Results 71 to 80 of about 158,981 (293)
Antioxidants, 2022 Neutrophil extracellular trap (NET)-formation represents an important defence mechanism for the rapid clearance of infections. However, exaggerated NET formation has been shown to negatively affect tissue-regeneration after injury.
Katharina Klas +10 more
doaj +1 more source
Getting old through the blood. Circulating molecules in aging and senescence of cardiovascular regenerative cells [PDF]
, 2017 Global aging is a hallmark of our century. The natural multifactorial process resulting in aging involves structural and functional changes, affecting molecules, cells, and tissues.
Angelini, Francesco +5 more
core +2 more sources
Revascularization of chronic total occlusion coronary artery and cardiac regeneration
Frontiers in Cardiovascular Medicine, 2022 Coronary chronic total occlusion (CTO) contributes to the progression of heart failure in patients with ischemic cardiomyopathy. Randomized controlled trials demonstrated that percutaneous coronary intervention (PCI) for CTO significantly improves angina
Ruoxi Liao +4 more
doaj +1 more source
Introductory editorial: drug-eluting stents or drug-eluting grafts? Insights from proteomic analysis [PDF]
, 2017 No abstract ...
Al-Attar, Nawwar +5 more
core +1 more source
Revealing Pathways of Cardiac Regeneration [PDF]
Circulation: Genomic and Precision Medicine, 2018 See Article by Adamowicz, Morgan, and Haubner et al Major cardiac injuries like a large myocardial infarction lead to systolic heart failure because of loss of cardiomyocytes. Unlike during embryonic development,1 adult mammalian cardiomyocytes have limited ability to proliferate and replenish the adult mammalian heart.
Vinícius, Bassaneze, Richard T, Lee
openaire +2 more sources
Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]
, 2019 Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk +5 more
core +1 more source
Cardiac Anisotropy, Regeneration, and Rhythm [PDF]
Circulation Research, 2014 With great interest, we read the commentary of Anderson et al1 on the recent publication of Chong et al2 about the large-scale use of human embryonic stem cell–derived cardiomyocytes to regenerate infarcted, nonhuman primate myocardium. In their commentary, they focus on the development of ventricular tachyarrhythmias after injection of large numbers ...
Pijnappels, D.A. +3 more
openaire +3 more sources
Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells [PDF]
, 2016 Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological behavior of cardiac valve substitutes.
Aguiari, Paola +11 more
core +2 more sources
Mechanisms of Cardiac Repair and Regeneration [PDF]
Circulation Research, 2018 Cardiovascular regenerative therapies are pursued on both basic and translational levels. Although efficacy and value of cell therapy for myocardial regeneration can be debated, there is a consensus that profound deficits in mechanistic understanding limit advances, optimization, and implementation.
Broughton, Kathleen M +6 more
openaire +5 more sources
miR-29b contributes to multiple types of muscle atrophy
Nature Communications, 2017 Skeletal muscle atrophy can occur in response to stimuli such as inactivity, fasting, and ageing. Here the authors show that expression of microRNA-29b promotes muscle atrophy by targeting IGF-1 and PI3K, and that its inhibition attenuates atrophy ...
Jin Li +11 more
doaj +1 more source