Results 51 to 60 of about 158,981 (293)

Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433

Frontiers in Genetics, 2019
Cardiac fibrosis is the pathological consequence of fibroblast proliferation and fibroblast-to-myofibroblast transition. As a new class of endogenous non-coding RNAs, circular RNAs (circRNAs) have been identified in many cardiovascular diseases including
Yujiao Zhu, Wen Pan, Tingting Yang, Xiangmin Meng, Zheyi Jiang, Lichan Tao, Lijun Wang   +6 more
doaj   +1 more source

Some International Constitutional Aspects of the Palestine Case [PDF]

, 1968
Cardiac tissue engineering via the use of stem cells is the future for repairing impaired heart function that results from a myocardial infarction.
Gelmi, Amy, Jager, Edwin, Kozak Ljunggren, Monika, Rafat, Mehrdad   +3 more
core   +2 more sources

Noninvasive assessment of an engineered bioactive graft in myocardial infarction: impact on cardiac function and scar healing [PDF]

, 2016
Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in
Bayés Genis, Antoni, Bogónez-Franco, Paco, Bragós Bardia, Ramon, Crisóstomo, Verónica, Díaz Güemes, Idoia, Gálvez Montón, Carolina, Llucia Valldeperes, A., Perea Gil, Isaac, Prat Vidal, Cristina, Roura, Santiago, Soler Botija, Carolina, Sánchez Margallo, Francisco M.   +11 more
core   +10 more sources

Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach

npj Systems Biology and Applications, 2017
Cardiology: Heart Failure Medication Reduces Heart Size The new wonder drug in heart failure management, Sacubitril/Valsartan, rejuvenates the heart by preventing its dilation. Using data from myocardial infarction and heart failure samples, we generated
Oriol Iborra-Egea, Carolina Gálvez-Montón, Santiago Roura, Isaac Perea-Gil, Cristina Prat-Vidal, Carolina Soler-Botija, Antoni Bayes-Genis   +6 more
doaj   +1 more source

Evidence for mechanisms underlying the functional benefits of a myocardial matrix hydrogel for post-MI treatment [PDF]

, 2016
Background There is increasing need for better therapies to prevent the development of heart failure after myocardial infarction (MI). An injectable hydrogel derived from decellularized porcine ventricular myocardium has been shown to halt the post ...
Braden, Rebecca L., Christman, Karen L., Demaria, Anthony N., Gaetani, Roberto, Garcia, Julian J., Huang, Diane, Luo, Colin G., Omens, Jeffrey H., Wassenaar, Jean W.   +8 more
core   +1 more source

A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function

JACC: Basic to Translational Science, 2016
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment.
Isaac Perea-Gil, MS, Cristina Prat-Vidal, PhD, Carolina Gálvez-Montón, DVM, PhD, Santiago Roura, PhD, Aida Llucià-Valldeperas, PhD, Carolina Soler-Botija, PhD, Oriol Iborra-Egea, MS, Idoia Díaz-Güemes, DVM, PhD, Verónica Crisóstomo, DVM, PhD, Francisco M. Sánchez-Margallo, DVM, PhD, Antoni Bayes-Genis, MD, PhD   +10 more
doaj   +1 more source

Lessons learnt in the first year of an Australian pediatric cardio oncology clinic

Cardio-Oncology, 2023
Background Modern oncological therapies together with chemotherapy and radiotherapy have broadened the agents that can cause cardiac sequelae, which can manifest for pediatric oncology patients while on active treatment.
Claudia Toro, Ben Felmingham, Mangesh Jhadav, David S. Celermajer, Andre La Gerche, John O’Sullivan, Sanjeev Kumar, Marion K. Mateos, Joy Fulbright, Dinisha Govender, Lane Collier, Michael Cheung, David D. Eisenstat, Peter W. Lange, Julian Ayer, David A. Elliott, Rachel Conyers   +16 more
doaj   +1 more source

Bone marrow mononuclear cells and acute myocardial infarction [PDF]

, 2012
PMCID: PMC3340546This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Arnous, S, Martin, J, Mathur, A, Mozid, A   +3 more
core   +1 more source

Circular RNAs: Promising Biomarkers for Human Diseases

EBioMedicine, 2018
Circular RNA (circRNA) is a group of endogenous noncoding RNA characterized by a covalently closed cyclic structure lacking poly-adenylated tails. Recent studies have suggested that circRNAs play a crucial role in regulating gene expression by acting as ...
Zhongrong Zhang, Tingting Yang, Junjie Xiao   +2 more
doaj   +1 more source

Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]

, 2020
This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core   +2 more sources