Results 51 to 60 of about 85,199 (269)

Foxk1 and Foxk2 promote cardiomyocyte proliferation and heart regeneration

open access: yesNature Communications
Promoting endogenous cardiomyocyte proliferation is a promising strategy for cardiac repair. Identifying key factors that regulate cardiomyocyte proliferation can advance the development of novel therapies for heart regeneration.
Dongcheng Cai   +15 more
doaj   +1 more source

Cardiomyocyte Renewal in Humans [PDF]

open access: yesCirculation Research, 2012
Pas de ...
Bergmann, Olaf   +5 more
openaire   +4 more sources

3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications

open access: yesFrontiers in Cardiovascular Medicine, 2019
Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Christian Zuppinger
doaj   +1 more source

Extrusion‐Based Additive Manufacturing of Advanced Ceramics: Strengthening Mechanisms and Process Optimization Review

open access: yesAdvanced Engineering Materials, EarlyView.
This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari   +4 more
wiley   +1 more source

Apoptosis of Cardiomyocytes in Myocarditis

open access: yesFolia Biologica, 2006
Apoptosis of cardiomyocytes has been reported to be involved in the pathogenesis of heart failure of different aetiologies. The purpose of this study is to assess the role and extent of apoptosis of cardiomyocytes in active myocarditis. Endomyocardial samples from the right ventricle of 22 patients with active myocarditis were compared with 25 traffic ...
R, Zorc-Pleskovic   +5 more
openaire   +2 more sources

How to make a cardiomyocyte [PDF]

open access: yesDevelopment, 2014
During development, cardiogenesis is orchestrated by a family of heart progenitors that build distinct regions of the heart. Each region contains diverse cell types that assemble to form the complex structures of the individual cardiac compartments.
Daniela, Später   +3 more
openaire   +2 more sources

Cardiomyocyte‐Specific Snrk Prevents Inflammation in the Heart

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The SNRK (sucrose‐nonfermenting–related kinase) enzyme is critical for cardiac function. However, the underlying cause for heart failure observed in Snrk cardiac conditional knockout mouse is unknown.
Karthikeyan Thirugnanam   +15 more
doaj   +1 more source

Mettl14 Attenuates Cardiac Ischemia/Reperfusion Injury by Regulating Wnt1/β-Catenin Signaling Pathway

open access: yesFrontiers in Cell and Developmental Biology, 2021
N6-methyladenosine (m6A) methylation in RNA is a dynamic and reversible modification regulated by methyltransferases and demethylases, which has been reported to participate in many pathological processes of various diseases, including cardiac disorders.
Ping Pang   +21 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Periplocymarin Plays an Efficacious Cardiotonic Role via Promoting Calcium Influx

open access: yesFrontiers in Pharmacology, 2020
Periplocymarin, which belongs to cardiac glycosides, is an effective component extracted from Periplocae Cortex. However, its cardiovascular effects remain unidentified. In the present study, injection of periplocymarin (5 mg/kg) through external jugular
Weijing Yun   +5 more
doaj   +1 more source

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