Results 41 to 50 of about 648 (69)

Manufacturing a Biomimetic Biorecator in Cardiac Tissue Engineering

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: The direct approach of cardiac tissue engineering is to mimic the natural tissue of heart, considering the significant role of scaffolding and mechanical simulation.
Zahra Shams   +3 more
doaj  

Engineered Macroscale Cardiac Constructs Elicit Human Myocardial Tissue-like Functionality

open access: yesStem Cell Reports, 2019
Summary: In vitro surrogate models of human cardiac tissue hold great promise in disease modeling, cardiotoxicity testing, and future applications in regenerative medicine.
Maria Valls-Margarit   +13 more
doaj   +1 more source

Engineering a robust and anisotropic cardiac-specific extracellular matrix scaffold for cardiac patch tissue engineering

open access: yesMatrix Biology Plus
Extracellular matrix (ECM) fabricated using human induced pluripotent stem cells (hiPSCs)-derived cardiac fibroblasts (hiPSC-CFs) could serve as a completely biological scaffold for an engineered cardiac patch, leveraging the unlimited source and ...
Te-An Chen   +7 more
doaj   +1 more source

Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trialResearch in context

open access: yesEBioMedicine
Summary: Background: In preclinical studies, the use of double allogeneic grafts has shown promising results in promoting tissue revascularization, reducing infarct size, preventing adverse remodelling and fibrosis, and ultimately enhancing cardiac ...
Antoni Bayes-Genis   +16 more
doaj   +1 more source

Investigating the utilization of biomaterials and bioengineering methods in developing functional cardiac tissue for heart repair

open access: yesMGM Journal of Medical Sciences
It has become increasingly apparent that cardiac tissue engineering applications can be employed to repair heart injuries. The primary purpose of the present research is to examine the use of biomaterials and bioengineering methods to create functioning ...
Omar Elsaka
doaj   +1 more source

Cardiac Tissue Bioprinting: Integrating Structure and Functions Through Biomimetic Design, Bioinks, and Stimulation

open access: yesGels
Pathologies of the heart (e.g., ischemic disease, valve fibrosis and calcification, progressive myocardial fibrosis, heart failure, and arrhythmogenic disorders) stem from the irreversible deterioration of cardiac tissues, leading to severe clinical ...
Silvia Marino   +5 more
doaj   +1 more source

Organ-on-a-Chip and Lab-on-a-Chip Technologies in Cardiac Tissue Engineering

open access: yesBiomimetics
Microfluidic technologies have ushered in a new era in cardiac tissue engineering, providing more predictive in vitro models compared to two-dimensional culture studies. This review examines Organ-on-a-Chip (OoC) and Lab-on-a-Chip (LoC) platforms, with a
Daniele Marazzi   +3 more
doaj   +1 more source

Engineering cardiac tissue: The role of topographic cues in cardiomyocytes

open access: yesJournal of Applied Biomaterials & Functional Materials
Cardiovascular diseases represent a leading cause of mortality on a global scale. Engineered cardiac tissue applied as in vitro model have great potential on discovering myocardium pathology mechanisms and developing new drugs.
Maoyu Qin, Xinyi Chen, Ping Zhu
doaj   +1 more source

Cardiac tissue engineering and regeneration using cell-based therapy

open access: yesStem Cells and Cloning: Advances and Applications, 2015
Mohammad T Alrefai,1–3 Divya Murali,4 Arghya Paul,4 Khalid M Ridwan,1,2 John M Connell,1,2 Dominique Shum-Tim1,2 1Division of Cardiac Surgery, 2Division of Surgical Research, McGill University Health Center, Montreal, QC, Canada; 3King Faisal ...
Alrefai MT   +5 more
doaj  

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