Results 71 to 80 of about 87,451 (296)
Direct Cardiac Reprogramming in the Age of Computational Biology [PDF]
Heart disease continues to be one of the most fatal conditions worldwide. This is in part due to the maladaptive remodeling process by which ischemic cardiac tissue is replaced with a fibrotic scar. Direct cardiac reprogramming presents a unique solution
Jiandong Liu +3 more
core +1 more source
Cardiac Regeneration Using Pluripotent Stem Cells [PDF]
, 2017 Article信州医学雑誌 65(3): 143-152(2017)journal ...
柴, 祐司, 門田, 真
core +1 more source
Cardiac Regeneration and Stem Cells [PDF]
Physiological Reviews, 2015 After decades of believing the heart loses the ability to regenerate soon after birth, numerous studies are now reporting that the adult heart may indeed be capable of regeneration, although the magnitude of new cardiac myocyte formation varies greatly.
Yiqiang, Zhang +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Strategies for Cardiac Regeneration and Repair [PDF]
Science Translational Medicine, 2014 Regenerative medicine strategies that enhance heart repair are being pursued to face the growing heart disease epidemic.
Zhiqiang, Lin, William T, Pu
openaire +2 more sources
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Developmental and Evolutionary Heart Adaptations Through Structure–Function Relationships [PDF]
While the heart works as an efficient pump, it also has a high level of adaptivity by changing its structure to maintain function during healthy and diseased states.
Sandra Rugonyi +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Stimulating endogenous cardiac regeneration [PDF]
, 2015 The healthy adult heart has a low turnover of cardiac myocytes. The renewal capacity, however, is augmented after cardiac injury. Participants in cardiac regeneration include cardiac myocytes themselves, cardiac progenitor cells, and peripheral stem ...
Amanda Finan +5 more
core +1 more source
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish [PDF]
, 2023 The human heart is poorly regenerative and cardiac tumors are extremely rare. Whether the adult zebrafish myocardium is responsive to oncogene overexpression and how this condition affects its intrinsic regenerative capacity remains unknown.
Heidi E. L. Lischer +15 more
core +1 more source