Results 101 to 110 of about 87,451 (296)

New Developments in Cardiac Regeneration [PDF]

Heart, Lung and Circulation, 2017
Numerous pharmacological and device therapies have improved adverse cardiac remodelling and mortality in heart failure. However, none are able to regenerate damaged cardiac tissue. Stem cell based therapies using multipotent (adult) stem cells and pluripotent stem cells are new approaches that could potentially achieve the elusive goal of true cardiac ...
Thi Yen Loan, Le, Sujitha, Thavapalachandran, Eddy, Kizana, James Jh, Chong   +3 more
openaire   +2 more sources

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Pathological Structural Alterations of Serous Cell Cilia in the Parietal Pericardium of Patients With Heart Failure Induced by Dilated Cardiomyopathy

Reviews in Cardiovascular Medicine
Background: This study aimed to examine pathological surface structural changes in serous cells of the pericardial parietal layer in patients with heart failure due to dilated cardiomyopathy.
Yingtian Liu, Yaping Xu, Yan Chen, Yuexin Yu, Ziyu Liu, Xiangli Zhang, Bin Yang, Zhikun Guo   +7 more
doaj   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Stem cells and cardiac regeneration [PDF]

Transplant International, 2007
Despite many advances in cardiovascular medicine, heart failure (HF) remains the leading cause of death in developed countries affecting at least 10 million people in Western Europe alone. The poor long-term prognosis of HF patients, and immense public health implications has fuelled interest in finding new therapeutic modalities.
Alfred A, Kocher, Bernhard, Schlechta, Aneta, Gasparovicova, Ernst, Wolner, Nikolaos, Bonaros, Günther, Laufer   +5 more
openaire   +2 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

A single-cell atlas revealing cellular heterogeneity across healthy and diseased human thymus

Nature Communications
The human thymus plays a key role in the development of the adaptive immune system. Its development and pathologic aberrations with missing involution occupy the scientific world for years.
Martin Direder, Matthias Wielscher, Melanie Salek, Maria Laggner, Dragan Copic, Katharina Klas, Daniel Bormann, Bahar Golabi, Hannes Kühtreiber, Marie-Therese Lingitz, Leonhard Müllauer, Ana-Iris Schiefer, Wolfgang Weninger, Clemens Aigner, Hendrik Jan Ankersmit, Michael Mildner, Bernhard Moser   +16 more
doaj   +1 more source

Targeting Mettl14 Using an RNA‐Targeting Clustered Regularly Interspaced Short Palindromic Repeat‐High‐Fidelity Cas13x System Attenuates Doxorubicin‐Induced Cardiotoxicity

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Doxorubicin is an effective chemotherapy drug used to treat various types of cancer. However, doxorubicin treatment is associated with cardiotoxicity, which limits its clinical use.
Wensi Wan, Caiyue Cui, Yi Zhou, Jiaqi Wang, Xuan Zhao, Xinxin Cui, Jiangpeng Sun, Pujiao Yu, Jingyi Feng, Tianhui Wang, Lijun Wang, Jiahong Xu   +11 more
doaj   +1 more source

POSS‐PEG‐NHS and GSH Cocrosslink DPAV to Prepare Anticalcification Bioprosthetic Scaffold With Enhanced Reendothelization, Anti‐inflammation, and Anti‐ROS

Advanced Healthcare Materials, EarlyView.
POSS‐PEG‐NHS and GSH cocrosslinked DPAV to prepare a multifunctional anticalcification valve substitute. This modification enhances mechanical properties, hemocompatibility, and re‐endothelialization while promoting anti‐inflammatory M2 macrophage infiltration and reducing calcification.
Yuqing Zhang, Chen Qian, Yingjie He, Jingli Ding, Binhao Zhang, Minghui Zou, Xing Chen, Jinping Zhao, Cuifen Lu, Jinping Liu, Jianliang Zhou   +10 more
wiley   +1 more source

Cardiac muscle regeneration [PDF]

, 1982
This study analyzed the regenerative ability of cardiac muscle in the rat. Normal cardiac muscle from the rat was minced into one mm 3 fragments and homotransplanted into a gastrocnemius cavity of a non-sibling rat.
Metzger, Joseph M.
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