Results 21 to 30 of about 1,204,541 (198)
Melt electrowritten medium chain length polyhydroxyalkanoate cardiac patches for Post-MI cardiac regeneration. [PDF]
Mater Today BioHuman pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold promise in averting the development of heart failure with reduced ejection fraction (HFrEF) following myocardial infarction (MI) by potentially regenerating the infarcted myocardium and ...
Majid QA +9 more
europepmc +2 more sources
Comparative Analysis of Heart Regeneration: Searching for the Key to Heal the Heart—Part II: Molecular Mechanisms of Cardiac Regeneration [PDF]
, 2023 Cardiovascular diseases are the leading cause of death worldwide, among which ischemic heart disease is the most representative. Myocardial infarction results from occlusion of a coronary artery, which leads to an insufficient blood supply to the ...
Sheila Caño-Carrillo +9 more
core +1 more source
Recent insights into zebrafish cardiac regeneration. [PDF]
, 2020 In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to cardiac failure, one of the leading causes of death worldwide.
Sanz-Morejon, Andres +3 more
core +3 more sources
Comparative Analysis of Heart Regeneration: Searching for the Key to Heal the Heart—Part I: Experimental Injury Models to Study Cardiac Regeneration [PDF]
, 2023 Cardiovascular diseases are the leading cause of death worldwide, among which, ischemic heart disease is the most prevalent. Myocardial infarction results from occlusion of a coronary artery, which leads to an insufficient blood supply to the myocardium.
Sheila Caño-Carrillo +9 more
core +1 more source
The Ontogeny of Cardiac Regeneration [PDF]
Circulation Research, 2011 ### Transient Regenerative Potential of the Neonatal Mouse Heart Porello et al Science . 2011;331:1078–1080 The regenerative capacity of adult human hearts after infarction seems vestigial at best, perhaps because of the poor proliferative capacity of terminally differentiated cardiomyocytes and desecration of the local environment that would ...
Robert M, Graham, Richard P, Harvey
openaire +2 more sources
Hyaluronan and cardiac regeneration [PDF]
Journal of Biomedical Science, 2014 Hyaluronan (HA) is abundantly expressed in several human tissues and a variety of roles for HA has been highlighted. Particularly relevant for tissue repair, HA is actively produced during tissue injury, as widely evidenced in wound healing investigations.
BONAFÈ, FRANCESCA +5 more
openaire +2 more sources
The Key Lnc (RNA)s in Cardiac and Skeletal Muscle Development, Regeneration, and Disease [PDF]
, 2021 Non-coding RNAs (ncRNAs) play a key role in the regulation of transcriptional and epigenetic activity in mammalian cells. Comprehensive analysis of these ncRNAs has revealed sophisticated gene regulatory mechanisms which finely tune the proper gene ...
Naya, Francisco J. +3 more
core +1 more source
Cardiac regeneration validated [PDF]
Nature Biotechnology, 2015 Naumova et al. reply: We appreciate the comments from Malliaras and Marban1 describing their work on developing imaging markers of therapeutic efficacy2 that was not mentioned in our review3. Owing to the page limitation, we were not able to cite all the literature published on this topic.
Konstantinos, Malliaras +1 more
openaire +2 more sources
Cardiac regeneration and diabetes [PDF]
Regenerative Medicine Research, 2014 The prevalence of diabetes continues to increase world-wide and is a leading cause of morbidity, mortality, and rapidly rising health care costs. Although strict glucose control combined with good pharmacological and non-pharmacologic interventions can increase diabetic patient life span, the frequency and mortality of myocardial ischemia and ...
Cai Lu, Keller Bradley B
openaire +3 more sources
Route 411 to Cardiac Regeneration
JACC: Basic to Translational Science, 2022 [Figure: see text]
Siel Van den Bogaert +1 more
openaire +4 more sources