Results 91 to 100 of about 36,754 (231)
Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa
The FEBS Journal, EarlyView.Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley +1 more source
Antigenicity of bacterial membrane-cardiolipin and reactivity of anti-cardiolipin antibody with bacteria and DNA [PDF]
, 1988 I investigated the possibility of production of antibody to bacterial membrane-cardiolipin using cardiolipin micelles, Staphylococcus aureus (S.aureus) and L-form of S. aureus. I also investigated and the reactivity of anti-cardiolipin (CL) antibody with
Nakamura, Tomoaki, Tomoaki NAKAMURA
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The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
, 2023 Most antimicrobial peptides (AMPs) exert their microbicidal activity through membrane permeabilization. The designed AMP EcDBS1R4 has a cryptic mechanism of action involving the membrane hyperpolarization of Escherichia coli, suggesting that EcDBS1R4 may
López Montero, Iván +6 more
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Diminished exercise capacity and mitochondrial bc1 complex deficiency in tafazzin-knockdown mice.
Frontiers in Physiology, 2013 The phospholipid, cardiolipin, is essential for maintaining mitochondrial structure and optimal function. Cardiolipin-deficiency in humans, Barth syndrome, is characterized by exercise intolerance, dilated cardiomyopathy, neutropenia and 3-methyl ...
Corey ePowers +3 more
doaj +1 more source
The FEBS Journal, EarlyView.Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva +5 more
wiley +1 more source
PTPMT1: Connecting Cardiolipin Biosynthesis to Mitochondrial Function
, 2011 Cardiolipin, a phospholipid component of the inner mitochondrial membrane, is required for mitochondrial metabolism. In this issue, Zhang et al. (2011) highlight a critical role for PTPMT1, a mitochondrial phosphatase, in cardiolipin biogenesis and ...
Tremblay, Michel L. +3 more
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Abstract 067 | Special lecture: cardiolipin and mitochondrial quality control in aging
European Journal of Translational MyologyA progressive decline in mitochondrial oxidative phosphorylation (OxPhos) is a fundamental feature of aging and a strong predictor of mobility loss, cognitive decline, and dementia.
Luigi Ferrucci
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Isolation and purification of cardiolipin from beef heart.
Journal of Lipid Research, 1985 A simple and efficient procedure is described for the preparation of cardiolipin sodium salt from beef heart. A crude phospholipid fraction is isolated by chloroform-methanol extraction of the homogenized tissue, followed by acetone precipitation and ...
E B Smaal +4 more
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Lupus anticoagulant (LA) testing is essential, albeit complex, in the laboratory diagnosis of antiphospholipid syndrome (APS). Given the multi‐step workflow and the variability introduced by anticoagulant therapy, reagent differences, and interpretive approaches, result interpretation requires expert evaluation.
Chiara Novelli +4 more
wiley +1 more source