Results 111 to 120 of about 87,451 (296)

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

The role of bone marrow derived cells in cardiac repair [PDF]

open access: yes, 2012
PhDCurrent pharmacological therapies fail to address the final end-point of cardiac ischaemia — the death and dysfunction of cardiomyocytes. Advances in stem cell biology have provided hope, for the first time, of addressing this underlying pathology.
Lovell, Matthew J, Lovell, Matthew J.
core  

Population-specific genetic differences of acute coronary syndrome in Han and Uyghur Chinese

open access: yesFrontiers in Pharmacology
BackgroundAcute coronary syndrome (ACS) is a critical cardiovascular condition with diverse clinical presentations, necessitating personalized therapeutic approaches.
Hongmei Lai   +18 more
doaj   +1 more source

Circular RNAs as Potential Theranostics in the Cardiovascular System

open access: yesMolecular Therapy: Nucleic Acids, 2018
Cardiovascular diseases (CVDs) represent the largest contributor to mortality worldwide. Identification of novel therapeutic targets and biomarkers for CVDs is urgently needed. Circular RNAs (circRNAs) are endogenous, abundant, and stable non-coding RNAs
Yihua Bei   +9 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

open access: yesAdvanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase   +6 more
wiley   +1 more source

The Functional Significance of Cardiac Looping: Comparative Embryology, Anatomy, and Physiology of the Looped Design of Vertebrate Hearts [PDF]

open access: yes
The flow path of vertebrate hearts has a looped configuration characterized by curved (sigmoid) and twisted (chiral) components. The looped heart design is phylogenetically conserved among vertebrates and is thought to represent a significant determinant
Männer, Jörg, Jörg Männer
core   +1 more source

Stem Cell Therapies for Cardiac Regeneration: Current Burden—Future Directions [PDF]

open access: yes, 2015
Although treatment for acute myocardial infarction has improved over the past decades, including early reperfusion of occluded coronary arteries, novel therapeutic strategies are required to preserve cardiac function and improve clinical outcomes in ...
Rosalinda Madonna
core   +1 more source

Biointegrated Battery‐Based Electroceuticals

open access: yesAdvanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou   +6 more
wiley   +1 more source

Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering [PDF]

open access: yesBioImpacts
Introduction: Biomaterials currently utilized for the regeneration of myocardial tissue seem to associate with certain restrictions, including deficiency of electrical conductivity and sufficient mechanical strength.
Nazanin Amiryaghoubi, Marziyeh Fathi
doaj   +1 more source

Reviewing the Limitations of Adult Mammalian Cardiac Regeneration: Noncoding RNAs as Regulators of Cardiomyogenesis

open access: yesBiomolecules, 2020
The adult mammalian heart is incapable of regeneration following cardiac injury, leading to a decline in function and eventually heart failure. One of the most evident barriers limiting cardiac regeneration is the inability of cardiomyocytes to divide ...
Robin Verjans   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy