, Meena, Agrawal, Anurag, A, Hastings, Amy, P   +6 more
core   +1 more source

Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

Memorias do Instituto Oswaldo Cruz, 1991
The hydroalcoholic extract of the powdered bark of the Indian-snuff Maquira sclerophylla Ducke was purified by column chromatography in silica-gel and the major cardenolide isolated from preparative TLC was identified by 1H-NMR, 1 2 C-NMR and IR analyses.
João Ernesto de Carvalho, Luce Maria Brandão Torres, Antonio José Lapa   +2 more
doaj   +1 more source

Calotropin and corotoxigenin 3-O-glucopyranoside from the desert milkweed Asclepias subulata inhibit the Na+/K+-ATPase activity [PDF]

PeerJ, 2022
Na+/K+-ATPase is an essential transmembrane enzyme found in all mammalian cells with critical functions for cell ion homeostasis. The inhibition of this enzyme by several cardiotonic steroids (CTS) has been associated with the cytotoxic effect on cancer ...
Salvador E. Meneses-Sagrero, Luisa A. Rascón-Valenzuela, Juan C. García-Ramos, Wagner Vilegas, Aldo A. Arvizu-Flores, Rogerio R. Sotelo-Mundo, Ramon E. Robles-Zepeda   +6 more
doaj   +2 more sources

Cardiac Glycosides in Human Physiology and Disease: Update for Entomologists

Insects, 2019
Cardiac glycosides, cardenolides and bufadienolides, are elaborated by several plant or animal species to prevent grazing or predation. Entomologists have characterized several insect species that have evolved the ability to sequester these glycosides in
Rif S. El-Mallakh, Kanwarjeet S. Brar, Rajashekar Reddy Yeruva   +2 more
doaj   +1 more source

Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis

, 2020
[[abstract]]An unprecedented biological function of natural cardenolides independent of their membrane target Na(+)/K(+)-ATPase is disclosed. Previously, we reported that cardenolides impart anti-transmissible gastroenteritis coronavirus (anti-TGEV ...
Yang, CW;Hsu, HY;Chang, HY;Lee, YZ;Lee, SJ
core   +1 more source

Cardenolides data - Experiment 3

, 2014
Chemical analysis of cardenolides in plants, adults, and eggs sampled during experiment ...
Eleanore D. Sternberg (3249555), Mark D. Hunter (2909483), Jacobus C. de Roode (249188)   +2 more
core   +1 more source

Egg Cardenolides - Experiment 1 & 2

, 2014
Chemical analysis of cardenolides in eggs sampled during experiment 1 ...
Eleanore D. Sternberg (3249555), Mark D. Hunter (2909483), Sternberg, Eleanore D., de Roode, Jacobus C., Hunter, Mark D., Jacobus C. de Roode (249188)   +5 more
core   +1 more source