Results 51 to 60 of about 15,119 (225)
Journal of the International Society of Sports Nutrition, 2012 Background Carnosine is a dipeptide that improves exercise performance. The carnosine synthesis mechanism through carnosine and ß-alanine ingestion remains unclear.
Miyaji Takayuki +4 more
doaj +1 more source
Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]
, 2018 BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach +25 more
core +4 more sources
Zinc, Carnosine, and Neurodegenerative Diseases [PDF]
Nutrients, 2018 Zinc (Zn) is abundantly present in the brain, and accumulates in the synaptic vesicles. Synaptic Zn is released with neuronal excitation, and plays essential roles in learning and memory. Increasing evidence suggests that the disruption of Zn homeostasis is involved in various neurodegenerative diseases including Alzheimer’s disease, a vascular type of
Masahiro Kawahara +2 more
openaire +2 more sources
Equine Veterinary Journal, EarlyView.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source
The Therapeutic Potential of Novel Carnosine Formulations: Perspectives for Drug Development
Pharmaceuticals, 2023 Carnosine (beta-alanyl-L-histidine) is an endogenous dipeptide synthesized via the activity of the ATP-dependent enzyme carnosine synthetase 1 and can be found at a very high concentration in tissues with a high metabolic rate, including muscles (up to ...
Angela Bonaccorso +8 more
doaj +1 more source
Exercise training and beta-alanine-induced muscle carnosine loading [PDF]
, 2015 PURPOSE: Beta-alanine (BA) supplementation has been shown to augment muscle carnosine concentration, thereby promoting high-intensity (HI) exercise performance.
Achten, Eric +4 more
core +3 more sources
Determinants of muscle carnosine content [PDF]
Amino Acids, 2012 The main determinant of muscle carnosine (M-Carn) content is undoubtedly species, with, for example, aerobically trained female vegetarian athletes [with circa 13 mmol/kg dry muscle (dm)] having just 1/10th of that found in trained thoroughbred horses.
Harris, R. C. +5 more
openaire +2 more sources
The protective effect of exercise on diabetic nephropathy : the role of histidine-containing dipeptides [PDF]
, 2017 C
Baba, Shahid P +7 more
core +1 more source
Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage [PDF]
, 2014 Background and Purpose—Despite the rapidly increasing global burden of ischemic stroke, no therapeutic options for neuroprotection against stroke currently exist.
Akram, M. +8 more
core +2 more sources
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source