Results 1 to 10 of about 53,047 (204)
Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid. [PDF]
PLoS ONE, 2013 Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway.
Olivier Jalmar +10 more
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Cardiolipin’s multifaceted role in immune response: a focus on interacting proteins [PDF]
Frontiers in ImmunologyCardiolipin is a unique and essential phospholipid that plays a pivotal role in cellular function. In eukaryotic cells, it is predominantly localized within the mitochondrial membranes, with the highest concentration in the inner mitochondrial membrane ...
Zhuodong Chai +9 more
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Ionization constants pKa of cardiolipin. [PDF]
PLoS ONE, 2013 Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
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Selective remodeling of cardiolipin fatty acids in the aged rat heart [PDF]
Lipids in Health and Disease, 2006 Background The heart is rich in cardiolipin, a phospholipid acylated in four sites, predominately with linoleic acid. Whether or not aging alters the composition of cardiolipin acyl chains is controversial.
Rapoport Stanley I +3 more
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Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry. [PDF]
PLoS ONE, 2013 Cardiolipin, a major component of mitochondria, is critical for mitochondrial functioning including the regulation of cytochrome c release during apoptosis and proper electron transport.
Yuan-Hao Hsu +3 more
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Redox Biology, 2023 Cardiolipin is a unique phospholipid of the inner mitochondrial membrane (IMM) as well as in bacteria. It performs several vital functions such as resisting osmotic rupture and stabilizing the supramolecular structure of large membrane proteins, like ATP
Sehwan Jang, Sabzali Javadov
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Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling. [PDF]
PLoS ONE, 2014 Cell survival from the arrested state can be a cause of the cancer recurrence. Transition from the arrest state to the growth state is highly regulated by mitochondrial activity, which is related to the lipid compositions of the mitochondrial membrane ...
Yu-Jen Chao +4 more
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Ischemia In Vivo Induces Cardiolipin Oxidation in Rat Kidney Mitochondria
Biology, 2022 Cardiolipin is a mitochondrial phospholipid that plays a significant role in mitochondrial bioenergetics. Cardiolipin is oxidized under conditions like oxidative stress that occurs during ischemia/reperfusion; however, it is known that even during ...
Arvydas Strazdauskas +5 more
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PLoS ONE, 2022 Cardiolipin is known to interact with bacterial and mitochondrial proteins and protein complexes. Unlike in Escherichia coli and Saccharomyces cerevisiae, the synthesis of cardiolipin is essential for growth of Trypanosoma brucei parasites in culture ...
Alessio Loffreda +2 more
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Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
Biology, 2022 Cardiolipin is a specific phospholipid of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production.
Alexandre Prola, Fanny Pilot-Storck
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