Results 41 to 50 of about 87,451 (296)
Scientific Reports, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the ...
Christine Bekos +12 more
doaj +1 more source
Frontiers in Physiology, 2018 Emerging evidence indicates the beneficial effects of physical exercise on human health, which depends on the intensity, training time, exercise type, environmental factors, and the personal health status.
Yongqin Li +8 more
doaj +1 more source
Reprogramming for cardiac regeneration
Global Cardiology Science and Practice, 2014 Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods
Raynaud, Christophe Michel +5 more
openaire +4 more sources
Direct Reprogramming of Cardiac Fibroblasts to Repair the Injured Heart [PDF]
, 2021 Coronary heart disease is a leading cause of mortality and morbidity. Those that survive acute myocardial infarction are at significant risk of subsequent heart failure due to fibrotic remodelling of the infarcted myocardium.
Rachel McCloy +9 more
core +1 more source
Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433
Frontiers in Genetics, 2019 Cardiac fibrosis is the pathological consequence of fibroblast proliferation and fibroblast-to-myofibroblast transition. As a new class of endogenous non-coding RNAs, circular RNAs (circRNAs) have been identified in many cardiovascular diseases including
Yujiao Zhu +6 more
doaj +1 more source
Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach
npj Systems Biology and Applications, 2017 Cardiology: Heart Failure Medication Reduces Heart Size The new wonder drug in heart failure management, Sacubitril/Valsartan, rejuvenates the heart by preventing its dilation. Using data from myocardial infarction and heart failure samples, we generated
Oriol Iborra-Egea +6 more
doaj +1 more source
Circulation Research, 2004 See related article, pages 911–921 Despite current pharmacological and whole organ transplantation strategies, advanced heart failure remains a common and deadly disease.1 Limited availability of donor organs for use in orthotopic heart transplantation has prompted examination of alternative therapeutic strategies directed toward patients with ...
Daniel J. Garry, Cindy M. Martin
openaire +1 more source
Feasibility of allogeneic stem cells for heart regeneration [PDF]
, 2014 Stem cell therapy for heart disease is currently one of the most exciting ideas in regenerative medicine, and allogeneic mesenchymal stem cells (MSCs) are emerging as a lead candidate for cell-based therapeutics.
Suncion, V.Y +7 more
core +1 more source
A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function
JACC: Basic to Translational Science, 2016 Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment.
Isaac Perea-Gil, MS +10 more
doaj +1 more source
Circular RNAs: Promising Biomarkers for Human Diseases
EBioMedicine, 2018 Circular RNA (circRNA) is a group of endogenous noncoding RNA characterized by a covalently closed cyclic structure lacking poly-adenylated tails. Recent studies have suggested that circRNAs play a crucial role in regulating gene expression by acting as ...
Zhongrong Zhang +2 more
doaj +1 more source