Results 91 to 100 of about 3,234 (169)
Protein Science, Volume 35, Issue 6, June 2026.Abstract Mitochondrial cristae architecture is central for optimal oxidative phosphorylation and a healthy mitochondrial physiology. The intricate architecture of the inner mitochondrial membrane relies on protein complexes that compartmentalize the membrane by imposing membrane curvature, forming membrane contact sites or membrane subdomains ...
Patrick Horten +3 more
wiley +1 more source
Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller +6 more
wiley +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.Oral administration of Lactobacillus paracasei L9 (L9) reshapes the gut microbiota, specifically increasing the abundance of short‐chain fatty acid (SCFA)‐producing bacteria (e.g., Blautia), thereby leading to a significant elevation of serum propionic acid (97% increase) and butyric acid (193% increase).
Ran Bi +10 more
wiley +1 more source
A Structural Context for the Mechanisms of Uncoupling Protein 1 in Brown Fat Thermogenesis
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Uncoupling Protein 1 (UCP1) is a defining feature of brown fat and facilitates the specialized ability of the tissue to generate heat in the process of non‐shivering thermogenesis. The protein is activated by fatty acids, which overcome its inhibition by purine nucleotides, to catalyze proton leak across the mitochondrial inner membrane ...
Riccardo Cavalieri +7 more
wiley +1 more source
Педиатрическая фармакология, 2006 Thrombophilia in children with diffuse connective tissue disorders as systemic lupus erythematosus (SLE) and juvenile dermatomyositis (JDM) could arise from various causes including peripherial blood circulation of antiphospholipid antibodies (APH) and ...
O.A. Solntseva
doaj +2 more sources
British Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source
Chemical Biology &Drug Design, Volume 107, Issue 6, June 2026.SS‐31 (Elamipretide) inhibits α‐synuclein aggregation on the membranes and emerges as a promising therapeutic candidate against mitochondrial dysfunction in Parkinson's disease. ABSTRACT Membrane binding and aggregation properties of α‐synuclein are closely associated with Parkinson's disease and a class of related syndromes named as synucleinopathy ...
Ewelina Stefaniak +5 more
wiley +1 more source
International Journal of Cosmetic Science, Volume 48, Issue 3, Page 500-517, June 2026.Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley +1 more source
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
Immunology, Volume 178, Issue 2, Page 218-230, June 2026.This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Colorectal cancer is a prevalent malignancy, with colon adenocarcinoma (COAD) representing its most common histological subtype. Although most stage I patients remain disease‐free after treatment, a subset rapidly progresses to advanced disease with markedly reduced survival.
Danni Zhao +8 more
wiley +1 more source