Results 41 to 50 of about 158,981 (293)
Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes [PDF]
, 2003 Background - Further to promoting angiogenesis, cell therapy may be an approach for cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into other lineages. However, the transdifferentiation potential of endothelial
Aicher, A +9 more
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Cardiac Fibroblasts and Myocardial Regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The billions of cardiomyocytes lost to acute myocardial infarction (MI) cannot be replaced by the limited regenerative capacity of adult mammalian hearts, and despite decades of research, there are still no clinically effective therapies for remuscularizing and restoring damaged myocardial tissue.
Wangping Chen +4 more
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Frontiers in Cardiovascular Medicine, 2020 Muscle atrophy is a common complication of heart failure. At present, there is no specific treatment to reverse the course of muscle atrophy. Exercise training, due to the safety and easy operation, is a recommended therapy for muscle atrophy induced by ...
Qi Liu +4 more
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Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]
, 2018 Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
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Cardiac stem cells: A promising treatment option for heart failure. [PDF]
, 2012 Cardiovascular diseases are the most common cause of death in the world. The development of heart failure is mainly due to the loss of cardiomyocytes following myocardial infarction and the absence of endogenous myocardial repair.
Huang, Lan, Zhao, Xiaohui
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Reprogramming for cardiac regeneration
Global Cardiology Science and Practice, 2014 Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods
Raynaud, Christophe Michel +5 more
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Circulation Research, 2004 See related article, pages 911–921 Despite current pharmacological and whole organ transplantation strategies, advanced heart failure remains a common and deadly disease.1 Limited availability of donor organs for use in orthotopic heart transplantation has prompted examination of alternative therapeutic strategies directed toward patients with ...
Daniel J. Garry, Cindy M. Martin
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Scientific Reports, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the ...
Christine Bekos +12 more
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Frontiers in Physiology, 2018 Emerging evidence indicates the beneficial effects of physical exercise on human health, which depends on the intensity, training time, exercise type, environmental factors, and the personal health status.
Yongqin Li +8 more
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Bone marrow-derived cells can acquire cardiac stem cells properties in damaged heart [PDF]
, 2011 Experimental data suggest that cell-based therapies may be useful for cardiac regeneration following ischaemic heart disease. Bone marrow (BM) cells have been reported to contribute to tissue repair after myocardial infarction (MI) by a variety of ...
BARILE, Lucio +13 more
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