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Application of Hydrogels in Cardiac Regeneration [PDF]

Cardiology and Therapy, 2023
Myocardial infarction (MI) is a leading cause of death globally. Due to limited cardiac regeneration, infarcted myocardial tissue is gradually replaced by cardiac fibrosis, causing cardiac dysfunction, arrhythmia, aneurysm, free wall rupture, and sudden ...
Xuejing Yu
doaj   +2 more sources

The multifaceted nature of endogenous cardiac regeneration [PDF]

Frontiers in Cardiovascular Medicine, 2023
Since the first evidence of cardiac regeneration was observed, almost 50 years ago, more studies have highlighted the endogenous regenerative abilities of several models following cardiac injury.
Laura Rolland, Chris Jopling
doaj   +2 more sources

Melt electrowritten medium chain length polyhydroxyalkanoate cardiac patches for Post-MI cardiac regeneration. [PDF]

Mater Today Bio
Majid QA, Pandey P, Bellahcene M, Grigsby CL, Stevens MM, Talman V, Stuckey DJ, Harding SE, Roy I, Földes G.   +9 more
europepmc   +4 more sources

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration [PDF]

Frontiers in Cardiovascular Medicine
The limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure.
Qingling Xu, Qingling Xu, Xinhui Chen, Chunyige Zhao, Ying Liu, Jianxun Wang, Xiang Ao, Xiang Ao, Wei Ding   +8 more
doaj   +2 more sources

UV-cure hydrogels for cardiac regeneration: a comprehensive review. [PDF]

Stem Cell Res Ther
Pisheh HR, Ghanavati Z, Darvishi A, Seydi M.   +3 more
europepmc   +2 more sources

ENGINEERED EXTRACELLULAR VESICLES AND NANOPARTICLES: PROMISING TOOLS FOR DISEASE TREATMENT [PDF]

Archives of the Balkan Medical Union, 2020
Living forever is a beautiful vision that human being has been pursuing. With the development of science and technology, an increasing number of approaches have been emerging for repairing and regenerating the damaged organs, such as cell therapy, gene ...
Hongyun WANG, Xinyue ZHU, Junjie XIAO
doaj   +1 more source

Direct Cardiac Reprogramming: Progress and Promise. [PDF]

, 2018
The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function after insult; thus, the ability to regenerate and repair the injured myocardium remains a top priority in treating heart failure.
Ardehali, Reza, Engel, James L
core   +17 more sources

Editorial: Cardiac regeneration [PDF]

Frontiers in Cardiovascular Medicine, 2023
Rajika Roy, Claudio de Lucia, Darukeshwara Joladarashi, Ajit Magadum   +3 more
doaj   +2 more sources

Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b

Journal of Sport and Health Science, 2022
Background: Exercise is beneficial for muscle atrophy. Peroxisome proliferator-activated receptor gamma (PPARγ) and microRNA-29b (miR-29b) have been reported to be responsible for angiotensinⅡ (AngⅡ)-induced muscle atrophy. However, it is unclear whether
Qi Liu, Liyang Chen, Xuchun Liang, Yuqing Cao, Xinyue Zhu, Siqi Wang, Jin Li, Juan Gao, Junjie Xiao   +8 more
doaj   +1 more source

Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGFβ/SMAD pathway

Cell Death and Disease, 2022
The activation of pancreatic stellate cells (PSCs) is the key mechanism of pancreatic fibrosis, which can lead to β-cell failure. Oxidative stress is an important risk factor for PSC activation.
Jitai Zhang, Juan Bai, Qian Zhou, Yuxin Hu, Qian Wang, Lanting Yang, Huamin Chen, Hui An, Chuanzan Zhou, Yongyu Wang, Xiufang Chen, Ming Li   +11 more
doaj   +1 more source