Results 141 to 150 of about 227,343 (293)
Background: One of the major causes of mortality in patients with kidney failure requiring dialysis is cardiovascular diseases. Metabolic syndrome refers to a collection of metabolic disorders that causes systemic inflammation and therefore plays an ...
Mojgan Mortazavi +4 more
doaj
Cardiovascular-kidney-metabolic syndrome: the interdisciplinary approach. A review
The revealed interrelationships between obesity, type 2 diabetes mellitus, cardiovascular diseases and chronic kidney disease are an important problem of modern healthcare worldwide, which is gradually becoming an epidemic. The study of these diseases in such a combination becomes the subject of discussion among scientists and the topic of various ...
openaire +1 more source
Progress of metabolomics‐centric multi‐omics research in medicine
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang +6 more
wiley +1 more source
Comparison of Blood Pressure and Blood Glucose Level Among Elderly with Non-communicable Disease [PDF]
Due to increasing age, elderly are prone to non-communicable diseases (NCD), such as hypertension (HT) and diabetes mellitus (DM). Easy physical condition monitoring of people with HT and/or DM is by measuring their blood pressure (BP) and/or blood ...
Artsanthia, J. (Jintana) +1 more
core
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Background Cardiovascular-Kidney-Metabolic (CKM) syndrome highlights the interconnections between cardiovascular disease (CVD), chronic kidney disease (CKD), and type 2 diabetes (DM).
Hongcai Wang +4 more
doaj +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source

