Results 81 to 90 of about 2,772 (212)

Antiproliferative Cardenolides from the Aerial Parts of Pergularia tomentosa

, 2019
The LC-MS analysis of the MeOH extract of the aerial parts of Pergularia tomentosa led to the isolation of 23 compounds, of which the structures were elucidated unambiguously by NMR spectroscopic data analysis. Three new doubly linked cardenolides (4, 13,
Hosseini, Seyed Hamzeh, Masullo, Milena, Piacente, Sonia, Ayyari, Mahdi, Pizza, Cosimo, Cerulli, Antonietta, Martucciello, Stefania   +6 more
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Allamanda cathartica leaves do not contain cardioactive glycosides [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Allamanda cathartica, a plant used in traditional medicine for different purposes, has been considered a cardiotoxic plant. However, the alleged cardiac glycoside was not further studied. Thus, the present study aimed to determine whether the leaves of A.
B.P. Santos, G.P.P. Ataíde, C.J.C. Saraiva, M.S. Teixeira, B. Soto-Blanco   +4 more
doaj   +1 more source

Mechanism of 14β hydroxylation in the biosynthesis of cardenolides: the role of 14β-cholest-5-en-3β-ol

, 1977
The intermediary role of 14β-cholest-5-en-3β-ol in the biosynthesis of cardenolides in Digitalis lanata was excluded.
M. Anastasia, Mario Anastasia, F. Ronchetti, Fiamma Ronchetti   +3 more
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Naturally occurring cardenolides affecting Schistosoma mansoni

, 2020
Schistosomiasis is a neglected tropical disease of considerable public health burden. We recently discovered a micromolar activity of several cardenolides against newly transformed schistosomula (NTS) of the parasitic flatworm; Schistosoma mansoni; in a ...
Cheung, H. T. Andrew, Keiser, Jennifer, Bräse, Stefan, Koch, Vanessa, Deckers, Anke, Jung, Nicole, Keiser J, Deckers A, Cheung HTA, Jung N, Koch V, Bräse S   +11 more
core   +1 more source

Cardenolides are potent inhibitors of RBM20 dependent titin splicing.

, 2018
Figure layout and panels as described in Fig 3. (a, b) Additional cardenolides not present in the original library were selected to evaluate their potency to inhibit RBM20 dependent titin splicing.
Jens-Peter von Kries (5368169), Martin Liss (5368172), Michael H. Radke (5368175), Martin Neuenschwander (680771), Michael Gotthardt (755019), Jamina Eckhard (370592), Vita Dauksaite (5368178)   +6 more
core   +1 more source

The cardenolides ouabain and reevesioside A promote FGF2 secretion and subsequent FGFR1 phosphorylation via converged ERK1/2 activation

, 2020
[[abstract]]Na(+)/K(+)-ATPase alpha1 was reported to directly interact with and recruit FGF2 (fibroblast growth factor 2), a vital cell signaling protein implicated in angiogenesis, to the inner plasma membrane for subsequent secretion.
Zhao, GH;Qiu, YQ;Yang, CW;Chen, IS;Chen, CY;Lee, SJ
core   +1 more source

Investigation of Relationship Between Chemical Stress Factors and Certain Metabolites Including Cardenolides in Callus Cultures of Endemic Turkish Digitalis L. Species

International Journal of Secondary Metabolite, 2017
The aim of the present research is to obtain relationship between different stress treatments [Cu (copper) and Hg (mercury)] and content of cardiac glycosides (digoxigenin, gitoxigenin, lanatoside C, digoxin and digitoxin) as secondary metabolites of ...
Gunce Sahin, Sandeep Kumar Verma, Ekrem Gurel   +2 more
doaj   +1 more source

Arbuscular mycorrhizal fungi alter above- and below-ground chemical defense expression differentially among Asclepias species

Frontiers in Plant Science, 2013
Belowground symbionts of plants can have substantial influence on plant growth and nutrition. Recent work demonstrates that mycorrhizal fungi can affect plant resistance to herbivory and the performance of above and belowground herbivores. Although these
Rachel L Vannette, Rachel L Vannette, Mark D. Hunter, Sergio eRasmann   +3 more
doaj   +1 more source

Does chemistry make a difference? Milkweed butterfly sequestered cardenolides as a defense against parasitoid wasps

, 2019
Plant allelochemicals have important roles in plant defense as well as ecological and co-evolutionary dynamics within tri-trophic systems of plants, herbivores, and natural enemies.
Nail, Kelly R., Oberhauser, Karen S., Meyer, Rebecca A., Zalucki, Myron P., Stenoien, Carl M.   +4 more
core   +1 more source

Pergularia tomentosa, from Traditional Uses to Ecology and Phytochemistry

Journal of Medicinal Plants, 2017
Background: Pergularia tomentosa L. has several traditional uses and biological activities which need to be more investigated. Objective: In this study, some ecological and phytochemical properties of Pergularia tomentosa were assessed.
SH Hosseini Kahnouj, M Ayyari, Hossein Azarnivand, S Piacente, MA Zare Chahouki   +4 more
doaj