Results 51 to 60 of about 10,570 (207)

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Effects of carnosine supplementation on glucose metabolism : pilot clinical trial [PDF]

, 2016
OBJECTIVE: Carnosine is a naturally present dipeptide in humans and an over-the counter food additive. Evidence from animal studies supports the role for carnosine in the prevention and treatment of diabetes and cardiovascular disease, yet there is ...
G. Aldini, H. J. Teede, Teede, HJ, W. Derave, Silvia Barbaresi, Ukropcova, Barbara, de Courten, Maximilian, Barbaresi, Silvia, D. Garzon, Aldini, Giancarlo, Kurdiova, Timea, J. Ukropec, Krumpolec, Patrik, Derave, Wim, Aldini, G, Jakubova, Michaela, Krssak, Martin, de Courten, B, L. Valkovic, T. Kurdiova, Davide Garzon, Maximilian PJ de Courten, Teede, Helena J, Helena J. Teede, Kukurova, Ivica Just, Jakubova, M, Krssak, M, Kurdiova, T, B. Ukropcova, Garzon, Davide, I. J. Kukurova, S. Barbaresi, Timea Kurdiova, Wim Derave, Barbora de Courten, et al., Ladislav Valkovic, de Courten, Barbora, Krumpolec, P, Valkovic, Ladislav, Ukropec, J, S. Vallova, Giancarlo Aldini, Ukropcova, B, Silvia Vallova, Ukropec, Jozef, Barbaresi, S, Barbara Ukropcova, B. de Courten, Kukurova, IJ, M. Krssak, de Courten, MP, Garzon, D, P. Krumpolec, Michaela Jakubova, Vallova, S, Martin Krssak, Patrik Krumpolec, Valkovic, L, M. Jakubova, de Courten, Maximilian PJ, M. P. de Courten, Vallova, Silvia, Derave, W, Jozef Ukropec, Ivica Just Kukurova   +65 more
core   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

The Therapeutic Potential of Novel Carnosine Formulations: Perspectives for Drug Development

Pharmaceuticals, 2023
Carnosine (beta-alanyl-L-histidine) is an endogenous dipeptide synthesized via the activity of the ATP-dependent enzyme carnosine synthetase 1 and can be found at a very high concentration in tissues with a high metabolic rate, including muscles (up to ...
Angela Bonaccorso, Anna Privitera, Margherita Grasso, Sonya Salamone, Claudia Carbone, Rosario Pignatello, Teresa Musumeci, Filippo Caraci, Giuseppe Caruso   +8 more
doaj   +1 more source

Integrated Multi‐Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep

Integrative Zoology, EarlyView.
SNaPshot‐validated GWAS results demonstrated significant correlations between candidate single nucleotide polymorphisms (SNPs) and body size traits in Tibetan sheep. Concurrently, hematoxylin and eosin staining, alongside muscle fiber analysis, confirmed pronounced morphological differences in muscle tissue between sheep of varying conformation.
Dehui Liu, Xue Li, Fei Tian, Xuexia Li, Wenxia Li, Buying Han, Ming Jiang, Yanlan Liu, Xiliu Hu, Xue Xiang, Wulong Ma, Guangcai Bao, Rong Li, Guoxiang Bao, Sijia Liu, Kai Zhao, Dehong Tian   +16 more
wiley   +1 more source

Dietary carnosine intake improves outcomes in Experimental Autoimmune Encephalomyelitis

, 2019
Background: Carnosine (C9H14N4O3) is a naturally occurring dipeptide synthetized from histidine and β-alanine that is mainly found in excitable tissues such as skeletal muscle and the central nervous system (CNS).
Vanmierlo, T, Eijnde, BO, Franssen, W, Bogie, J, Derave, W, Spaas, J   +5 more
core   +1 more source

Optimizing human in vivo dosing and delivery of β-alanine supplements for muscle carnosine synthesis [PDF]

, 2012
Interest into the effects of carnosine on cellular metabolism is rapidly expanding. The first study to demonstrate in humans that chronic β-alanine (BA) supplementation (~3-6 g BA/day for ~4 weeks) can result in significantly augmented muscle carnosine ...
Stellingwerff, Trent, Boesch, Chris, Harris, Roger C, Decombaz, Jacques   +3 more
core   +2 more sources

Carnosine Activates Cellular Stress Response in Podocytes and Reduces Glycative and Lipoperoxidative Stress

Biomedicines, 2020
Carnosine improves diabetic complications, including diabetic nephropathy, in in vivo models. To further understand the underlying mechanism of nephroprotection, we studied the effect of carnosine under glucose-induced stress on cellular stress response ...
Maria Scuto, Angela Trovato Salinaro, Sergio Modafferi, Alessandra Polimeni, Tilman Pfeffer, Tim Weigand, Vittorio Calabrese, Claus Peter Schmitt, Verena Peters   +8 more
doaj   +1 more source

Carnosine Content and Its Association with Carnosine-Related Gene Expression in Breast Meat of Thai Native and Black-Bone Chicken

Animals, 2021
This study aimed to investigate the carnosine content and ATP-grasp domain-containing protein 1 (CARNS1) gene expression and their relationship with breast meat of Black Chinese (BC), KU-Phuparn (KP), Pradu Hang Dam (PD), and Black Chinese × Pradu Hang ...
Panuwat Khumpeerawat, Monchai Duangjinda, Yupin Phasuk   +2 more
doaj   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source