Results 21 to 30 of about 3,273,209 (295)
The hypotensive effect of salt substitutes in stage 2 hypertension:a systematic review and meta-analysis [PDF]
Background: Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subjects with HTN.
Clark, Cain C T +4 more
core +2 more sources
Therapeutic Effect of Echium amoenum on Isoproterenol-Induced Heart Failure in Male Rat [PDF]
Background and objectives: Echium amoenum has shown anti-inflammatory and antioxidants properties and is suggested for heart disease in Persian medicine. Methods: To evaluate its cardioprotective effects, 50 male Wistar rats were divided into five groups:
Hossein Jafari +6 more
doaj +1 more source
Pharmacological properties of amrinone, a cardiotonic agent
Mitsugu Hachisu +4 more
openaire +2 more sources
Precision medicine considerations for the management of heart disease and stroke in East Asians
Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by ...
Candida L Goodnough, Eric R Gross
doaj +1 more source
"Oxygen sensing" by Na,K-ATPase: These miraculous thiols [PDF]
Control over the Na,K-ATPase function plays a central role in adaptation of the organisms to hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its "oxygen-sensitivity" is mediated by a variety of redox-sensitive ...
Bogdanova, Anna +2 more
core +2 more sources
Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria [PDF]
Objective(s): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect
Azar Hosseini +3 more
doaj +1 more source
Calcium sensitizers: What have we learned over the last 25years? [PDF]
K
Papp, Gy. Julius +2 more
core +1 more source
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no study has specifically investigated
Adriano Meneghini +6 more
doaj +1 more source
Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy +8 more
doaj +1 more source
D RUGS THAT INCREASE the positive inotropic (ie, cardiotonic) potential of the myocardium are used in a variety of clinical settings. All catecholamines exert their inotropic effects by stimulating adrenergic mediated receptors in the sympathetic nervous system.
Roberta Hines, Stephen Harris
openaire +1 more source

