Results 31 to 40 of about 87,451 (296)
Bioactive Compounds and Cardiac Fibrosis: Current Insight and Future Prospect [PDF]
, 2023 Cardiac fibrosis is a pathological condition characterized by excessive deposition of collagen and other extracellular matrix components in the heart. It is recognized as a major contributor to the development and progression of heart failure.
Abdul Majid +4 more
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Cardiac regeneration validated [PDF]
Nature Biotechnology, 2015 Naumova et al. reply: We appreciate the comments from Malliaras and Marban1 describing their work on developing imaging markers of therapeutic efficacy2 that was not mentioned in our review3. Owing to the page limitation, we were not able to cite all the literature published on this topic.
Konstantinos, Malliaras +1 more
openaire +2 more sources
Cardiac regeneration and diabetes [PDF]
Regenerative Medicine Research, 2014 The prevalence of diabetes continues to increase world-wide and is a leading cause of morbidity, mortality, and rapidly rising health care costs. Although strict glucose control combined with good pharmacological and non-pharmacologic interventions can increase diabetic patient life span, the frequency and mortality of myocardial ischemia and ...
Cai Lu, Keller Bradley B
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miRNA in cardiac development and regeneration [PDF]
Cell Regeneration, 2021 AbstractIschemic heart disease is one of the main causes of morbidity and mortality in the world. In adult mammalian hearts, most cardiomyocytes are terminally differentiated and have extremely limited capacity of proliferation, making it impossible to regenerate the heart after injuries such as myocardial infarction. MicroRNAs (miRNAs), a class of non-
Zhaohui Ouyang, Ke Wei
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Recent insights into zebrafish cardiac regeneration. [PDF]
, 2020 In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to cardiac failure, one of the leading causes of death worldwide.
Sanz-Morejon, Andres, Mercader, Nadia
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Cardiac Fibroblasts and Myocardial Regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The billions of cardiomyocytes lost to acute myocardial infarction (MI) cannot be replaced by the limited regenerative capacity of adult mammalian hearts, and despite decades of research, there are still no clinically effective therapies for remuscularizing and restoring damaged myocardial tissue.
Wangping Chen +4 more
openaire +3 more sources
Analysis of Exosome Transfer in Mammalian Cells by Fluorescence Recovery after Photobleaching
Bio-Protocol, 2018 During the course of evolution, prokaryote and eukaryote cells have developed elegant and to some extent analogous strategies to communicate with each other and to adapt to their surrounding environment.
Hernán González-King +9 more
doaj +1 more source
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b
Molecular Therapy: Nucleic Acids, 2021 The activation of the renin-angiotensin system (RAS) induced by increased angiotensin II (AngII) levels has been implicated in muscle atrophy, which is involved in the pathogenesis of congestive heart failure.
Jin Li +12 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2020 Muscle atrophy is a common complication of heart failure. At present, there is no specific treatment to reverse the course of muscle atrophy. Exercise training, due to the safety and easy operation, is a recommended therapy for muscle atrophy induced by ...
Qi Liu +4 more
doaj +1 more source
npj Regenerative Medicine, 2023 Neonatal mouse heart can regenerate after left ventricle (LV) apical resection (AR). Since current AR rodent method is accomplished by resecting LV apex until exposure of LV chamber, it is relatively difficult to operate reproducibly. We aimed to develop
Yihua Bei +12 more
doaj +1 more source