Results 11 to 20 of about 15,119 (225)

Effect of pork carnosine level on lipid and protein oxidation markers during in vitro co-digestion in a Mediterranean meal model. [PDF]

J Sci Food Agric
Abstract BACKGROUND This study assessed the effects of dietary carnosine during the in vitro digestion of a healthy meal model based on the Mediterranean diet, comprising lean pork enriched with two levels of carnosine, whole grain bread, tomato, onion, and olive oil.
Li YY, Yaylayan V, Palin MF, Ngapo TM, Cliche S, Gagnon F, Gariépy C.   +6 more
europepmc   +2 more sources

Reduced Muscular Carnosine in Proximal Myotonic Myopathy-A Pilot ¹H-MRS Study. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Gussew A, Kargaran M, Rothe M, Deistung A, Stoevesandt D, Wohlgemuth WA, Strube D, Kendzierski T, Kölsch AK, Heuschen MGA, Otto M, Mensch A.   +11 more
europepmc   +2 more sources

Effect of histidine and carnosine on haemoglobin recovery in anaemia induced-kidney damage and iron-loading mouse models [PDF]

Amino Acids
Histidine and carnosine can form complexes with divalent metal ions such as Fe2+, potentially providing stability to intracellular labile iron.
Mayra Vera-Aviles, Jorge Moreno-Fernandez, Tugba Kose, Robert Hider, Gladys O. Latunde-Dada   +4 more
doaj   +2 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Effects of beta-alanine supplementation on brain homocarnosine/carnosine signal and cognitive function: an exploratory study [PDF]

, 2015
Objectives: Two independent studies were conducted to examine the effects of 28 d of beta-alanine supplementation at 6.4 g d-1 on brain homocarnosine/carnosine signal in omnivores and vegetarians (Study 1) and on cognitive function before and after ...
A Boldyrev, A Bruun, AA Boldyrev, AA Boldyrev, AA Boldyrev, AC Parrott, AM Asatoor, AM Hoffmann, AR Hipkiss, B Herculano, Bruno Gualano, C Sale, CA Hill, Catherine A. Brissette, Craig Sale, D Dobrota, Daniel Martin, DG Altman, DL Rothman, DL Rothman, E Hogervorst, G Aldini, Guilherme G. Artioli, H Abe, Hamilton Roschel, I Everaert, J Komura, Jacques Robertson, JE Preston, JN E-AS Baraniuk, JR Hoffman, JR Stroop, JW Harding, K Bauer, KN Chengappa, M Dunnett, M Gross, M Yazigi Solis, MA Kamal, Maria C. Otaduy, Marina Yazigi Solis, MS Horning, MS Ozdemir, NS Teuscher, OA Petroff, P Vermathen, R Hobson, R Leech, R Weinsier, RC Harris, Roger C. Harris, Ruth M Hobson, S Sternberg, S Stvolinsky, SB Cooper, Simon Cooper, SJ Kish, T McMorris, T Murakami, T Stellingwerff, TL Perry, TN Fedorova, Vitor S. Painelli   +62 more
core   +8 more sources

Carnosine and bone (Review)

Molecular Medicine Reports, 2022
Carnosine is a vital endogenous dipeptide that has anti‑inflammatory, antiaging, anti‑crosslinking, antitumor and immune regulatory effects. Numerous cell and animal model studies have proved that carnosine and its compounds promote the proliferation and differentiation of osteoblasts, inhibit osteoclasts and protect chondrocytes.
Yang, Hao, Hou, Xiaoli, Xing, Lei, Tian, Faming   +3 more
openaire   +2 more sources

Evaluation of Antidiabetic and Antioxidant Activities of L-carnosine using Enzyme Inhibition and Free Radical Scavenging Assays: An In-vitro Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Diabetes is a chronic disease that causes dysfunction of various organs and tissues resulting in end organ damage and premature mortality. Oxidative stress is a main factor of diabetic complications.
D Malathy, D Anusha, K Karthika, K Punnagai   +3 more
doaj   +1 more source

Characterisation of intracellular molecular mechanisms modulated by carnosine in porcine myoblasts under basal and oxidative stress conditions.

PLoS ONE, 2020
Carnosine is a naturally occurring histidine-containing dipeptide present at high concentration in mammalian skeletal muscles. Carnosine was shown to affect muscle contraction, prevent the accumulation of oxidative metabolism by-products and act as an ...
Marie-France Palin, Jérôme Lapointe, Claude Gariépy, Danièle Beaudry, Claudia Kalbe   +4 more
doaj   +2 more sources

Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]

, 2010
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey, Beeckman, Sam, Derave, Wim, Everaert, Inge   +3 more
core   +2 more sources

The ergogenic effect of beta-alanine combined with sodium bicarbonate on high-intensity swimming performance [PDF]

, 2013
We investigated the effect of beta-alanine (BA) alone (study A) and in combination with sodium bicarbonate (SB) (study B) on 100- and 200-m swimming performance. In study A, 16 swimmers were assigned to receive either BA (3.2 g·day−1 for 1 week and 6.4 g·
Antonio Herbert Lancha, Artioli G.G., Artioli G.G., Batterham A.M., Bonifazi M., Bruno Gualano, Craig Sale, Fabiana Braga Benatti, Fabiato A., Flávia de Jesus, Guilherme Giannini Artioli, Hamilton Roschel, Marina Yázigi Solis, Pruscino C.L., Roger Charles Harris, Sutton J.R., Vitor de Salles Painelli   +16 more
core   +1 more source