Results 61 to 70 of about 6,763 (184)

A Systematic Review of Injectable Treatment Options for Horizontal Neck Rhytides

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Horizontal neck rhytides, commonly termed “tech neck lines,” represent an increasingly common aesthetic concern across age groups. Injectable treatments, including hyaluronic acid (HA) fillers and neuromodulators, are frequently employed; however, optimal modality selection and treatment protocols remain unclear.
Catherine F. Sollitto, Iya Agha, Maxim Narduzzi, Claire Wolinsky   +3 more
wiley   +1 more source

Carnosine suppresses neuronal cell death and inflammation induced by 6-hydroxydopamine in an in vitro model of Parkinson's disease.

PLoS ONE, 2020
Parkinson's disease is a progressive neurodegenerative disease for which prevention and effective treatments are lacking. The pathogenesis of Parkinson's disease is not clearly understood.
Maho Kubota, Nahoko Kobayashi, Toshifumi Sugizaki, Mikako Shimoda, Masahiro Kawahara, Ken-Ichiro Tanaka   +5 more
doaj   +1 more source

Anti-aggregating effect of the naturally occurring dipeptide carnosine on aβ1-42 fibril formation.

PLoS ONE, 2013
Carnosine is an endogenous dipeptide abundant in the central nervous system, where by acting as intracellular pH buffering molecule, Zn/Cu ion chelator, antioxidant and anti-crosslinking agent, it exerts a well-recognized multi-protective homeostatic ...
Alessandra Aloisi, Amilcare Barca, Alessandro Romano, Sara Guerrieri, Carlo Storelli, Rosaria Rinaldi, Tiziano Verri   +6 more
doaj   +1 more source

Safety of zinc l‐carnosine as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of zinc from this source in the context of Directive 2002/46/EC

EFSA Journal, Volume 24, Issue 6, June 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on zinc l‐carnosine as a novel food (NF) pursuant to Regulation (EU) 2015/2283 and as a source of zinc for use in food supplements. The NF is produced by chemical synthesis.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Monika Neuhäuser‐Berthold, Matthew Wright, Irene Nuin Garciarena, Ruth Roldán‐Torres, Areti Favata, Karen Ildico Hirsch‐Ernst   +25 more
wiley   +1 more source

Revealing the global mechanism related to carnosine synthesis in the pectoralis major of slow-growing Korat chickens using a proteomic approach [PDF]

Animal Bioscience
Objective This study aimed to find global mechanisms related to carnosine synthesis in slow-growing Korat chickens (KRC) using a proteomic approach. Methods M.
Panpradub Sinpru, Chanadda Suwanvichanee, Rujjira Bunnom, Satoshi Kubota, Jirawat Yongsawatdigul, Wittawat Molee, Kanjana Thumanu, Amonrat Molee   +7 more
doaj   +1 more source

Effects of carnosine supplementation on physical endurance: a placebo-controlled randomized clinical trial

Journal of the International Society of Sports Nutrition
Background Carnosine (β-alanine-L-histidine) is an endogenous dipeptide found in abundance in highly metabolic tissues such as skeletal muscle and the brain, where it is thought to play a role in intracellular buffering, and thereby, promote anaerobic ...
Timothy E. O'Toole, Christopher J. Wingard, Sonja K. Bariess, Catherine E. Crandell, Alok R. Amraotkar, Hong Gao, Aruni Bhatnagar   +6 more
doaj   +1 more source

Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling.

PLoS ONE, 2019
Glioblastoma is a high-grade glioma with poor prognosis even after surgery and standard therapy. Here, we asked whether carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, exert its anti-neoplastic effect on glioblastoma cells via PI3K/Akt/
Henry Oppermann, Helene Faust, Ulrike Yamanishi, Jürgen Meixensberger, Frank Gaunitz   +4 more
doaj   +1 more source

Effects of Carnosine on the Toxicity of Doxorubicin in Rabbits and Mice

Pteridines, 2003
The aim of this study was to establish the effect of naturally occurring antioxidant - carnosine - on the doxorubicin induced cardiotoxicity in a rabbit model.
Zieba Remigiusz, Czarnecka Elzbieta, Wągrowska-Danilewicz Małgorzata, Dzielska-Olczak Malgorzata, Graczyk Julita   +4 more
doaj   +1 more source

Carnosine ameliorates postoperative cognitive dysfunction of aged rats by limiting astrocytes pyroptosis

Neurotherapeutics
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in elderly patients, and neuroinflammation is a key hallmark. Recent studies suggest that the NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome ...
Jiahong Shen, Jiawen Xu, Yuxin Wen, Zili Tang, Jiaqi Li, Jianliang Sun   +5 more
doaj   +1 more source

The determination of carnosine [PDF]

Biochemical Journal, 1928
W M, Clifford, V H, Mottram
openaire   +2 more sources