Results 51 to 60 of about 1,204,541 (198)
The Long and Winding Road to Cardiac Regeneration [PDF]
, 2023 Cardiac regeneration is a critical endeavor in the treatment of heart diseases, aimed at repairing and enhancing the structure and function of damaged myocardium.
Di Meglio F. +9 more
core +2 more sources
Nature Communications, 2021 Endothelial cells play a critical role in the adaptation of tissues to injury and show a remarkable plasticity. Here the authors show, using single cell sequencing, that endothelial cells acquire a transient mesenchymal state associated with metabolic ...
Lukas S. Tombor +23 more
doaj +1 more source
Stimulating endogenous cardiac regeneration [PDF]
, 2015 The healthy adult heart has a low turnover of cardiac myocytes. The renewal capacity, however, is augmented after cardiac injury. Participants in cardiac regeneration include cardiac myocytes themselves, cardiac progenitor cells, and peripheral stem ...
Amanda Finan +5 more
core +1 more source
MicroRNAs in heart and circulation during physical exercise
Journal of Sport and Health Science, 2018 Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of eukaryotic gene expression.
Lijun Wang +3 more
doaj +1 more source
World Journal of Cardiology, 2016 The loss of cardiomyocytes during injury and disease can result in heart failure and sudden death, while the adult heart has a limited capacity for endogenous regeneration and repair. Current stem cell-based regenerative medicine approaches modestly improve cardiomyocyte survival, but offer neglectable cardiomyogenesis.
Kamps, Jan A.A.M., Krenning, Guido
openaire +2 more sources
Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis
Scientific Reports, 2022 Left ventricular (LV) remodeling after myocardial infarction (MI) is promoted by an intense fibrotic response, which could be targeted by the anti-fibrotic drug pirfenidone.
Alberto Aimo +8 more
doaj +1 more source
Nature Communications, 2022 The benefit of regular exercise on the heart has been well documented but the role of RNA m6A modification in exercise-induced cardiac remodelling remains largely unknown.
Lijun Wang +10 more
doaj +1 more source
Antioxidants, 2022 Neutrophil extracellular trap (NET)-formation represents an important defence mechanism for the rapid clearance of infections. However, exaggerated NET formation has been shown to negatively affect tissue-regeneration after injury.
Katharina Klas +10 more
doaj +1 more source
Cardiac Regeneration and Stem Cells [PDF]
Physiological Reviews, 2015 After decades of believing the heart loses the ability to regenerate soon after birth, numerous studies are now reporting that the adult heart may indeed be capable of regeneration, although the magnitude of new cardiac myocyte formation varies greatly.
Yiqiang, Zhang +2 more
openaire +2 more sources
Revascularization of chronic total occlusion coronary artery and cardiac regeneration
Frontiers in Cardiovascular Medicine, 2022 Coronary chronic total occlusion (CTO) contributes to the progression of heart failure in patients with ischemic cardiomyopathy. Randomized controlled trials demonstrated that percutaneous coronary intervention (PCI) for CTO significantly improves angina
Ruoxi Liao +4 more
doaj +1 more source