Results 11 to 20 of about 10,570 (207)
Carnosine in health and disease [PDF]
European Journal of Sport Science, 2018 AbstractCarnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of ...
Artioli, GG, Sale, C, Jones, RL
openaire +6 more sources
An update on carnosine and anserine research [PDF]
Amino Acids, 2019 Carnosine belongs to a family of histidyl dipeptides, consisting of l-histidine and beta-alanine. It is more prevalent in the mammalian and human tissues, whereas its analogues such as anserine, which is methylated at the Nπ of imidazole, is present in birds and fish and balenine, methylated at the Nτ of histidine, is largely present in marine mammals ...
Wim Derave +2 more
openaire +4 more sources
Amino AcidsCarnosine’s protective effect in rodent models of glycoxidative stress have provided a rational for translation of these findings in therapeutic concepts in patient with diabetic kidney disease.
Shiqi Zhang +8 more
doaj +2 more sources
Carnosine and Carnosine-Related Antioxidants: A Review
Current Medicinal Chemistry, 2005 First isolated and characterized in 1900 by Gulewitsch, carnosine ( β-alanyl-L-hystidine) is a dipeptide commonly present in mammalian tissue, and in particular in skeletal muscle cells; it is responsible for a variety of activities related to the detoxification of the body from free radical species and the by-products of membrane lipids ...
Andrea Guiotto +3 more
openaire +5 more sources
Journal of the International Society of Sports Nutrition, 2012 Background Carnosine is a dipeptide that improves exercise performance. The carnosine synthesis mechanism through carnosine and ß-alanine ingestion remains unclear.
Miyaji Takayuki +4 more
doaj +2 more sources
Phytosome-hyaluronic acid systems for ocular delivery of L-carnosine [PDF]
, 2016 This study reports on L-carnosine phytosomes as an alternative for the prodrug N-acetyl-L-carnosine as a novel delivery system to the lens. L-carnosine was loaded into lipid-based phytosomes and hyaluronic acid (HA)-dispersed phytosomes.
Michael R. Longman (16674669) +3 more
core +8 more sources
Physiology and Pathophysiology of Carnosine
Physiological Reviews, 2013 Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal muscle, but also in other excitable tissues. Most animals, except humans, also possess a methylated variant of carnosine, either anserine or ophidine/balenine, collectively called the ...
A. A. Boldyrev, G. Aldini, W. Derave
openaire +3 more sources
CARNOSINE-CONTAINING LIPOSOMES: PREPARATION AND PROPERTIES [PDF]
Тонкие химические технологии, 2016 Carnosine is a natural dipeptide antioxidant. It is proved that it protects human’s cells from oxidative stress. However, it has a short lifetime in a human organism due to the carnosinase activity.
N. A. Antonova +6 more
doaj +2 more sources
Thermodynamic and voltammetric study on carnosine and ferrocenyl-carnosine
Dalton Transactions, 2023 An electroactive carnosine derivative (ferrocenyl-carnosine, FcCAR (L)) was synthesized and its complexing and sensing properties were evaluated; it was found to be promising for the electrochemical detection of Hg 2+ and Pb 2+ in an aqueous environment.
Chiara Abate +6 more
openaire +3 more sources
Molecules, 2022 The activity of the P-glycoprotein (P-gp) transporter encoded by the ABCB1 gene confers resistance to anticancer drugs and contributes to cancer-related mortality and morbidity.
Mohamed A. Morsy +7 more
doaj +1 more source