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Editorial: Cardiac regeneration [PDF]
Rajika Roy +3 more
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Application of Hydrogels in Cardiac Regeneration [PDF]
Myocardial infarction (MI) is a leading cause of death globally. Due to limited cardiac regeneration, infarcted myocardial tissue is gradually replaced by cardiac fibrosis, causing cardiac dysfunction, arrhythmia, aneurysm, free wall rupture, and sudden ...
Xuejing Yu
doaj +2 more sources
The multifaceted nature of endogenous cardiac regeneration [PDF]
Since the first evidence of cardiac regeneration was observed, almost 50 years ago, more studies have highlighted the endogenous regenerative abilities of several models following cardiac injury.
Laura Rolland, Chris Jopling
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Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration [PDF]
The limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure.
Qingling Xu +8 more
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ENGINEERED EXTRACELLULAR VESICLES AND NANOPARTICLES: PROMISING TOOLS FOR DISEASE TREATMENT [PDF]
Living forever is a beautiful vision that human being has been pursuing. With the development of science and technology, an increasing number of approaches have been emerging for repairing and regenerating the damaged organs, such as cell therapy, gene ...
Hongyun WANG, Xinyue ZHU, Junjie XIAO
doaj +1 more source
Direct Cardiac Reprogramming: Progress and Promise. [PDF]
The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function after insult; thus, the ability to regenerate and repair the injured myocardium remains a top priority in treating heart failure.
Ardehali, Reza, Engel, James L
core +17 more sources
Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b
Background: Exercise is beneficial for muscle atrophy. Peroxisome proliferator-activated receptor gamma (PPARγ) and microRNA-29b (miR-29b) have been reported to be responsible for angiotensinⅡ (AngⅡ)-induced muscle atrophy. However, it is unclear whether
Qi Liu +8 more
doaj +1 more source
The activation of pancreatic stellate cells (PSCs) is the key mechanism of pancreatic fibrosis, which can lead to β-cell failure. Oxidative stress is an important risk factor for PSC activation.
Jitai Zhang +11 more
doaj +1 more source
Background: Antithymocyte globulins (ATG) are T cell-depleting antibodies used in solid organ transplantation for induction therapy in sensitized patients with a high risk of graft rejection.
Dragan Copic +6 more
doaj +1 more source
The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
Hypertrophic scars can cause pain, movement restrictions, and reduction in the quality of life. Despite numerous options to treat hypertrophic scarring, efficient therapies are still scarce, and cellular mechanisms are not well understood.
Vera Vorstandlechner +7 more
doaj +1 more source

