Results 91 to 100 of about 3,383 (226)

Overlooked components of lipid metabolism: Odd‐chain polyunsaturated fatty acids in photosynthetic microorganisms

Journal of Phycology, EarlyView.
Abstract This mini‐review examines odd‐carbon polyunsaturated fatty acids (odd‐PUFAs), a rare but biologically significant group of fatty acids in photosynthetic microorganisms. Odd‐PUFAs are straight‐chain fatty acids containing an odd number of carbon atoms and two or more methylene‐interrupted double bonds. They typically account for less than 1% of
Linda Nedbalová, Milada Vítová, Tomáš Řezanka   +2 more
wiley   +1 more source

Revisiting the action spectrum of DNA damage: Chemiexcitation and the expanded biological spectrum of cyclobutane pyrimidine dimer formation

Photochemistry and Photobiology, EarlyView.
UVB and UVA generate cyclobutane pyrimidine dimers (CPDs) during irradiation (purple). After exposure ends, chemiexcitation in pigmented melanocytes continues to generate delayed CPDs (yellow), even as repair removes some pre‐existing lesions. Consequently, total CPD burden can rise while visible erythema fades.
Jyoti Srivastava, Marcus S. Cooke, Sanjay Premi   +2 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Mapping syphilis surveillance: Insights into blood donation screening practices worldwide

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Syphilis is caused by the bacterial spirochete Treponema pallidum and can be transmitted through blood transfusion. However, there have been less than 10 documented transfusion‐transmitted cases since World War II.
Michel‐Andrés García‐Otálora, Guillermo Orjuela‐Falla, Carl P. McDonald, Sandra Ramirez‐Arcos, ISBT Transfusion‐Transmitted Infectious Diseases Working Party Subgroup on Bacteria   +4 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen, Che‐Lun Chin, Qingzhen Zhu, Ling Chao, Kaori Sugihara   +4 more
wiley   +2 more sources

Influence of diet-induced obesity and voluntary exercise training on cardiac lipids and mitochondrial function in mice

Journal of Sport and Health Science
Background: Obesity is a risk factor for developing cardiometabolic disease. Exercise training is pivotal in the treatment of obesity and is associated with reduced cardiovascular mortality.
Nimna Perera, Minh Deo, Surafel Tegegne, Yow Keat Tham, Natalie A. Mellett, Anida Velagic, Alex M. Parker, Oliver K. Fuller, Lauren V. Terry, Casey L. Egan, Peter J. Meikle, Rebecca H. Ritchie, Mark A. Febbraio, Miles J. De Blasio   +13 more
doaj   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Untargeted lipidomics is commonly performed at analytical flow rates, which consume more solvent and may require higher on‐column sample loads when sensitivity is limited by analyte abundance. Nano flow separations use lower flow rates and sample loads, reducing solvent consumption and facilitating improved electrospray ionization ...
Ciara J. Sallowicz, Thiago Mattos, Rahul R. Deshpande, Bashar Amer, Susan S. Bird   +4 more
wiley   +1 more source