Results 91 to 100 of about 1,204,541 (198)

Circular RNAs as Potential Theranostics in the Cardiovascular System

Molecular Therapy: Nucleic Acids, 2018
Cardiovascular diseases (CVDs) represent the largest contributor to mortality worldwide. Identification of novel therapeutic targets and biomarkers for CVDs is urgently needed. Circular RNAs (circRNAs) are endogenous, abundant, and stable non-coding RNAs
Yihua Bei, Tingting Yang, Lijun Wang, Paul Holvoet, Saumya Das, Joost P.G. Sluijter, Marta Chagas Monteiro, Yang Liu, Qiulian Zhou, Junjie Xiao   +9 more
doaj   +1 more source

International Cardiovascular Development, Anatomy, and Regeneration (ICDAR) Community Meeting: Prague 2024

The International Cardiovascular Anatomy, Development, and Regeneration meeting was held from 18–20 September 2024, in Prague, Czech Republic, supported by the European Society of Cardiology’s Working Group on Development, Anatomy, and ...
Maurice van den Hoff, David Sedmera, Antonio Baldini, Bill Chaudhry   +3 more
core   +1 more source

Cardiac muscle regeneration: lessons from development

, 2011
The adult human heart is an ideal target for regenerative intervention since it does not functionally restore itself after injury yet has a modest regenerative capacity that could be enhanced by innovative therapies. Adult cardiac cells with regenerative
Mark Mercola, Michael D. Schneider, Pilar Ruiz-Lozano   +2 more
core   +1 more source

Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering [PDF]

BioImpacts
Introduction: Biomaterials currently utilized for the regeneration of myocardial tissue seem to associate with certain restrictions, including deficiency of electrical conductivity and sufficient mechanical strength.
Nazanin Amiryaghoubi, Marziyeh Fathi
doaj   +1 more source

tsRNA-3025a Impairs Mitochondrial Function and Autophagy to Inhibit Myocardial Regeneration and Repair Following Ischemia–Reperfusion Injury

Myocardial ischemia–reperfusion (I/R) injury is a frequent complication of acute myocardial infarction (AMI), yet clinical biomarkers and targets remain limited.
Yumo Yang, Ai Zhou, Kaixuan Tang, Lingmei Qian, Zehao Feng, Ying Chen, Xing Li, Li Zhang, Han Zhang   +8 more
core   +1 more source

Biomaterials for cardiac regeneration

, 2015
This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart.
Ruel, Marc, Suuronen, Erik
core   +1 more source

Human Cardiac Development and Regeneration Modeling [PDF]

Human cardiac development and regeneration modeling are crucial areas of research that hold immense promise for advancing regenerative medicine and treating cardiovascular diseases.
Mason, Sheila Moffitt
core   +1 more source

Cardiac biomarkers: a focus on cardiac regeneration.

The journal of Tehran Heart Center, 2011
HISTORICALLY, BIOMARKERS HAVE BEEN USED IN TWO MAJOR WAYS TO MAINTAIN AND IMPROVE BETTER HEALTH STATUS: first, for diagnostic purposes, and second, as specific targets to treat various diseases. A new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born.
Reza Forough, Catherine Scarcello, Matthew Perkins   +2 more
openaire   +3 more sources

Hippo pathway effector Yap promotes cardiac regeneration

, 2013
The adult mammalian heart has limited potential for regeneration. Thus, after injury, cardiomyocytes are permanently lost, and contractility is diminished.
Bassel-Duby, Rhonda, Olson, Eric N., Qi, Xiaoxia, Xin, Mei, Kim, Yuri, Sutherland, Lillian B., Shelton, John M., Murakami, Masao, Tan, Wei, Richardson, James A., McAnally, John, Porrello, Enzo R., Sadek, Hesham A., Mahmoud, Ahmed I.   +13 more
core   +1 more source

Developmental and Evolutionary Heart Adaptations Through Structure–Function Relationships

While the heart works as an efficient pump, it also has a high level of adaptivity by changing its structure to maintain function during healthy and diseased states.
Sandra Rugonyi, Marina Nimmo, Makena Phillips   +2 more
core   +1 more source