Results 121 to 130 of about 3,242,366 (329)

Metabolic syndrome and kidney dysfunction: emerging molecular and cellular mechanisms at the metabolic–renal interface

Frontiers in Endocrinology
Metabolic syndrome and chronic kidney disease frequently coexist, acting synergistically to amplify the risk of adverse cardiovascular and renal outcomes.
William R. Marshall, William R. Marshall, Darren Green, Darren Green, Smeeta Sinha, Smeeta Sinha, Philip A. Kalra, Philip A. Kalra   +7 more
doaj   +1 more source

COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad, Emily Waskow, Hari Tunuguntla, Joseph Spinner, Hanna J. Tadros, Lisa T. Emrick, Daniel G. Calame, Fernando Scaglia   +7 more
wiley   +1 more source

Impact of cardiovascular-kidney-metabolic syndrome staging on clinical outcomes and management of acute pulmonary embolism: A comprehensive analysis. [PDF]

Pulmonary embolism (PE) is a life-threatening condition with high morbidity and mortality rates. Cardiovascular-Kidney-Metabolic (CKM) syndrome, representing a complex interplay of cardiovascular disease, kidney dysfunction, and metabolic disorders, may ...
Barel, Maguli S, Abu-Fanne, Rami, Gatuz, Marlon V, Roguin, Ariel, Folman, Adam, Abramov, Dmitry, Cherevatsky, Shay Zvi, Mamas, Mamas A, Kobo, Ofer   +8 more
core   +1 more source

Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]

, 2010
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M., ZEIHER AM, Saula de Kreutzenberg, Ozaki Takenori, MARUYAMA S, Schmidt-Lucke, Caroline, Andreas M. Zeiher, Takenori Ozaki, Schmidt-Lucke Caroline, Avogaro, Angelo, WERNER N., Meigs, James, Nikos Werner, Meigs James, SCHMIDT LUCKE C, VIGILI DE KREUTZENBERG, SAULA, Shoichi Maruyama, Werner, Nikos, Fadini, Gian Paolo, Nickenig, Georg, OZAKI T, Taguchi Akihiko, DIMMELER S, Caroline Schmidt-Lucke, Werner Nikos, Taguchi, Akihiko, Andreas M Zeiher, MEIGS J, NICKENIG G, Maruyama Shoichi, Angelo Avogaro, Ozaki, Takenori, Gian Paolo Fadini, Fadini Gian Paolo, TAGUCHI A, Dimmeler Stefanie, Stefanie Dimmeler, Dimmeler, Stefanie, De Kreutzenberg, Saula, Maruyama, Shoichi, Akihiko Taguchi, Zeiher, Andreas M., James Meigs, Nickenig Georg, Avogaro Angelo, Georg Nickenig, de Kreutzenberg Saula   +46 more
core   +2 more sources

Pathophysiology and emerging biomarkers of cardiovascular-renal-hepato-metabolic syndrome

Frontiers in Cardiovascular Medicine
Cardiovascular-Renal-Hepatic-Metabolic (CRHM) syndrome characterizes a complex, interrelated disease framework that encompasses cardiovascular disease, chronic kidney disease (CKD), metabolic dysfunction-associated steatotic liver disease, and metabolic ...
John Nzobokela, Lweendo Muchaili, Lweendo Muchaili, Alick Mwambungu, Sepiso K. Masenga, Sepiso K. Masenga, Sepiso K. Masenga, Sepiso K. Masenga, Annet Kirabo, Annet Kirabo, Annet Kirabo, Annet Kirabo, Annet Kirabo   +12 more
doaj   +1 more source

Cardiovascular-Kidney-Metabolic Syndrome in China

JACC: Asia
[Figure: see text]
openaire   +2 more sources

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

The Metabolic Syndrome and Risk of Chronic Kidney Disease: Pathophysiology and Intervention Strategies

Journal of Nutrition and Metabolism, 2012
Metabolic syndrome is characterized by a clustering of cardiovascular risk factors, including abdominal obesity, elevated blood pressure and glucose concentrations, and dyslipidemia.
Heather A. LaGuardia, L. Lee Hamm, Jing Chen   +2 more
doaj   +1 more source

Prevalence and Mortality Association of Different Stages of Cardiovascular-Kidney-Metabolic Syndrome

JACC: Advances
Background The cardiovascular-kidney-metabolic (CKM) syndrome, introduced by the American Heart Association, underscores the interplay among metabolic, renal, and cardiovascular dysfunctions.
Yong-Ming Chen, Xiaoying Wu, Tianxin Long, Yuxiao Jiang, Miao Wang, Z. Lv, Huiming Hou, Ziang Li, Ming Liu   +8 more
semanticscholar   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source