Results 21 to 30 of about 3,273,209 (295)

The hypotensive effect of salt substitutes in stage 2 hypertension:a systematic review and meta-analysis [PDF]

open access: yes, 2020
Background: Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subjects with HTN.
Clark, Cain C T   +4 more
core   +2 more sources

Therapeutic Effect of Echium amoenum on Isoproterenol-Induced Heart Failure in Male Rat [PDF]

open access: yesResearch Journal of Pharmacognosy
Background and objectives: Echium amoenum has shown anti-inflammatory and antioxidants properties and is suggested for heart disease in Persian medicine. Methods: To evaluate its cardioprotective effects, 50 male Wistar rats were divided into five groups:
Hossein Jafari   +6 more
doaj   +1 more source

Pharmacological properties of amrinone, a cardiotonic agent

open access: diamondJapanese Journal of Pharmacology, 1984
Mitsugu Hachisu   +4 more
openaire   +2 more sources

Precision medicine considerations for the management of heart disease and stroke in East Asians

open access: yesCardiology Plus, 2020
Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by ...
Candida L Goodnough, Eric R Gross
doaj   +1 more source

"Oxygen sensing" by Na,K-ATPase: These miraculous thiols [PDF]

open access: yes, 2016
Control over the Na,K-ATPase function plays a central role in adaptation of the organisms to hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its "oxygen-sensitivity" is mediated by a variety of redox-sensitive ...
Bogdanova, Anna   +2 more
core   +2 more sources

Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect
Azar Hosseini   +3 more
doaj   +1 more source

Calcium sensitizers: What have we learned over the last 25years? [PDF]

open access: yes, 2018
K
Papp, Gy. Julius   +2 more
core   +1 more source

Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress

open access: yesClinics, 2009
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no study has specifically investigated
Adriano Meneghini   +6 more
doaj   +1 more source

Toad Venom Antiproliferative Activities on Metastatic Melanoma: Bio-Guided Fractionation and Screening of the Compounds of Two Different Venoms

open access: yesBiology, 2020
Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy   +8 more
doaj   +1 more source

New cardiotonic agents

open access: yesSeminars in Anesthesia, Perioperative Medicine and Pain, 1996
D RUGS THAT INCREASE the positive inotropic (ie, cardiotonic) potential of the myocardium are used in a variety of clinical settings. All catecholamines exert their inotropic effects by stimulating adrenergic mediated receptors in the sympathetic nervous system.
Roberta Hines, Stephen Harris
openaire   +1 more source

Home - About - Disclaimer - Privacy