Results 71 to 80 of about 234,827 (207)

Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway

Frontiers in Immunology
IntroductionMyocarditis is an inflammatory injury to the myocardium characterized by disrupted intercellular communication, involving macrophages and cardiomyocytes as key players.
Yanjie Jiang, Yanjie Jiang, Yanjie Jiang, Yingnan You, Yaxue Xie, Yaxue Xie, Shan Zhou, Mengjie Ma, Bo Han, Bo Han   +9 more
doaj   +1 more source

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes

Frontiers in Cell and Developmental Biology, 2017
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CM) represent a potential unlimited cell supply for cardiac tissue engineering and possibly regenerative medicine applications.
Xuetao Sun, Sara S. Nunes, Sara S. Nunes, Sara S. Nunes   +3 more
doaj   +1 more source

Human cardiomyocyte calcium handling and transverse tubules in mid-stage of post-myocardial-infarction heart failure [PDF]

, 2018
Aims: Cellular processes in the heart rely mainly on studies from experimental animal models or explanted hearts from patients with terminal end-stage heart failure (HF).
Condorelli, Gianluigi, Contu, Riccardo, Ellingsen, Øyvind, Haaverstad, Rune, Høydal, Morten Andre, Karevold, Asbjørn, Kemi, Ole J., Kirkeby-Garstad, Idar, Smith, Godfrey L., Stølen, Tomas L., Wahba, Alexander, Wiseth, Rune, Wisløff, Ulrik   +12 more
core   +2 more sources

Sgk1-Dependent Stimulation of Cardiac Na+/H+ Exchanger Nhe1 by Dexamethasone

Cellular Physiology and Biochemistry, 2013
Background/Aims: The serum- and glucocorticoid-inducible kinase Sgk1 contributes to cardiac remodeling and development of heart failure, which is paralelled by Sgk1-dependent stimulation of the cardiac Na+/H+ exchanger Nhe1.
Jakob Voelkl, Venkanna Pasham, Mohamed Siyabeldin E. Ahmed, Britta Walker, Kalina Szteyn, Dietmar Kuhl, Bernhard Metzler, Ioana Alesutan, Florian Lang   +8 more
doaj   +1 more source

Bone marrow mononuclear cells and acute myocardial infarction [PDF]

, 2012
PMCID: PMC3340546This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Arnous, S, Martin, J, Mathur, A, Mozid, A   +3 more
core   +1 more source

Cardiomyocyte Renewal in Humans [PDF]

Circulation Research, 2012
Pas de ...
Bergmann, Olaf, Zdunek, Sofia, Frisén, Jonas, Bernard, Samuel, Druid, Henrik, Jovinge, Stefan   +5 more
openaire   +4 more sources

MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype

Frontiers in Bioengineering and Biotechnology, 2020
Modulation of microRNA expression holds the promise to achieve direct reprogramming of fibroblasts into cardiomyocyte-like cells as a new strategy for myocardial regeneration after ischemic heart disease.
C. Paoletti, C. Divieto, G. Tarricone, F. Di Meglio, D. Nurzynska, V. Chiono   +5 more
doaj   +1 more source

Direct Cardiac Actions of the Sodium Glucose Co‐Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure‐Overload Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We determined if the sodium glucose co‐transporter 2 inhibitor empagliflozin attenuates pressure overload‐induced heart failure in non‐diabetic mellitus mice by direct cardiac effects and the mechanisms involved. Methods and Results Male C57BL/
Xuan Li, Qingguo Lu, Yunguang Qiu, Jussara M. do Carmo, Zhen Wang, Alexandre A. da Silva, Alan Mouton, Ana C. M. Omoto, Michael E. Hall, Ji Li, John E. Hall   +10 more
doaj   +1 more source

Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]

, 2017
The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core   +1 more source

How to make a cardiomyocyte [PDF]

Development, 2014
During development, cardiogenesis is orchestrated by a family of heart progenitors that build distinct regions of the heart. Each region contains diverse cell types that assemble to form the complex structures of the individual cardiac compartments.
Daniela, Später, Emil M, Hansson, Lior, Zangi, Kenneth R, Chien   +3 more
openaire   +2 more sources