Results 71 to 80 of about 4,467,203 (335)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Mark Savickas’ theory as an inspiration for professional counselling aimed at adults enhanced with the application of Diagnostic and Simulation Games Method

Rocznik Andragogiczny, 2016
In case of adult learners, the process of professional counselling, diagnosing of professional predispositions or providing support for learners in their professional career construction frequently requires the application of different methods and ...
Przemysław Ziółkowski
doaj   +1 more source

Maladaptive repetition and career construction [PDF]

Journal of Vocational Behavior, 2012
Abstract The role of repeated maladaptive relationship patterns established early in life has been widely studied with the goal of understanding the various factors and processes that contribute to and occur during development and psychological adaptation.
openaire   +2 more sources

Individualized career counseling outcome assessment: A case study using the personal questionnaire [PDF]

, 2019
Career counseling evolved to practices that attribute a central importance to context variables and meaning-making processes. Accordingly, there is a call for the assessment of client’s subjectivity and cultural specificity, considering the interface ...
Cardoso, Paulo, Sales, Célia
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Understanding employee resourcing in construction organizations [PDF]

, 2008
In recent years the literature on employee resourcing has consistently advocated the importance of adopting a holistic, strategic approach to employee deployment decision making rather than adopting a reactive needs-based approach.
Anderson S. D., Andrew R. J. Dainty, Ani Birgit Raiden, Armstrong M., Armstrong M., Belbin R. M., Boxall P., Boyatzis R. E., Bramham J., Corbridge M., Druker J., Glaser B. G., Guest D., Hillebrandt P. M., Iles P., Langford D., Loosemore M., Marchington M., Margerison C., Miles M. B., Patton M. Q., Pfeffer J., Pilbeam S., Purcell J., Richard H. Neale, Taylor S., Torrington D., Ulrich D., Walker D. H. T., Watson T., Wood S., Yin R. K.   +31 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Occupation Profile: Librarians, October 5, 2017 [PDF]

, 2017
Construct, erect, install or repair structures and fixtures made of wood, such as concrete forms; building frameworks, including partitions, joists, studding, and rafters; and wood stairways, window and door frames, and hardwood floors.

core  

From Adaptive Readiness to Adaptation Results: Implementation of Student Career Construction Inventory and Testing the Career Construction Model of Adaptation

Journal of Career Assessment, 2020
This study evaluates the empirical applicability of the career construction model of adaptation (CCMA) by collecting evidence about the validity of the Student Career Construction Inventory (SCCI) from a sample of Turkish high school students and ...
Kemal Öztemel, E. Akyol
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source