Results 11 to 20 of about 511,264 (218)

Il12a Deletion Aggravates Sepsis-Induced Cardiac Dysfunction by Regulating Macrophage Polarization

Frontiers in Pharmacology, 2021
Cardiac dysfunction is a well-recognized complication of sepsis and is associated with the outcome and prognosis of septic patients. Evidence suggests that Il12a participates in the regulation of various cardiovascular diseases, including heart failure ...
Zhen Wang, Zhen Wang, Zhen Wang, Menglin Liu, Di Ye, Di Ye, Di Ye, Jing Ye, Jing Ye, Jing Ye, Menglong Wang, Menglong Wang, Menglong Wang, Jianfang Liu, Jianfang Liu, Jianfang Liu, Yao Xu, Yao Xu, Yao Xu, Jishou Zhang, Jishou Zhang, Jishou Zhang, Mengmeng Zhao, Mengmeng Zhao, Mengmeng Zhao, Yongqi Feng, Yongqi Feng, Yongqi Feng, Shuwan Xu, Shuwan Xu, Shuwan Xu, Wei Pan, Wei Pan, Wei Pan, Zhen Luo, Zhen Luo, Zhen Luo, Dan Li, Jun Wan, Jun Wan, Jun Wan   +40 more
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Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

PLoS Pathogens, 2023
Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance.
Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram   +12 more
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Combination therapy using tafamidis and neurohormonal blockers for cardiac amyloidosis and a reduced ejection fraction: a case report

Journal of International Medical Research, 2022
Cardiac amyloidosis usually presents with diastolic dysfunction, but sometimes systolic dysfunction develops, particularly at its advanced stage. However, the therapeutic strategy for patients with cardiac amyloidosis and systolic dysfunction remains ...
Teruhiko Imamura, Toshihide Izumida, Masakazu Hori, Shuhei Tanaka, Koichiro Kinugawa   +4 more
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Assessment of cardiac function in rat endovascular perforation model of subarachnoid hemorrhage; A model of subarachnoid hemorrhage-induced cardiac dysfunction

Frontiers in Synaptic Neuroscience, 2022
Although the association between cardiac dysfunction and subarachnoid hemorrhage (SAH) has been recognized, its precise underlying mechanism remains unknown. Furthermore, no suitable animal models are available to study this association.
Masahito Munakata, Hideaki Kanazawa, Kensuke Kimura, Takahide Arai, Hiroaki Sukegawa, Keiichi Fukuda   +5 more
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Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential. [PDF]

PLoS ONE, 2013
It has been recognized that changes in mitochondrial structure plays a key role in development of cardiac dysfunction, and autophagy has been shown to exert maintenance of mitochondrial homeostasis effects.
Li Wang, Keyi Lu, Haihu Hao, Xiaoyu Li, Jie Wang, Ke Wang, Jin Wang, Zi Yan, Suli Zhang, Yunhui Du, Huirong Liu   +10 more
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The relationship of myocardial and liver T2* values with cardiac function and laboratory findings in transfusion-dependent thalassemia major patients: A retrospective cardiac MRI study [PDF]

Journal of Cardiovascular and Thoracic Research, 2023
Introduction: Cardiac complications are the leading cause of death in thalassemia patients. It is assumed that progressive iron accumulation results in myocyte damage. Myocardial T2* measurement by cardiac MRI quantifies iron overload.
Sepideh Abdi, Negar Taheri, Fatemeh Zahedi Haghighi, Mahya Khaki, Homa Najafi, Mohammad Mehdi Hemmati Komasi, Behrooz Hassani   +6 more
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Subclinical cardiac dysfunction in obesity patients is linked to autonomic dysfunction: findings from the CARDIOBESE study

ESC Heart Failure, 2020
Aims Obesity doubles the lifetime risk of developing heart failure. Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient for optimal risk stratification.
Sanne M. Snelder, Lotte E. deGroot‐de Laat, L. Ulas Biter, Manuel Castro Cabezas, Nadine Pouw, Erwin Birnie, Bianca M. Boxma‐de Klerk, René A. Klaassen, Felix Zijlstra, Bas M. vanDalen   +9 more
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Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency. [PDF]

PLoS ONE, 2014
Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better than
Jianmin Chen, Fausto Chiazza, Massimo Collino, Nimesh S A Patel, Sina M Coldewey, Christoph Thiemermann   +5 more
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Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection

Scientific Reports, 2019
Accumulating evidence has confirmed that the expression of sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) is downregulated in heart failure and cardiac allograft rejection.
Estefanía Tarazón, Carolina Gil-Cayuela, María García Manzanares, Marta Roca, Francisca Lago, José Ramón González-Juanatey, Elena Sánchez-Lacuesta, Luis Martínez-Dolz, Manuel Portolés, Esther Roselló-Lletí   +9 more
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Diagnosing Preclinical Cardiac Dysfunction in Swiss Childhood Cancer Survivors: Protocol for a Single-Center Cohort Study

JMIR Research Protocols, 2020
BackgroundCardiovascular disease is the leading nonmalignant cause of late deaths in childhood cancer survivors. Cardiovascular disease and cardiac dysfunction can remain asymptomatic for many years, but eventually lead to progressive disease with high ...
Schindera, Christina, Kuehni, Claudia Elisabeth, Pavlovic, Mladen, Haegler-Laube, Eva Simona, Rhyner, Daniel, Waespe, Nicolas, Roessler, Jochen, Suter, Thomas, von der Weid, Nicolas Xavier   +8 more
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