Results 41 to 50 of about 10,570 (207)

Muscle carnosine in experimental autoimmune encephalomyelitis and multiple sclerosis [PDF]

, 2018
BACKGROUND: Muscle carnosine is related to contractile function (Ca++ handling) and buffering of exercise-induced acidosis. As these muscular functions are altered in Multiple Sclerosis (MS) it is relevant to understand muscle carnosine levels in MS ...
Eijnde, Bert O., Missinne, Maarten, Van Noten, Pieter, Inez Wens, Blancquaert, Laura, Derave, Wim, Charly Keytsman, Laura Blancquaert, Pieter Van Noten, Bert O. Eijnde, Missine, Maarten, Keytsman, Charly, Maarten Missine, Frank Vandenabeele, Wim Derave, Eijnde, Bert O, Vandenabeele, Frank, Wens, Inez   +17 more
core   +1 more source

Can the Skeletal Muscle Carnosine Response to Beta-Alanine Supplementation Be Optimized?

Frontiers in Nutrition, 2019
Carnosine is an abundant histidine-containing dipeptide in human skeletal muscle and formed by beta-alanine and L-histidine. It performs various physiological roles during exercise and has attracted strong interest in recent years with numerous ...
Pedro Perim, Felipe Miguel Marticorena, Felipe Ribeiro, Gabriel Barreto, Nathan Gobbi, Chad Kerksick, Eimear Dolan, Bryan Saunders, Bryan Saunders   +8 more
doaj   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Beta-alanine supplementation, muscle carnosine and exercise performance [PDF]

, 2015
Purpose of review : The use of dietary supplements in sports is widespread as athletes are continuously searching for strategies to increase performance at the highest level.
Derave, Wim, Everaert, Inge, Blancquaert, Laura   +2 more
core   +1 more source

Carnosine in health and disease

, 2019
Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle.
Rebecca Jones (17161051), Guilherme Giannini Artioli (9242588), Craig Sale (723461)   +2 more
core   +5 more sources

Investigation of Dose-Related Effects of Carnosine on Anxiety with Sympathetic Skin Response and T-maze

Acta Medica, 2014
Carnosine is a dipeptide formed of the amino acids β-alanine and histidine. Only a limited number of studies have examined the effects of carnosine on sympathetic nerve activation and anxiety.
Nazan Dolu, Hale Acer, Ali Yucel Kara
doaj   +1 more source

L-carnosine Attenuates Bleomycin-Induced Oxidative Stress via NFκB Pathway in the Pathogenesis of Pulmonary Fibrosis

Antioxidants, 2022
Idiopathic Pulmonary fibrosis (IPF), a chronic interstitial lung disease, has pulmonary manifestations clinically characterized by collagen deposition, epithelial cell injury, and a decline in lung function.
Jaehyun Park, Jimin Jang, Sang-Ryul Cha, Hyosin Baek, Jooyeon Lee, Seok-Ho Hong, Hyang-Ah Lee, Tae-Jin Lee, Se-Ran Yang   +8 more
doaj   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Effect of two beta-alanine dosing protocols on muscle carnosine synthesis and washout [PDF]

, 2011
Carnosine (β-alanyl-L-histidine) is found in high concentrations in skeletal muscle and chronic β-alanine (BA) supplementation can increase carnosine content. This placebo-controlled, double-blind study compared two different 8-week BA dosing regimens on
Stellingwerff, Trent, Anwander, Helen, Boesch, Chris, Buehler, Tania, Kreis, Roland, Decombaz, Jacques, Roland Kreis, Chris Boesch, Helen Anwander, Tania Buehler, Egger, Andrea, Andrea Egger, Trent Stellingwerff, Jacques Decombaz   +13 more
core   +2 more sources

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source