Results 1 to 10 of about 1,102,092 (211)

Overcoming the roadblocks to cardiac cell therapy using tissue engineering [PDF]

, 2017
Transplantations of various stem cells or their progeny have repeatedly improved cardiac performance in animal models of myocardial injury; however, the benefits observed in clinical trials have been generally less consistent.
Bolli, Roberto, Bursac, Nenad, Dorn, Gerald W, Garry, Daniel J, Hare, Joshua M, Jun, Ho-wook, Kamp, Timothy J, Kitsis, Richard N, Prabhu, Sumanth D, Yanamandala, Mounica, Yoon, Young-sup, Zhang, Jianyi, Zhu, Wuqiang   +12 more
core   +4 more sources

Ventricular stabilization with a customized decellularized cardiac ECM-based scaffold after myocardial infarction alters gene expression in a rodent LAD-ligation model

Frontiers in Bioengineering and Biotechnology, 2022
Objectives: Decellularized extracellular matrix (dECM) is increasingly used in a wide range of regenerative medicine applications and may also offer the potential to support injured myocardium.
Hug Aubin, Hug Aubin, Lenard Rath, Alexandra Vey, Vera Schmidt, Vera Schmidt, Mareike Barth, Mareike Barth, Elvira Weber, Elvira Weber, Artur Lichtenberg, Artur Lichtenberg, Payam Akhyari, Payam Akhyari   +13 more
doaj   +1 more source

BEaTS-β: an open-source electromechanical bioreactor for simulating human cardiac disease conditions

Frontiers in Bioengineering and Biotechnology, 2023
Heart disease remains the leading cause of worldwide mortality. Although the last decades have broadened our understanding of the biology behind the pathologies of heart disease, ex vivo systems capable of mimicking disease progression and abnormal heart
Hiroki Takaya, Maxime Comtois-Bona, Maxime Comtois-Bona, Ana Spasojevic, David Cortes, David Cortes, Fabio Variola, Wenbin Liang, Wenbin Liang, Marc Ruel, Erik J. Suuronen, Erik J. Suuronen, Emilio I. Alarcon, Emilio I. Alarcon   +13 more
doaj   +1 more source

Diet Rich in Lard Promotes a Metabolic Environment Favorable to Trypanosoma cruzi Growth

Frontiers in Cardiovascular Medicine, 2021
Background:Trypanosoma cruzi is a protozoan parasite that causes Chagas disease and affects 6–7 million people mainly in Latin America and worldwide.
Débora Maria Soares de Souza, Débora Maria Soares de Souza, Débora Maria Soares de Souza, Maria Cláudia Silva, Silvia Elvira Barros Farias, Ana Paula de J. Menezes, Cristiane Maria Milanezi, Karine de P. Lúcio, Nívia Carolina N. Paiva, Paula Melo de Abreu, Daniela Caldeira Costa, Daniela Caldeira Costa, Kelerson Mauro de Castro Pinto, Kelerson Mauro de Castro Pinto, Guilherme de Paula Costa, Guilherme de Paula Costa, João Santana Silva, João Santana Silva, André Talvani, André Talvani, André Talvani   +20 more
doaj   +1 more source

AIBP Regulates Metabolism of Ketone and Lipids but Not Mitochondrial Respiration

Cells, 2022
Accumulating evidence indicates that the APOA1 binding protein (AIBP)—a secreted protein—plays a profound role in lipid metabolism. Interestingly, AIBP also functions as an NAD(P)H-hydrate epimerase to catalyze the interconversion of NAD(P)H hydrate [NAD(
Jun-dae Kim, Teng Zhou, Aijun Zhang, Shumin Li, Anisha A. Gupte, Dale J. Hamilton, Longhou Fang   +6 more
doaj   +1 more source

Detection of Abnormal Cardiac Response Patterns in Cardiac Tissue Using Deep Learning

Mathematics, 2022
This study reports a method for the detection of mechanical signaling anomalies in cardiac tissue through the use of deep learning and the design of two anomaly detectors.
Xavier Marimon, Sara Traserra, Marcel Jiménez, Andrés Ospina, Raúl Benítez   +4 more
doaj   +1 more source

The effect of eight weeks high intensity interval training on the expression of cardiac miRNA-21 and miRNA-1 in wistar male rats [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2022
Background and Purpose: microRNA (miRNA) are a new class of biomarkers that are involved in many biological processes and gene expression. Also, High-intensity exercise training (HIIT) has long been demonstrated to help improve cardiorespiratory fitness ...
Sohrab Ghalehgir, Javad Vakili, Mostafa Khani, Karim Azali Alamdari   +3 more
doaj   +1 more source

3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography

eLife, 2021
For the first time, we have used phase-contrast X-ray tomography to characterize the three-dimensional (3d) structure of cardiac tissue from patients who succumbed to Covid-19. By extending conventional histopathological examination by a third dimension,
Marius Reichardt, Patrick Moller Jensen, Vedrana Andersen Dahl, Anders Bjorholm Dahl, Maximilian Ackermann, Harshit Shah, Florian Länger, Christopher Werlein, Mark P Kuehnel, Danny Jonigk, Tim Salditt   +10 more
doaj   +1 more source

Endurance Training Regulates Expression of Some Angiogenesis-Related Genes in Cardiac Tissue of Experimentally Induced Diabetic Rats

Biomolecules, 2021
Exercise can ameliorate cardiovascular dysfunctions in the diabetes condition, but its precise molecular mechanisms have not been entirely understood.
Mojdeh Khajehlandi, Lotfali Bolboli, Marefat Siahkuhian, Mohammad Rami, Mohammadreza Tabandeh, Kayvan Khoramipour, Katsuhiko Suzuki   +6 more
doaj   +1 more source

The Curie effect incorporation in the monodomain equation describing the action potential dynamics in cardiac tissue [PDF]

INCAS Bulletin, 2023
In their in-depth study on cardiac tissue modeling, Clayton and Panfilov [1] present several monodomain or bidomain approaches for the mathematical description of the cardiac tissue action potential dynamics.
Agneta M. BALINT, Stefan BALINT, Adrian NECULAE   +2 more
doaj   +1 more source