Results 31 to 40 of about 10,570 (207)

The effects of 5 days β-alanine supplementation on the velocity and the percentage o2max at the lactate threshold [PDF]

, 2010
Purpose: To assess the effect of 5 days β-alanine supplementation on the velocity and the percentage of O2max ¬¬ (%O2max) at the lactate threshold (Tlac) during treadmill running.
Johnson, Matthew
core   +2 more sources

Carnosine inhibits the proliferation of human gastric cancer SGC-7901 cells through both of the mitochondrial respiration and glycolysis pathways. [PDF]

PLoS ONE, 2014
Carnosine, a naturally occurring dipeptide, has been recently demonstrated to possess anti-tumor activity. However, its underlying mechanism is unclear.
Yao Shen, Jianbo Yang, Juan Li, Xiaojie Shi, Li Ouyang, Yueyang Tian, Jianxin Lu   +6 more
doaj   +1 more source

Improved Satellite Cell Proliferation Induced by L-Carnosine Benefits Muscle Growth of Pigs in Part through Activation of the Akt/mTOR/S6K Signaling Pathway

Agriculture, 2022
(1) Background: L-carnosine (β-alanyl-L-histidine), a natural dipeptide, exists at relatively high concentrations in skeletal muscles, and has been shown to protect cells from adverse conditions due to its antioxidant, anti-aging, anti-glycation, and ...
Yaojun Liu, Wenqiang Shen, Tao Liu, Rainer Mosenthin, Yinghui Bao, Peng Chen, Wenbo Hao, Lihong Zhao, Jianyun Zhang, Cheng Ji, Qiugang Ma   +10 more
doaj   +1 more source

Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization

Frontiers in Physiology, 2019
High (millimolar) concentrations of the histidine containing dipeptide – carnosine (β-alanine-L-histidine) are present in the skeletal muscle. The dipeptide has been shown to buffer intracellular pH, chelate transition metals, and scavenge lipid ...
Adjoa A. Boakye, Deqing Zhang, Deqing Zhang, Luping Guo, Luping Guo, Yuting Zheng, Yuting Zheng, David Hoetker, David Hoetker, Jingjing Zhao, Jingjing Zhao, Dheeraj Kumar Posa, Dheeraj Kumar Posa, Chin K. Ng, Huaiyu Zheng, Amit Kumar, Vijay Kumar, Michael F. Wempe, Aruni Bhatnagar, Aruni Bhatnagar, Daniel J. Conklin, Daniel J. Conklin, Shahid P. Baba, Shahid P. Baba   +23 more
doaj   +1 more source

Carnosine attenuates vascular smooth muscle cells calcification through mTOR signaling pathway

Aging Medicine, 2020
Objective Vascular calcification is prevalent in the aging population, as we know that arterial calcification is associated with aging. Recent studies have demonstrated that carnosine, a naturally occurring dipeptide, performs the treatment of aging ...
Yi Huang, Jinli Wang, Mandi Luo, Dan Yan, Cuntai Zhang   +4 more
doaj   +1 more source

Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance. [PDF]

PLoS ONE, 2012
Carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, has been characterized as a putative neurotransmitter and serves as a reservoir for brain histamine, which could act on histaminergic neurons system to relieve stress-induced damages ...
Yi-Fang Li, Rong-Rong He, Bun Tsoi, Xiao-Di Li, Wei-Xi Li, Keiichi Abe, Hiroshi Kurihara   +6 more
doaj   +1 more source

L-Carnosine Stimulation of Coenzyme Q10 Biosynthesis Promotes Improved Mitochondrial Function and Decreases Hepatic Steatosis in Diabetic Conditions

Antioxidants, 2021
Mitochondrial dysfunction in type 2 diabetes leads to oxidative stress, which drives disease progression and diabetes complications. L-carnosine, an endogenous dipeptide, improves metabolic control, wound healing and kidney function in animal models of ...
Cheng Schwank-Xu, Elisabete Forsberg, Magnus Bentinger, Allan Zhao, Ishrath Ansurudeen, Gustav Dallner, Sergiu-Bogdan Catrina, Kerstin Brismar, Michael Tekle   +8 more
doaj   +1 more source

Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model

Molecular Cancer, 2010
Background It was previously demonstrated that the dipeptide carnosine inhibits growth of cultured cells isolated from patients with malignant glioma.
Meixensberger Jürgen, Gebhardt Rolf, Hengstler Jan, Hermes Matthias, Geiger Kathrin D, Fuchs Beate, Zemitzsch Nadine, Renner Christof, Gaunitz Frank   +8 more
doaj   +1 more source

Carnosine-Modified Fullerene as a Highly Enhanced ROS Scavenger for Mitigating Acute Oxidative Stress

, 2020
Fullerenes are known as highly efficient scavengers for reactive oxygen species (ROSs). In this study, a carnosine-modified fullerene derivative (C60–Car) was synthesized via a one-step nucleophilic addition reaction.
Yen Wei (1396648), Haijun Ma (809489), Jiajia Zhao (537913), Danning Hu, Yue Zhou (71752), Haibing Meng, Yue Zhou, Haijun Ma, Xiaoyan Zhang (50085), Jie Li, Xiaoyan Zhang, Jinying Yuan (2285431), Chunru Wang, Danning Hu (3222912), Jinying Yuan, Chunru Wang (1472767), Haibing Meng (4867693), Jiajia Zhao, Jie Li (15030), Yen Wei   +19 more
core   +1 more source

Genetic Polymorphisms of Carnosine Synthase -1(ATPGD1) and Serum Carnosine Levels in Relation to Cardiovascular Diseases in Iraqi Type 2 Diabetics

Iraqi Journal of Pharmaceutical Sciences
Diabetes mellitus (DM) is a metabolic disorder specified by persistent hyperglycemia that occurs when β-cell insulin production became unable to control blood glucose with deterioration of response for insulin.
Haneen Subhee Shaheed, Shatha H Ali
doaj   +1 more source