Results 121 to 130 of about 227,343 (293)
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
PharmaceuticalsIntroduction and Objectives: There is limited evidence on the role of glucagon-like peptide-1 receptor agonists in the interplay between cardiovascular disease, chronic kidney disease, and metabolic dysfunction. This work analyzed the efficacy and safety
Alicia Trenas-Calero +8 more
doaj +1 more source
Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases: Role of Adipokines
Cardiology Research and Practice, 2011 Obesity is a chronic disease, whose incidence is alarmingly growing. It is associated with metabolic abnormalities and cardiovascular complications.
Manfredi Tesauro +6 more
doaj +1 more source
Global Burden of the Key Components of Cardiovascular-Kidney-Metabolic Syndrome
Journal of the American Society of NephrologyKey Points Ischemic heart disease and stroke were the leading contributors to the cardiovascular-kidney-metabolic (CKM) syndrome–related burden in 2021.Regions with a middle sociodemographic index, such as Southeast Asia and the Western Pacific, faced the highest burden.The burden of CKM ...
Zhaomin Xie +7 more
openaire +3 more sources
ESC Heart Failure, Volume 12, Issue 2, Page 1295-1303, April 2025.Abstract Background Obesity is a known risk factor for cardiovascular disease (CVD), yet an ‘obesity paradox’ has been observed in various CVD contexts. The impact of obesity on heart failure (HF) patients treated with a wearable cardioverter‐defibrillator (WCD) remains underexplored.
Mohammad Abumayyaleh +18 more
wiley +1 more source
Animal Models for Studying Developmental Origins of Cardiovascular–Kidney–Metabolic Syndrome
BiomedicinesCardiovascular–kidney–metabolic syndrome (CKMS) has become a significant global health challenge. Since CKMS often originates early in life, as outlined by the developmental origins of health and disease (DOHaD) concept, prevention is a more effective strategy than treatment.
You-Lin Tain +2 more
openaire +3 more sources
ESC Heart Failure, Volume 12, Issue 2, Page 1336-1345, April 2025.Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García +17 more
wiley +1 more source
Prognosis of non-albuminuric patients with the cardiovascular–kidney–metabolic syndrome
Clinical Kidney JournalABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome affects a significant portion of the general population. Urinary albumin-to-creatinine ratio (UACR) is an important indicator of kidney injury.
Xiao Bi +8 more
openaire +2 more sources
Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
Epilepsia, EarlyView.Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon +9 more
wiley +1 more source
Antioxidant Effects of SGLT2 Inhibitors on Cardiovascular–Kidney–Metabolic (CKM) Syndrome
AntioxidantsThe cardiovascular–kidney–metabolic (CKM) syndrome was recently conceptualized to provide a holistic framework for diagnosing and treating the full spectrum of key age-associated interrelated conditions: overweight/obesity, type 2 diabetes mellitus ...
Juan Guerrero-Mauvecin +8 more
doaj +1 more source