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Editorial: Cardiac regeneration [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2023
Rajika Roy   +3 more
doaj   +4 more sources

Application of Hydrogels in Cardiac Regeneration [PDF]

open access: yesCardiology and Therapy, 2023
Myocardial infarction (MI) is a leading cause of death globally. Due to limited cardiac regeneration, infarcted myocardial tissue is gradually replaced by cardiac fibrosis, causing cardiac dysfunction, arrhythmia, aneurysm, free wall rupture, and sudden ...
Xuejing Yu
doaj   +2 more sources

The multifaceted nature of endogenous cardiac regeneration [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2023
Since the first evidence of cardiac regeneration was observed, almost 50 years ago, more studies have highlighted the endogenous regenerative abilities of several models following cardiac injury.
Laura Rolland, Chris Jopling
doaj   +2 more sources

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration [PDF]

open access: yesFrontiers in Cardiovascular Medicine
The limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure.
Qingling Xu   +8 more
doaj   +2 more sources

ENGINEERED EXTRACELLULAR VESICLES AND NANOPARTICLES: PROMISING TOOLS FOR DISEASE TREATMENT [PDF]

open access: yesArchives of the Balkan Medical Union, 2020
Living forever is a beautiful vision that human being has been pursuing. With the development of science and technology, an increasing number of approaches have been emerging for repairing and regenerating the damaged organs, such as cell therapy, gene ...
Hongyun WANG, Xinyue ZHU, Junjie XIAO
doaj   +1 more source

Direct Cardiac Reprogramming: Progress and Promise. [PDF]

open access: yes, 2018
The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function after insult; thus, the ability to regenerate and repair the injured myocardium remains a top priority in treating heart failure.
Ardehali, Reza, Engel, James L
core   +17 more sources

Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b

open access: yesJournal of Sport and Health Science, 2022
Background: Exercise is beneficial for muscle atrophy. Peroxisome proliferator-activated receptor gamma (PPARγ) and microRNA-29b (miR-29b) have been reported to be responsible for angiotensinⅡ (AngⅡ)-induced muscle atrophy. However, it is unclear whether
Qi Liu   +8 more
doaj   +1 more source

Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGFβ/SMAD pathway

open access: yesCell Death and Disease, 2022
The activation of pancreatic stellate cells (PSCs) is the key mechanism of pancreatic fibrosis, which can lead to β-cell failure. Oxidative stress is an important risk factor for PSC activation.
Jitai Zhang   +11 more
doaj   +1 more source

Antithymocyte Globulin Inhibits CD8+ T Cell Effector Functions via the Paracrine Induction of PDL-1 on Monocytes

open access: yesCells, 2023
Background: Antithymocyte globulins (ATG) are T cell-depleting antibodies used in solid organ transplantation for induction therapy in sensitized patients with a high risk of graft rejection.
Dragan Copic   +6 more
doaj   +1 more source

The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring

open access: yesPharmaceutics, 2023
Hypertrophic scars can cause pain, movement restrictions, and reduction in the quality of life. Despite numerous options to treat hypertrophic scarring, efficient therapies are still scarce, and cellular mechanisms are not well understood.
Vera Vorstandlechner   +7 more
doaj   +1 more source

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