Results 31 to 40 of about 6,763 (184)
Antioxidants, 2021 Mitochondrial dysfunction in type 2 diabetes leads to oxidative stress, which drives disease progression and diabetes complications. L-carnosine, an endogenous dipeptide, improves metabolic control, wound healing and kidney function in animal models of ...
Cheng Schwank-Xu +8 more
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Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization
Frontiers in Physiology, 2019 High (millimolar) concentrations of the histidine containing dipeptide – carnosine (β-alanine-L-histidine) are present in the skeletal muscle. The dipeptide has been shown to buffer intracellular pH, chelate transition metals, and scavenge lipid ...
Adjoa A. Boakye +23 more
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Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance. [PDF]
PLoS ONE, 2012 Carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, has been characterized as a putative neurotransmitter and serves as a reservoir for brain histamine, which could act on histaminergic neurons system to relieve stress-induced damages ...
Yi-Fang Li +6 more
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Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model
Molecular Cancer, 2010 Background It was previously demonstrated that the dipeptide carnosine inhibits growth of cultured cells isolated from patients with malignant glioma.
Meixensberger Jürgen +8 more
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Carnosine attenuates vascular smooth muscle cells calcification through mTOR signaling pathway
Aging Medicine, 2020 Objective Vascular calcification is prevalent in the aging population, as we know that arterial calcification is associated with aging. Recent studies have demonstrated that carnosine, a naturally occurring dipeptide, performs the treatment of aging ...
Yi Huang +4 more
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CARNOSINE-CONTAINING LIPOSOMES: PREPARATION AND PROPERTIES
Тонкие химические технологии, 2016 Carnosine is a natural dipeptide antioxidant. It is proved that it protects human’s cells from oxidative stress. However, it has a short lifetime in a human organism due to the carnosinase activity.
N. A. Antonova +6 more
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Antioxidants, 2022 Idiopathic Pulmonary fibrosis (IPF), a chronic interstitial lung disease, has pulmonary manifestations clinically characterized by collagen deposition, epithelial cell injury, and a decline in lung function.
Jaehyun Park +8 more
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Iraqi Journal of Pharmaceutical SciencesDiabetes mellitus (DM) is a metabolic disorder specified by persistent hyperglycemia that occurs when β-cell insulin production became unable to control blood glucose with deterioration of response for insulin.
Haneen Subhee Shaheed, Shatha H Ali
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Acta Medica, 2014 Carnosine is a dipeptide formed of the amino acids β-alanine and histidine. Only a limited number of studies have examined the effects of carnosine on sympathetic nerve activation and anxiety.
Nazan Dolu, Hale Acer, Ali Yucel Kara
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Can the Skeletal Muscle Carnosine Response to Beta-Alanine Supplementation Be Optimized?
Frontiers in Nutrition, 2019 Carnosine is an abundant histidine-containing dipeptide in human skeletal muscle and formed by beta-alanine and L-histidine. It performs various physiological roles during exercise and has attracted strong interest in recent years with numerous ...
Pedro Perim +8 more
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