Results 101 to 110 of about 234,827 (207)
Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes [PDF]
, 2017 Thioredoxin 1 (Trx1) is a 12-kDa oxidoreductase that catalyzes thiol-disulfide exchange reactions to reduce proteins with disulfide bonds. As such, Trx1 helps protect the heart against stresses, such as ischemia and pressure overload.
Bhat, Santosh +16 more
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Molecular Communications For Cardiomyocytes
39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2017 The continued miniaturization of electronics makes it realistic to monitor internal cardiac disease processes by wireless implantable medical sensors and actuators incorporated in implantable cardiac devices. In order to deal with some cardiac diseases, this paper introduces the molecular communication methods for cardiac muscle cell communications.
Lu, Pengfei +3 more
openaire +2 more sources
Divergent Effects of Resveratrol on Rat Cardiac Fibroblasts and Cardiomyocytes
Molecules, 2019 In this study, we tested the potential cardioprotective effects of the phytoalexin resveratrol (Rsv) on primary adult rat cardiac fibroblasts (CF), myofibroblasts (MF) and cardiomyocytes.
Xavier Lieben Louis +9 more
doaj +1 more source
Mesenchymal stem cells as the near future of cardiology medicine - truth or wish?
Biomedical Papers, 2019 Cardiac damage is one of major cause of worldwide morbidity and mortality. Despite the development in pharmacotherapy, cardiosurgery and interventional cardiology, many patients remain at increased risk of developing adverse cardiac remodeling.
Michaela Brychtova +5 more
doaj +1 more source
Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure
Frontiers in Physiology, 2018 Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction ...
Gabriele G. Schiattarella +16 more
doaj +1 more source
Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]
, 2008 An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Erin Lane +7 more
core +1 more source
Pregnancy-associated cardiac dysfunction and the regulatory role of microRNAs. [PDF]
, 2020 Many crucial cardiovascular adaptations occur in the body during pregnancy to ensure successful gestation. Maladaptation of the cardiovascular system during pregnancy can lead to complications that promote cardiac dysfunction and may lead to heart ...
Aryan, Laila +3 more
core
New England Journal of Medicine, 2009 Michael S, Parmacek, Jonathan A, Epstein
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Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes
Frontiers in Physiology, 2013 Apart from ATP synthesis mitochondria have many other functions, one being nitrite reductase activity. NO released from nitrite has been shown to protect the heart from ischemia/reperfusion injury in a cGMP-dependent manner.
Peter eDungel +5 more
doaj +1 more source
Cytokines and Cardiomyocyte Death
Annals of Medicine, 1997 Cytokines have been associated with the pathogenesis of acute coronary syndromes and chronic heart failure (CHF), which are both associated with cardiomyocyte loss. In CHF, increased serum concentrations of proinflammatory cytokines, including tumour necrosis factor alpha (TNF-alpha) and also soluble TNF receptor have been found.
openaire +2 more sources