Results 221 to 230 of about 215,781 (262)

Cardiomyocyte-derived BDNF restricts cardiac fibrosis by decreasing the activity of the TGF-β/Smad2/3 pathway and increasing Smad7 expression. [PDF]

open access: yesFront Cell Dev Biol
Zhu Y   +18 more
europepmc   +1 more source

Septin4 Regulates Cardiac Fibrosis After Pressure Overload. [PDF]

open access: yesCirc Res
Yücel D   +9 more
europepmc   +1 more source

Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis. [PDF]

open access: yesCommun Biol
Wang Z   +17 more
europepmc   +1 more source

Exploring Cardiac Fibrosis

open access: yesJACC: Basic to Translational Science
de Boer, Rudolf A., Ardehali, Reza
openaire   +1 more source

Engineered T cell therapy for the treatment of cardiac fibrosis during chronic phase of myocarditis. [PDF]

open access: yesTheranostics
Hua X   +16 more
europepmc   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai   +4 more
wiley   +1 more source

Integrins in cardiac fibrosis

Journal of Molecular and Cellular Cardiology, 2022
Cells sense mechanical stress and changes in their matrix environment through the integrins, a family of heterodimeric surface receptors that bind to extracellular matrix ligands and trigger cytoskeletal remodeling, while transducing a wide range of intracellular signals.
Ruoshui, Li, Nikolaos G, Frangogiannis
openaire   +4 more sources

Fibrosis and Cardiac Arrhythmias

Journal of Cardiovascular Pharmacology, 2011
In this review article about fibrosis and arrhythmias, we show that the amount of collagen, a normal element of the heart muscle, increases with age and in heart disease. The relation between fibrosis and electrophysiological parameters such as conduction, fractionation of electrograms, abnormal impulse initiation as well as arrhythmogenicity is ...
Sanne, de Jong   +3 more
openaire   +4 more sources

The role of periostin in cardiac fibrosis

Heart Failure Reviews, 2023
Cardiac fibrosis, which is the buildup of proteins in the connective tissues of the heart, can lead to end-stage extracellular matrix (ECM) remodeling and ultimately heart failure. Cardiac remodeling involves changes in gene expression in cardiac cells and ECM, which significantly leads to the morbidity and mortality in heart failure.
Bao Qiao   +3 more
openaire   +2 more sources

Cardiac Fibrosis and Arrhythmogenesis

Comprehensive Physiology, 2017
ABSTRACT Myocardial injury, mechanical stress, neurohormonal activation, inflammation, and/or aging all lead to cardiac remodeling, which is responsible for cardiac dysfunction and arrhythmogenesis. Of the key histological components of cardiac remodeling, fibrosis either in the form of interstitial, patchy, or ...
Nguyen, M, Kiriazis, H, Gao, X, Du, X
openaire   +3 more sources

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