British Journal of Pharmacology, EarlyView.Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer +5 more
wiley +1 more source
Charting the Current Landscape and Future Prospects of Cancer Therapy-Related Cardiovascular Toxicity in Cancer Survivors: From Bench to Bedside. [PDF]
Drug Des Devel TherTao S, Yu L, Zhang L, Li J, Wu J, Tan Y.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia +6 more
wiley +1 more source
Integrating network toxicology, machine learning, and molecular dynamics simulations to reveal tanshinone iia's dual mechanisms in TNBC and doxorubicin-induced cardiotoxicity. [PDF]
Sci RepWu B +10 more
europepmc +1 more source
Incidence and Predictors of Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients at a Tertiary Academic Hospital in Indonesia: A Retrospective Cohort Study. [PDF]
Hosp PharmFitrianti AE +6 more
europepmc +1 more source
An update on the landscape of collagen bioactive fragments
The FEBS Journal, EarlyView.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Malnutrition, cachexia and sarcopenia as susceptibility factors for cardiovascular complications in patients with cancer. [PDF]
Front PharmacolPapasotiriou I +3 more
europepmc +1 more source
Journal of Advanced Nursing, EarlyView.ABSTRACT Aim To examine the role of nurses in providing post‐treatment follow‐up care to breast cancer survivors, and to assess the impact of this care on survivors' satisfaction. Methods Scoping review. Data Sources An electronic literature search from PubMed and CINAHL databases was conducted, covering the period from 2013 to November 2023.
Judith Gálvez‐Sánchez +4 more
wiley +1 more source
Anthracyclines and the Heart: A Double-edged Sword With Therapeutic Hopes. [PDF]
J Saudi Heart AssocAlotaibi TM +6 more
europepmc +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Adverse drug event (ADE) reports submitted by veterinary professionals are essential for monitoring the safety and efficacy of marketed veterinary products. Despite this, the majority of veterinary ADEs are not reported. Further education on the topic of pharmacovigilance has been widely explored in human healthcare as a potential facilitator ...
Heather Grieve +4 more
wiley +1 more source