Results 81 to 90 of about 234,827 (207)
Frontiers in Bioengineering and Biotechnology, 2020 Cardiovascular diseases represent the major cause of morbidity and mortality worldwide. Multiple studies have been conducted so far in order to develop treatments able to prevent the progression of these pathologies.
Marta Mazzola +2 more
doaj +1 more source
eLife, 2022 Ryanodine receptors (RyRs) exhibit dynamic arrangements in cardiomyocytes, and we previously showed that ‘dispersion’ of RyR clusters disrupts Ca2+ homeostasis during heart failure (HF) (Kolstad et al., eLife, 2018).
Xin Shen +14 more
doaj +1 more source
Highly efficient transfection of human induced pluripotent stem cells using magnetic nanoparticles. [PDF]
, 2018 PurposeThe delivery of transgenes into human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hiPSC-CMs) represents an important tool in cardiac regeneration with potential for clinical applications.
Chavez, Karen S +11 more
core +2 more sources
MetabolitesBackground/Objectives: Stimulation of glucose uptake in response to ischemic stress is important for cardiomyocyte post-ischemic function and survival. In the diabetic myocardium chronically exposed to an excess of circulating lipids, this mechanism is ...
Ettore Vanni, Christophe Montessuit
doaj +1 more source
Experimental review of cobalt induced cardiomyopathy
Russian Open Medical Journal, 2017 The heart is a target of injury for many chemical compounds, both medically prescribed and not. Pathophysiological mechanisms underlying development of chemical-induced cardiomyopathies vary depending on the inciting agent, and can include: direct toxic ...
Igor V. Zadnipryany +3 more
doaj +1 more source
Advanced NanoBiomed Research, 2022 Rebuilding damaged or diseased tissue by means of biological additive manufacturing has recently gained lot of attention and shown very promising result. Using biofabrication techniques to mimic and replicate natural tissue as well as cell environment is
Fabian Züger +3 more
doaj +1 more source
Connexin 40 promoter-based enrichment of embryonic stem cell-derived cardiovascular progenitor cells [PDF]
, 2008 Background: Pluripotent embryonic stem (ES) cells that can differentiate into functional cardiomyocytes as well as vascular cells in cell culture may open the door to cardiovascular cell transplantation.
David, R. +2 more
core +1 more source
Mechanobiology of cardiomyocyte development [PDF]
Journal of Biomechanics, 2010 Cardiac cells are under constant, self-generated mechanical stress which can affect the differentiation of stem cells into cardiac myocytes, the development of differentiated cells and the maturation of cells in neonatal mammals. In this article, the effects of direct stretch, electrically induced beating and substrate elasticity on the behavior and ...
Jeffrey G, Jacot +2 more
openaire +2 more sources
Cardiac Muscle Cell‐Based Coupled Oscillator Network for Collective Computing
Advanced Intelligent Systems, 2021 Current rate of data generation and the need for real‐time data analytics can benefit from new computational approaches where computation proceeds in a massively parallel way while being scalable and energy efficient.
Xiang Ren +8 more
doaj +1 more source
Inhibition of histone deacetylase as a treatment for cardiac hypertrophy [PDF]
, 2005 The present invention provides for methods of treating and preventing cardiac hypertrophy. Class II HDACs, which are known to participate in regulation of chromatin structure and gene expression, have been shown to have beneficial effects on cardiac ...
Bristow, Michael R. +3 more
core +1 more source