Results 81 to 90 of about 36,754 (231)

A comprehensive review of cancer‐induced cardiac wasting

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena   +5 more
wiley   +1 more source

Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure

open access: yesJournal of Lipid Research, 2007
The mitochondrial phospholipid cardiolipin is required for optimal mitochondrial respiration. In this study, cardiolipin molecular species and cytochrome oxidase (COx) activity were studied in interfibrillar (IF) and subsarcolemmal (SSL) cardiac ...
Genevieve C. Sparagna   +8 more
doaj   +1 more source

Phase Behavior Of Cardiolipin [PDF]

open access: yes, 2012
Cardiolipin is a phospholipid with negatively charged headgroups. This lipid is structurally unique in its quadruple-chained configuration and functionally unique in its nearly exclusive involvement in the cellular energy production processes.
Chen, Yi-fan
core  

Lipid Coating Modulates Effects of Nanoceria on Oxidative Metabolism in Human Embryonic Lung Fibroblasts: A Case of Cardiolipin

open access: yesBiomolecules
The unique redox properties of nanoscale cerium dioxide determine its diverse application in biology and medicine as a regulator of oxidative metabolism. Lipid modifiers of the nanoparticle surface change their biochemical properties and bioavailability.
Elena V. Proskurnina   +9 more
doaj   +1 more source

Selective remodeling of cardiolipin fatty acids in the aged rat heart

open access: yesLipids in Health and Disease, 2006
Background The heart is rich in cardiolipin, a phospholipid acylated in four sites, predominately with linoleic acid. Whether or not aging alters the composition of cardiolipin acyl chains is controversial.
Rapoport Stanley I   +3 more
doaj   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

open access: yesThe FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump   +10 more
wiley   +1 more source

Untersuchung der immunstimulatorischen Eigenschaften des Phospholipids Cardiolipin

open access: yes, 2017
Die Zielsetzung dieser Arbeit war die Untersuchung der immunstimulatorischen Fähigkeiten des Phospholipids Cardiolipin. Cardiolipin erfüllt die Kriterien eines Pathogen-assoziierten-molekularen-Musters (pathogen-associated molecular pattern; PAMP). Zudem
Bauer, Stefan (Prof. Dr.)   +1 more
core   +1 more source

Highly Canalized MinD Transfer and MinE Sequestration Explain the Origin of Robust MinCDE-Protein Dynamics [PDF]

open access: yes, 2012
Min-protein oscillations in Escherichia coli are characterized by the remarkable robustness with which spatial patterns dynamically adapt to variations of cell geometry.
Frey, Erwin   +3 more
core   +1 more source

Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients

open access: yesItalian Journal of Medicine
Cardiolipin, a critical phospholipid involved in mitochondrial function, has a potential role in the pathogenesis of type 2 diabetes mellitus.
Ayesha Aslam   +7 more
doaj   +1 more source

Novel preparation of cardiolipin from beef heart

open access: yesJournal of Lipid Research, 1970
A new method is described for the isolation of beef heart cardiolipin. A lipid-protein complex, rich in cardiolipin, is obtained by a one-step solvent fractionation of the tissue total lipid extract. Cardiolipin in the complex is largely freed of protein
Joseph Eichberg, John D. Burnham
doaj   +1 more source

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