Results 131 to 140 of about 97,116 (340)
Cardiotoxicity risk factors with immune checkpoint inhibitors [PDF]
, 2022 Zachary Brumberger +5 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko +9 more
wiley +1 more source
Cancer Therapy-Induced Cardiotoxicity—A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy [PDF]
, 2021 Anurag Choksey, Kerstin N. Timm
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon +13 more
wiley +1 more source
Comparision of doxorubicin-induced cardiotoxicity in the ICR mice of different sources
Laboratory Animal Research, 2017 Doxorubicin is a widely used chemotherapeutic agents and is now part of standard therapeutic regimens for a variety of cancers (eg, hematopoietic malignancies and advanced solid tumors of the breast, ovary, thyroid, and bone).
Sou Hyun Kim +8 more
doaj +1 more source
Cancer Nexus, EarlyView.ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song +3 more
wiley +1 more source
Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment
Cancer Management and Research, 2022 Matthew Anaka, Omar Abdel-Rahman Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, CanadaCorrespondence: Omar Abdel-RahmanDepartment of Oncology, Cross Cancer Institute, University of Alberta, 11560 University Avenue ...
Anaka M, Abdel-Rahman O
doaj
ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri +12 more
wiley +1 more source
Cell Communication and SignalingAnthracycline antitumor drug doxorubicin (DOX) induces severe cardiotoxicity. Deubiquitinating enzymes (DUBs) are crucial for protein stability and function and play a significant role in cardiac pathophysiology.
Xiaowen Shi +10 more
doaj +1 more source