Results 71 to 80 of about 4,774 (217)
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2019 In the original publication of this article [1], the images of Figs. 4 and 5 were exchanged and the legends of the two figures did not correspond due to a typesetting error.
Mineko Terao +15 more
doaj +1 more source
Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy
Frontiers in Neuroscience, 2019 Mitochondrial quality control is important in neurological diseases, but in genetic Parkinson’s disease caused by mutations in PINK and parkin mitochondrial degradation through autophagy is crucial. Reductions in autophagy and mitophagy are implicated in
Angel Gaudioso +4 more
doaj +1 more source
Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness [PDF]
, 2016 Gulf War Illness (GWI) affects 25% of veterans from the 1990–1991 Gulf War (GW) and is accompanied by damage to the brain regions involved in memory processing. After twenty-five years, the chronic pathobiology of GWI is still unexplained.
Abdullah, Laila +15 more
core +1 more source
The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases
Exploration, EarlyView.This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li +3 more
wiley +1 more source
Frontiers in Dentistry, 2009 Objective: Evidence shows periodontally infected patients may be at a higher risk of thrombotic accidents and adverse pregnancy outcomes, via induced systemic inflammatory mediators' production.
SH. Faghihi +2 more
doaj
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. [PDF]
, 2019 Gasdermin E (GSDME/DFNA5) cleavage by caspase-3 liberates the GSDME-N domain, which mediates pyroptosis by forming pores in the plasma membrane.
Alnemri, Emad S. +5 more
core +3 more sources
Cardiolipins and biomembrane function [PDF]
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1992 Evidence is discussed for roles of cardiolipins in oxidative phosphorylation mechanisms that regulate State 4 respiration by returning ejected protons across and over bacterial and mitochondrial membrane phospholipids, and that regulate State 3 respiration through the relative contributions of proteins that transport protons, electrons and/or ...
openaire +3 more sources
Rhenium Complexes as Antimicrobial Agents
Helvetica Chimica Acta, EarlyView.Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley +1 more source
Redox Biology, 2014 Emerging evidence indicates that mitochondrial cardiolipins (CL) are prone to free radical oxidation and this process appears to be intimately associated with multiple biological functions of mitochondria.
Huiqin Zhong +4 more
doaj +1 more source