Results 111 to 120 of about 86,066 (247)

Cardiac Tissue Bioprinting: Integrating Structure and Functions Through Biomimetic Design, Bioinks, and Stimulation

Gels
Pathologies of the heart (e.g., ischemic disease, valve fibrosis and calcification, progressive myocardial fibrosis, heart failure, and arrhythmogenic disorders) stem from the irreversible deterioration of cardiac tissues, leading to severe clinical ...
Silvia Marino, Reem Alheijailan, Rita Alonaizan, Stefano Gabetti, Diana Massai, Maurizio Pesce   +5 more
doaj   +1 more source

Cardiac tissue engineering for the treatment of hypoplastic left heart syndrome (HLHS). [PDF]

Transl Pediatr, 2023
Abraham R, Vricella L, Hibino N.
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

How to fix a broken heart-designing biofunctional cues for effective, environmentally-friendly cardiac tissue engineering. [PDF]

Front Chem, 2023
Benko A, Webster TJ.
europepmc   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

Engineering cardiac tissue: The role of topographic cues in cardiomyocytes

Journal of Applied Biomaterials & Functional Materials
Cardiovascular diseases represent a leading cause of mortality on a global scale. Engineered cardiac tissue applied as in vitro model have great potential on discovering myocardium pathology mechanisms and developing new drugs.
Maoyu Qin, Xinyi Chen, Ping Zhu
doaj   +1 more source

Emerging technologies for cardiac tissue engineering and artificial hearts. [PDF]

Smart Med, 2023
Sun L, Wang Y, Xu D, Zhao Y.
europepmc   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source

Mechanical properties of the rabbit and human decellularized patches for well-tolerated/reinforced organ in cardiac tissue engineering. [PDF]

J Cardiovasc Thorac Res, 2023
Mousavi Khatat M, Same S, Moharamzadeh K, Soleimani Rad J, Mehdipour A, Roshangar L.   +5 more
europepmc   +1 more source