Results 11 to 20 of about 86,066 (247)
Cardiac tissue engineering [PDF]
We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (~108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport ...
MILICA RADISIC, GORDANA VUNJAK-NOVAKOVIC
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Nanomaterials for Cardiac Tissue Engineering [PDF]
End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients.
Devang R. Amin +5 more
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Electrospun Acellular Heart ECM for Cardiac Tissue Engineering [PDF]
Electrospun nanofiber is one of the promising alternatives for use in tissue engineering and drug delivery due to its controllable characteristics. However, choosing an appropriate biomaterial for a specific tissue regeneration plays a significant role ...
Sh. mashayekhiyan +5 more
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Recapitulating Cardiac Structure and Function In Vitro from Simple to Complex Engineering
Cardiac tissue engineering aims to generate in vivo-like functional tissue for the study of cardiac development, homeostasis, and regeneration.
Ana Rita M. P. Santos +4 more
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Engineered cardiac tissues [PDF]
Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor ...
Rohin K, Iyer +3 more
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Cardiac Tissue Engineering [PDF]
The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
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Cardiac Tissue Engineering [PDF]
The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for the past decade. Profound advances in human stem cell biology and technology, tissue engineering and material sciences, as well as prevascularization and in vitro assay technologies make the first clinical application of engineered cardiac tissues a realistic option
George Eng +3 more
+5 more sources
Engineering virtual cardiac tissue [PDF]
The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
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Cardiac Organoids to Model and Heal Heart Failure and Cardiomyopathies
Cardiac tissue engineering aims at creating contractile structures that can optimally reproduce the features of human cardiac tissue. These constructs are becoming valuable tools to model some of the cardiac functions, to set preclinical platforms for ...
Magali Seguret +3 more
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Engineered Human Cardiac Tissue [PDF]
The human heart is the first organ to develop during embryogenesis and is arguably the most essential organ for life. However, after birth, the heart has very little capacity to repair malformations such as congenital heart defects or to regenerate after an injury such as myocardial infarction.
Kareen L, Kreutziger, Charles E, Murry
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