Results 11 to 20 of about 57,535 (289)
Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid. [PDF]
PLoS ONE, 2013 Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway.
Olivier Jalmar +10 more
doaj +17 more sources
Ionization constants pKa of cardiolipin. [PDF]
PLoS ONE, 2013 Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
doaj +4 more sources
Ischemia In Vivo Induces Cardiolipin Oxidation in Rat Kidney Mitochondria
Biology, 2022 Cardiolipin is a mitochondrial phospholipid that plays a significant role in mitochondrial bioenergetics. Cardiolipin is oxidized under conditions like oxidative stress that occurs during ischemia/reperfusion; however, it is known that even during ...
Arvydas Strazdauskas +5 more
doaj +1 more source
PLoS ONE, 2022 Cardiolipin is known to interact with bacterial and mitochondrial proteins and protein complexes. Unlike in Escherichia coli and Saccharomyces cerevisiae, the synthesis of cardiolipin is essential for growth of Trypanosoma brucei parasites in culture ...
Alessio Loffreda +2 more
doaj +1 more source
Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
Biology, 2022 Cardiolipin is a specific phospholipid of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production.
Alexandre Prola, Fanny Pilot-Storck
doaj +1 more source
Measuring cardiolipin antibodies [PDF]
BMJ, 1995 EDITOR,—Cardiolipin antibodies have been variously cited as a risk factor for cerebral thrombosis1 2 or splanchnic venous thrombosis,3 or as an epiphenomenon loosely associated with vascular disease.4 Cardiolipin antibodies seem to represent a family of low affinity antibodies which share a limited ability to bind to bovine cardiolipin.
A M, Ward, P A, White
openaire +2 more sources
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
TRPM8 Regulates Mitochondrial Ca2+-Dynamics, Temperature and Endoplasmic Reticulum-Mitochondrial Contact Points in T Cell. [PDF]
J Cell Mol MedABSTRACT TRPM8 is a cold temperature‐sensitive and non‐selective Ca2+‐channel. Previously we have observed that TRPM8 is endogenously expressed and affects T cell activation process. Now, we report that TRPM8 regulates functions of mitochondria and ER, two important sub‐cellular compartments.
Acharya TK +5 more
europepmc +2 more sources
Frontiers in Molecular Biosciences, 2021 Cardiolipin is a tetra-acylated di-phosphatidylglycerol lipid enriched in the matrix-facing (inner) leaflet of the mitochondrial inner membrane. Cardiolipin plays an important role in regulating mitochondria function and dynamics.
Yifan Ge +9 more
doaj +1 more source
Journal of Lipid Research, 2008 In this article, the formation of prokaryotic and eukaryotic cardiolipin is reviewed in light of its biological function. I begin with a detailed account of the structure of cardiolipin, its stereochemistry, and the resulting physical properties, and I ...
Michael Schlame
doaj +1 more source