Results 71 to 80 of about 4,308,682 (335)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Exploring the adolescents’ career development and career-related teacher support: the NEFELE career guidance model

open access: yesFrontiers in Psychology
IntroductionIn today’s dynamic landscape, navigating career paths in the midst of economic, societal, and technological changes has become increasingly challenging.
Anna Parola   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Occupation Profile: Carpenters, October 5, 2017 [PDF]

open access: yes, 2017
Construct, erect, install or repair structures and fixtures made of wood, such as concrete forms; building frameworks, including partitions, joists, studding, and rafters; and wood stairways, window and door frames, and hardwood floors.

core  

Maladaptive repetition and career construction [PDF]

open access: yesJournal of Vocational Behavior, 2012
Abstract The role of repeated maladaptive relationship patterns established early in life has been widely studied with the goal of understanding the various factors and processes that contribute to and occur during development and psychological adaptation.
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Career adaptability as an instructional scaffold for career education in South African schools

open access: yesAfrican Journal of Career Development
Background: South African learners need more career preparation, as it provides a sense of control in the current economic climate of high unemployment, as confirmed by the business sector.
Marlene Algra, Hermien Olivier
doaj   +1 more source

Mercato del lavoro e immigrazione in Spagna : disuguaglianze di genere e di etnia [PDF]

open access: yes, 2012
Background of INCASI Project H2020-MSCA-RISE-2015 GA 691004. WP1: CompilationThis article presents an analysis of the career paths of immigrant men and women in order to study the Spanish employment model.
Borràs Català, Vicent   +3 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

From Adaptive Readiness to Adaptation Results: Implementation of Student Career Construction Inventory and Testing the Career Construction Model of Adaptation

open access: yesJournal of Career Assessment, 2020
This study evaluates the empirical applicability of the career construction model of adaptation (CCMA) by collecting evidence about the validity of the Student Career Construction Inventory (SCCI) from a sample of Turkish high school students and ...
Kemal Öztemel, E. Akyol
semanticscholar   +1 more source

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