Results 71 to 80 of about 9,220 (223)

Carnosine supplementation and retina oxidative parameters in diet-induced obesity model [PDF]

, 2023
Rogil José de Almeida Torres, Fernando Moreto, Andréa Luchini, Rogerio Joao de Almeida Torres, Sofia Pimentel Longo, Ricardo A. Pinho, Seigo Nagashima, Lúcia de Noronha, Artur Júnio Togneri Ferron, Carol Vagula de Almeida Silva, Camila Renata Corrêa, Giancarlo Aldini, Ana Lúcia Anjos Ferreira   +12 more
openalex   +1 more source

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson, Lu Xia, Haiming Kerr, Marin Cabrera, Fabien Chu, Jaqueline Rose, Peter C. Wu, Atreya Dash, Sina A. Gharib, Jose M. Garcia   +9 more
wiley   +1 more source

Carnosine Ameliorates Stress-Induced Glucose Metabolism Disorder in Restrained Mice

Journal of Pharmacological Sciences, 2011
.: Carnosine is a natural dipeptide that has shown multiple benefits in the treatment of various diseases. This study investigated the ameliorative effects of carnosine on glucose metabolism in restraint-stressed mice.
Bun Tsoi, Rong-Rong He, Dong-Hui Yang, Yi-Fang Li, Xiao-Di Li, Wei-Xi Li, Keiichi Abe, Hiroshi Kurihara   +7 more
doaj   +1 more source

Inverting CEST or R1ρ$$ {R}_{1\uprho} $$ data to generate solute spectra without a priori assumptions

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 1239-1254, February 2026.
Abstract Purpose The goal of CEST imaging is to reveal the underlying tissue composition and exchange. However, quantitative CEST analyses typically require strong assumptions about this same composition and exchange. The goal of this paper is to introduce a new CEST analysis (also applicable to rotating frame relaxation rate R1ρ$$ {R}_{1\uprho ...
Daniel F. Gochberg
wiley   +1 more source

Evaluation of the sensitive skin syndrome and the effect of a dermo‐cosmetic treatment in Thai and Polish subjects

International Journal of Cosmetic Science, Volume 48, Issue 1, Page 70-82, February 2026.
Sensitive skin assessment in Thai and Polish subjects showed a dermo‐cosmetic product improved symptoms and quality of life in both groups, also highlighting ethnic differences in syndrome perception at baseline. Abstract Objective Sensitive skin syndrome (SSS) affects individuals from all ethnic groups.
Helena Polena, Sylwia Czaińska, Benoît Cadars, Ewa Chlebus, Monika Serafin, Waranya Boonchai, Pichanee Chaweekulrat, Silada Kanokrungsee, Marlène Chavagnac‐Bonneville, Christelle Graizeau, Michèle Sayag, Elodie Prestat‐Marquis   +11 more
wiley   +1 more source

Carnosine conformers

Biophysics, 2006
A semiempirical quantum chemical method PM3 was used to calculate the geometry and energy parameters of the most stable conformations of carnosine and its clusters with water and ...
openaire   +2 more sources

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Plasma extracellular vesicles from APOE3 Christchurch carriers display a protective phenotype in early stages of autosomal dominant Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez, David Aguillon, Juan Villar‐Vesga, Pablo Valderrama‐Carmona, Alejandro Guerrero, Anil Upreti, Said Arevalo‐Alquichire, Laura Correa, Karin Mendez‐Castellanos, Diana Castaño, Gloria P. Cardona‐Gomez, Geysson J. Fernandez, Leo A. Kim, Joseph F. Arboleda‐Velasquez, Rafael Posada‐Duque   +14 more
wiley   +1 more source

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang, Qianxue Lu, Panpan Jiao, Jun Jian, Qingyuan Zheng, Zhiyuan Chen, Xiuheng Liu, Shanshan Wan, Lei Wang   +8 more
wiley   +1 more source

Anti-aggregating effect of the naturally occurring dipeptide carnosine on aβ1-42 fibril formation.

PLoS ONE, 2013
Carnosine is an endogenous dipeptide abundant in the central nervous system, where by acting as intracellular pH buffering molecule, Zn/Cu ion chelator, antioxidant and anti-crosslinking agent, it exerts a well-recognized multi-protective homeostatic ...
Alessandra Aloisi, Amilcare Barca, Alessandro Romano, Sara Guerrieri, Carlo Storelli, Rosaria Rinaldi, Tiziano Verri   +6 more
doaj   +1 more source