Results 11 to 20 of about 6,763 (184)

Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation

Antioxidants, 2021
Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is present in all vertebrates.
Ivana Jukic, Nikolina Kolobaric, Ana Stupin   +2 more
exaly   +3 more sources

Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle

Redox Biology, 2018
Previous studies have demonstrated that exercise results in reactive aldehyde production and that β-alanine supplementation increases carnosine content in skeletal muscle.
Luana Farias De Oliveira, Paolo Di Mascio, Bruno Gualano   +2 more
exaly   +3 more sources

Looking Under the Hood of Elite Rowers: Skeletal Muscle Determinants of Rowing Performance. [PDF]

Scand J Med Sci Sports
ABSTRACT We aimed to identify the physiological and muscle characteristics associated with mean power output in the final stage of a rowing incremental test in elite rowers. Twenty‐two national level rowers (n = 9 female) completed the following assessments (i) a 7‐stage incremental rowing ergometer test to determine V̇O2peak, maximal muscle ...
Bellinger P, Dick T, Roberts L, Minahan C, Takahashi K, Charles JP, Hannah K, Wackwitz T, Lievens E, Casteele FV, Kennedy B, Duhig S.   +11 more
europepmc   +2 more sources

Thermodynamic and voltammetric study on carnosine and ferrocenyl-carnosine

Dalton Transactions, 2023
An electroactive carnosine derivative (ferrocenyl-carnosine, FcCAR (L)) was synthesized and its complexing and sensing properties were evaluated; it was found to be promising for the electrochemical detection of Hg2+and Pb2+in an aqueous environment.
Chiara Abate, Anna Piperno, Alex Fragoso, Ottavia Giuffrè, Antonino Mazzaglia, Angela Scala, Claudia Foti   +6 more
openaire   +3 more sources

CARNOSINE-LOADED ORAL NIOSOMES AMELIORATE HIGH-FRUCTOSE-INDUCED METABOLIC SYNDROME IN RATS VIA MODULATION OF SIRT1, A METABOLIC MASTER SWITCH

Slovenian Veterinary Research, 2023
Metabolic syndrome is a crucial health challenge, and the available therapeutic agents are still not effective. Carnosine, a cytoplasmic dipeptide, is a potent anti-glycation, anti-oxidant, anti-inflammatory and chelating agent.
Amany I Ahmed, Nada Y. Nasr, Mahmoud A. Said, Reham H. Alattar, Khalifa El-Dawy   +4 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

Journal of Neuroinflammation, 2021
Background Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of the pathological hallmarks of MS is extensive free radical production. However, the subsequent generation, potential
Jan Spaas, Wouter M. A. Franssen, Charly Keytsman, Laura Blancquaert, Tim Vanmierlo, Jeroen Bogie, Bieke Broux, Niels Hellings, Jack van Horssen, Dheeraj Kumar Posa, David Hoetker, Shahid P. Baba, Wim Derave, Bert O. Eijnde   +13 more
doaj   +1 more source

Carnosine Potentiates Doxorubicin-Induced Cytotoxicity in Resistant NCI/ADR-RES Cells by Inhibiting P-Glycoprotein—In Silico and In Vitro Evidence

Molecules, 2022
The activity of the P-glycoprotein (P-gp) transporter encoded by the ABCB1 gene confers resistance to anticancer drugs and contributes to cancer-related mortality and morbidity.
Mohamed A. Morsy, Mahmoud Kandeel, Ahmed R. N. Ibrahim, Seham A. Abdel-Gaber, Shery Jacob, Katharigatta N. Venugopala, Pottathil Shinu, Mahmoud El-Daly   +7 more
doaj   +1 more source

Regulation of mitochondrial function and energy metabolism: A primary mechanism of cytoprotection provided by carnosine [PDF]

Trends in Pharmaceutical Sciences, 2018
Carnosine is an abundantly found dipeptide present in different tissues. Several pharmacological properties have been attributed to carnosine. On the other hand, the precise mechanism of cytoprotection provided by carnosine remains obscure.
Reza Heidari, Vahid Ghanbarinejad, Mohammad Mehdi Ommati, Akram Jamshidzadeh, Hossein Niknahad   +4 more
doaj   +3 more sources

Carnosine and bone (Review)

Molecular Medicine Reports, 2022
Carnosine is a vital endogenous dipeptide that has anti‑inflammatory, antiaging, anti‑crosslinking, antitumor and immune regulatory effects. Numerous cell and animal model studies have proved that carnosine and its compounds promote the proliferation and differentiation of osteoblasts, inhibit osteoclasts and protect chondrocytes.
Yang, Hao, Hou, Xiaoli, Xing, Lei, Tian, Faming   +3 more
openaire   +2 more sources